COVEXIN^® 8 VACCINE

Schering-Plough

CLOSTRIDIUM CHAUVOEI-SEPTICUM-HAEMOLYTICUM-NOVYI-TETANI-PERFRINGENS TYPES C & D BACTERIN-TOXOID

INDICATIONS

For the vaccination of healthy cattle and sheep against diseases caused by Clostridium chauvoei, Cl. septicum, Cl. novyi Type B, Cl. haemolyticum (known elsewhere as Cl. novyi Type D), Cl. tetani and Cl. perfringens Types C and D.

Although Clostridium perfringens Type B is not considered a significant problem in the U.S.A., immunity may be provided against the beta and epsilon toxins elaborated by Cl. perfringens Type B. The immunity is derived from the combination of Type C (beta) and Type D (epsilon) fractions.

ADMINISTRATION AND DOSAGE

Shake well. Using aseptic technique

Cattle dosage: Inject 5 mL subcutaneously or intramuscularly, repeated in 6 weeks. Revaccinate annually with 5 mL prior to periods of extreme risk or parturition. For animals subject to reexposure to Cl. novyi Type B and Cl. haemolyticum repeat the dose every 5 to 6 months. For Cl. perfringens Types B, C and D, revaccinate two weeks prior to parturition, introduction to lush pastures or finishing programs. Calves vaccinated under 3 months of age should be revaccinated at weaning or 4 to 6 months of age.

Sheep dosage: Inject 5 mL subcutaneously followed by a 2 mL dose in 6 weeks. Revaccinate annually with 2 mL prior to periods of extreme risk or parturition. For Cl. novyi and Cl. haemolyticum, revaccinate every 5 to 6 months. Vaccination should be scheduled so that pregnant ewes receive their second vaccination or annual booster 2 to 6 weeks before lambing commences in the flock. Lambs should be given their primary course beginning at 10 to 12 weeks of age.

PRECAUTION

This product has been tested under laboratory conditions and shown to meet all Federal standards for safety and efficacy. This level of performance may be affected by conditions of use such as stress, weather, nutrition, disease, parasitism, other treatments, individual idiosyncrasies or impaired immunological competency. These factors should be considered by the user when evaluating product performance or freedom from reactions.

Local reactions may be observed following subcutaneous administration to cattle.

CAUTION

Store at 35°-45°F (2°-7°C). Protect from freezing. Use entire contents when first opened. Do not vaccinate within 21 days before slaughter. Anaphylactic reactions may occur following use.

Antidote: Epinephrine.

Manufactured by

SCHERING-PLOUGH ANIMAL HEALTH LIMITED

UPPER HUTT, NEW ZEALAND

Distributed by

SCHERING-PLOUGH ANIMAL HEALTH CORP.

OMAHA, NE 68103 U.S.A.

U.S. Veterinary Permit No. 311

FOR VETERINARY USE ONLY

Copyright © 1997 Schering-Plough Animal Health Corp.

Omaha, NE 68103 U.S.A.

Covexin 8 is a registered trademark of Schering-Plough Animal Health Corporation.

Disclaimer: Every effort has been made to ensure the accuracy of the information published. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the product label or package insert. NAC No.: 10470331