Schering-Plough

Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia PsittaciVaccine

MODIFIED LIVE VIRUS AND CHLAMYDIAAND KILLED VIRUS

For veterinary use in cats only

PRODUCT DESCRIPTION:

Eclipse* 4 + FeLV vaccine is a combination vaccine that unites the benefits of Eclipse* 4 and Fevaxyn* FeLV in one vaccination.

Eclipse 4 vaccine is a modified live virus and chlamydia vaccine for the vaccination of healthy cats as an aid in the prevention of disease caused by feline rhinotracheitis, calici, and panleukopeniaviruses and Chlamydia psittaci.

Fevaxyn FeLV vaccine is recommended for the vaccination of healthy cats as an aid in the prevention of lymphoid tumors caused by, and diseases associated with, feline leukemia virus (FeLV) infection. Vaccination with this product prevents persistent viremia in cats exposed to virulent feline leukemia virus.

Fevaxyn FeLV contains a tissue culture derived feline leukemia virus, Subgroups A and B. The virus has been chemically inactivated and combined with a proprietary adjuvant designed to enhance the immune response.

DOSAGE AND ADMINISTRATION:

Prior to use, warm the Fevaxyn FeLV to room temperature and shake well.

Transfer contents of the Fevaxyn FeLV vial to the Eclipse 4 vial aseptically. Mix gently until dissolved. Use entire contents immediately after rehydration.

Two doses are required for primary immunization.

Initial vaccination: Inject 1 dose (1 mL) subcutaneously or intramuscularly at 9 weeks of age or older.

Second vaccination: Inject 1 dose (1 mL) subcutaneously or intramuscularly 3 to 4 weeks following the initial vaccination.

Annual revaccination with one dose is recommended.

PRECAUTIONS:

Store at 2°-7°C.

Do not freeze.

Do not mix with other vaccines.

Use new, non-chemically sterilized needles and syringes.

Burn vaccine container and all unused contents.

WARNINGS:

Contains gentamicin and amphotericin B as preservatives.

Some reports suggest that in cats, the administration of certain veterinary biologicals may induce the development of injection-site fibrosarcomas.

Do not vaccinate pregnant cats.

The use of a biological product may produce anaphylaxis and/or other inflammatory immune-mediated hypersensitivity reactions. Antidote: Epinephrine, corticosteroids, and antihistamines may all be indicated depending on the nature and severity of the reaction.

It is important to realize that certain conditions and events may cause some cats to be unable to develop or maintain an adequate immune response following FeLV vaccination. Prior exposure to the disease, or disease latency, are conditions in which vaccination will not alter the course of the disease. Therefore, diagnostic testing of all cats for FeLV antigen prior to vaccination is recommended. Also, vaccination with this product will not offer cross-protection against feline immunodeficiency (FIV), another feline retrovirus. It is important to advise the cat owner of these situations prior to vaccination.