PROPALIN is recommended for the long-term management of urinary incontinence associated with urethral sphincter incompetence in spayed dogs. Urinary incontinence is particularly common in bitches which have undergone an ovariectomy. They wet their bedding and urinate in various places around the house. They are unaware of this and consequently need to be treated, not punished! Urinary retention is achieved by means of the urethral sphincter, a muscular mechanism governed by the nervous system.

 

The sphincter is usually closed until the animal decides to urinate. However, when the sphincter is lax, incontinence occurs. Vétoquinol is a forerunner in the treatment of this problem, with Propalin contains phenylpropanolamine. Propalin for dog is a sympathomimetic; it increases the tonus of the muscles in the urethral sphincter.

Propalin is quickly absorbed, with a concentration peak of 1 to 3 hours after administration. Propalin is effective immediately, at the following dose: 0.75 ml for a bitch weighing 25 kg. The graduated syringe ensures that the correct dose is administered.

 

A non-hormonal therapeutic agent, Propalin® is remarkably well tolerated. Propalin is available in 30 ml dropper vials and 100 ml vials with graduated syringe, so that exactly the right dose is given. Very easy to use and well tolerated, Propalin is the right remedy to bring relief to dogs and owners alike! With Propalin, everyone in the house stays nice and dry!

 

DOSAGE AND ADMINISTRATION Administer orally with food, 3 mg/kg B.W. per day divided in 2 or 3 equal doses: TABLETS Divided in 2 doses - Administer 1.5 mg/kg B.W. (1 PROPALIN™ 50 mg tablet/34 kg B.W. 1/2 tablet/17 kg B.W.) two times daily. For smaller dogs, administer 1.5 mg/kg B.W. (1 PROPALIN™ 25 mg tablet/17 kg B.W. 1/2 tablet/8.3 kg B.W.) two times daily. For larger dogs, administer 1.5 mg/kg B.W. (1 PROPALIN™ 75 mg tablet/50 kg B.W. 1/2 tablet/25 kg B.W.) two times daily. Divided in 3 doses - Administer 1.0 mg/kg B.W. (1 PROPALIN™ 50 mg tablet/50 kg B.W. 1/2 tablet/25kg B.W.) three times daily. For smaller dogs, administer 1.0 mg/kg B.W. (1 PROPALIN™ 25 mg tablet/25 kg B.W. 1/2 tablet/12.5kg B.W.) three times daily. For larger dogs, administer 1.0 mg/kg B.W. (1 PROPALIN™ 75 mg tablet/75 kg B.W. 1/2 tablet/75 kg B.W.) three times daily. SYRUP Divided in 2 doses - Administer 1.5 mg/kg B.W. (3 drops of PROPALIN™ Syrup/4 kg B.W.) two times daily. For large dogs, the dosage of 1.5 mg/kg B.W. two times daily may be measured with an oral syringe at a rate of 0.75 ml per 25 kg B.W. twice daily. Divided in 3 doses - Administer 1.0 mg/kg B.W. (2 drops of PROPALIN™ Syrup/4 kg B.W.) three times daily. For large dogs, the dosage of 1.0 mg/kg B.W. three times daily may be measured with an oral syringe at a rate of 0.5 ml per 25 kg B.W. twice daily. If clinical response is poor, the initial diagnosis should be reconsidered. For this drug to be effective, it must be administrated as directed. Missed doses will negate its effect.

 

CONTRAINDICATION(S)Do not use in animals with pre-existing medical conditions (e.g. cardiovascular disease, renal insufficiency). Do not use in animals taking cardiovascular medications or any other sympathomimetic agents.