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  Lysodren (mitotane)
  Lysodren (mitotane)
Lysodren (mitotane)
 

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Lysodren (mitotane) is used in veterinary medicine to treat dogs with Cushing's disease. Indications: Mitotane is used in the treatment of Cushing’s disease in dogs.

 


Item# Item Name Allivet Price Qty Add
26986-1 Lysodren (mitotane - 1 Tab $6.99
26986-2 Lysodren (mitotane) - 100 Tab $549.00
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Technical Specs:
  • Lysodren Mitotane is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to use mitotane to treat Cushing’s disease in dogs.
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  • Lysodren Mitotane acts by suppressing adrenal gland function and treatment involves two phases. Lysodren is a cytotoxic drug. It has a predilection for killing cells in a particular zone of the adrenal gland, thereby reducing function of that part of the gland. This lowers the blood cortisol concentration.
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  • Mitotane decreases the production of cortisol but at therapeutic doses has minimal effects on other adrenal tissues or hormones such as aldosterone.
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  • Lysodren Side Effects: Side effects of mitotane may include Addison’s disease or symptoms that indicate the onset of Addison’s disease such as loss of appetite, vomiting, diarrhea , weakness and drowsiness. There may be a need to supplement with glucocorticoids such as prednisone if symptoms are observed.




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