Pyrantel Pamoate
(Pyrantel Pamoate)
Equine Anthelmintic Suspension
Description:
(Pyrantel Pamoate) is a suspension of pyrantel pamoate in a palatable vanilla-flavored vehicle. Each mL contains 50 mg of pyrantel base as pyrantel pamoate.
Pyrantel pamoate is a compound belonging to a family classified chemically as tetrahydropyrimidines. It is a yellow, water-insoluble crystalline salt of the tetrahydropyrimidine base and pamoic acid containing 34.7% base activity. The chemical name is: (E)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl) vinyl] pyrimidine 4, 41 methylenebis [3-hydroxy-2-naphthoate] (1:1).
Indications For Use:
For the removal and control of mature infections of large strongyles (Strongylus vulgaris, S. edentatus, S. equinus); pinworms (Oxyuris equi); large roundworms (Parascaris equorum); and small strongyles in horses and ponies.
Dosage and Treatment:
Administer 3 mg pyrantel base per pound of body weight (6 mL Pyrantel Pamoate per 100 lb body weight).
For maximum control of parasitism, it is recommended that foals (2-8 months of age) be dosed every 4 weeks. To minimize potential hazard that the mare may pose to the foal, she should be treated 1 month prior to anticipated foaling date followed by re-treatment 10 days to 2 weeks after birth of foal. Horses over 8 months of age should be routinely dosed every 6 weeks.
Directions For Use:
Pyrantel Pamoate may be administered by means of a dose syringe or by mixing into the feed.
Dose Syringe: Draw the appropriate dosage of Pyrantel Pamoate into a dose syringe and administer to the animal. Do not exposePyrantel Pamoate to direct sunlight.
Feed: Mix the appropriate dosage of Pyrantel Pamoate in the normal grain ration. Fasting of animals prior to or following treatment is not required.
This product is a suspension and as such will separate. To insure uniform re-suspension and to achieve proper dosage, it is extremely important that the product be shaken and stirred thoroughly before every use.
Efficacy:
Critical (worm-count) studies in horses demonstrated that pyrantel pamoate administered at the recommended dosage was efficacious against mature infections of Strongylus vulgaris (>90%), S. edentatus (69%), S. equinus (>90%), Oxyuris equi (81%), Parascaris equorum (>90%), and small strongyles (>90%).
Safety:
