Cushing's disease is the overproduction of the hormone cortisol by the adrenal glands that are located in the belly near the kidneys. Cushing's disease occurs commonly in dogs, but is rare in cats. Most dogs with Cushing’s disease are about 6 years old or older but sometimes Cushing's disease occurs in younger dogs. Cortisol affects the function of many organs in the body, so the signs of Cushing’s disease may be varied. Some of the more common signs of Cushing’s disease include hair loss, pot-bellied appearance, increased appetite, and increased drinking and urination. Hair loss caused by Cushing’s disease occurs primarily on the body, sparing the head and legs. Less common signs of Cushing’s disease are weakness, panting, and an abnormal way of walking. Some dogs with Cushing’s disease develop a blood clot to the lungs and show a rapid onset of difficulty breathing. Cushing's disease can be treated using Vetoryl, which improves dog's well-being and decreases the symptoms, and Selegiline, which also treats Cushing's disease.