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Cyclosporine (modified) 30 Capsules

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What is Cyclosporine (modified) 30 Capsules?
Cyclosporine capsules (generic to Atopica) is used to treat atopic dermatitis in dogs and control skin allergy symptoms such as scratching, licking, gnawing, skin infections and hair loss. These symptoms cause your pet to live in discomfort. Cyclosporine treats the allergy at the source and targets cells in the immune system that cause the allergic reactions in your pet.


Who is Cyclosporine (modified) 30 Capsules for?
Dogs (6 months or older)


Why use Cyclosporine (modified) 30 Capsules?
- Treats Atopica Dermatitis
- Keratoconjunctivitis Sicca (dry eye)
- Treats Immune-medicated Hemoltic Anemia


How Cyclosporine (modified) 30 Capsules work?
Unlike other medications of immune suppression which act by killing cells of the immune system, cyclosporine acts by interfering with helper T-lymphocyte interleukin production.


Generic Brands:
Atopica


Manufacturer:
Watson / Teva


Active ingredient(s):
Cyclosporine USP 25 mg


How is Cyclosporine (modified) 30 Capsules sold?
30 Capsules
25 mg, 50 mg, 100 mg


What are the side effects of Cyclosporine (modified) 30 Capsules?
The most common side effect seen with cyclosporine is upset stomach (appetite loss, vomiting, diarrhea, or all of these).


What special precautions are there?
Cyclosporine is a potent systemic immunosuppressant that may increase the susceptibility to infection and the development of neoplasia.
Notify your veterinarian immediately if your pet develops fever (over 103°), painful urination, tiredness, sneezing, coughing, or runny nose. These symptoms could be early signs of dangerous side effects.


What to do if overdose?
Contact your nearest emergency animal hospital.


How can I store Cyclosporine (modified) 30 Capsules?
Notify your veterinarian immediately if your pet develops fever (over 103°), painful urination, tiredness, sneezing, coughing, or runny nose. These symptoms could be early signs of dangerous side effects.


Helpful Tips:
While it’s not approved by the FDA for cats, it is commonly prescribed by veterinarians to treat Cats.


Cyclosporine is generally given once or twice daily depending on the disease being treated.

Dogs with atopic dermatitis begin with once daily usage and then taper to a schedule more like every other day or less.
Because the dose one swallows orally does not reliably produce a predictable blood level, therapeutic blood level monitoring is often recommended with oral cyclosporine use.
 
A blood cyclosporine level is usually checked a day or two into therapy and then every 2-4 weeks.  The lowest blood level of the day should be 100-500 ng/ml in dogs and 250-1,000 ng/ml in cats, though this in some part depends on the laboratory running the test. In using cyclosporine for the treatment of atopic dermatitis, blood levels are generally not monitored because it is the concentration of drug in the patient's skin (not the blood) which is pertinent and there is no way to measure skin levels of cyclosporine.
 
While it’s not approved by the FDA for cats, it is commonly prescribed by veterinarians to treat cats.  
Cyclosporine USP 100mg
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