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Propalin Dog Urinary & Kidney Medications
Propalin Item# 25944
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What is Propalin?
PROPALIN is recommended for the long-term management of urinary incontinence associated with urethral sphincter incompetence in spayed dogs.
We do not ship Propalin to Arkansas, Iowa, Louisiana and Oregon where it is classified as a controlled substance.

Who is Propalin for?

Why use Propalin?
- Effective treatment for urinary incontinence in dogs.
- Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability

How Propalin work?
Phenylpropanolamine is a chemical analogue of the endogenous sympathomimetic amines. It is an a-adrenergic agent which has been reported to increase resting urethal tone in dogs.1 It acts by direct stimulation of the smooth muscle of the internal urethral sphincter.

Generic Brands:


Active ingredient(s):
Phenylpropanolamine HCl

How is Propalin sold?
PROPALIN™ Tablets are supplied in 60 and 180 count bottles.

What are the side effects of Propalin?
Sympathomimetics may produce a wide range of effects, most of which mimic the results of excessive stimulation of the sympathetic nervous system. Side effects include anorexia, restlessness, irritability, tremors, tachycardia, cardiac arrhythmia, hypertension and urinary retention.

What special precautions are there?
May cause excitability and restlessness.

What to do if overdose?
Contact your veterinarian or veterinary emergency room. Symptoms of overdose (thyrotoxicosis) may include increased thirst, urination and hunger, hyperactivity, personality change, and reduced heat tolerance.

How can I store Propalin?
Store in a dry place below 25°C (77°F). Do not refrigerate.

Helpful Tips:
Dog bladder infections or incontinence can cause a strong urge to urinate and is a primary cause of canine urinary incontinence. Dogs with an infected bladder tend to empty the bladder partially each time that they urinate. This occurs due to a difficulty in emptying the entire urinary bladder in one go and makes the urine extremely smelly. The urine may sometimes contain blood due to severe infections caused by calculi, cancer, or a tumor.

Use as directed by your veterinarian.
Administer orally with food, 3 mg/kg B.W. per day, divided in 2 or 3 equal doses:


25 mg: For smaller dogs

Divided in 2 doses

1.5 mg/kg B.W. (1 PROPALIN™ 25 mg tablet/17 kg B.W. 1/2 tablet/8.3 kg B.W.) two times daily.

Divided in 3 doses

1.0 mg/kg B.W. (1 PROPALIN™ 25 mg tablet/25 kg B.W. 1/2 tablet/12.5 kg B.W.) three times daily.

50 mg: For medium dogs

Divided in 2 doses

1.5 mg/kg B.W. (1 PROPALIN™ 50 mg tablet/34 kg B.W. 1/2 tablet/17 kg B.W.) two times daily.

Divided in 3 doses

1.0 mg/kg B.W. (1 PROPALIN™ 50 mg tablet/50 kg B.W. 1/2 tablet/25 kg B.W.) three times daily.

75 mg: For larger dogs

Divided in 2 doses

1.5 mg/kg B.W. (1 PROPALIN™ 75 mg tablet/50 kg B.W. 1/2 tablet/25 kg B.W.) two times daily.

Divided in 3 doses

1.0 mg/kg B.W. (1 PROPALIN™ 75 mg tablet/75 kg B.W. 1/2 tablet/75 kg B.W.) three times daily.

If clinical response is poor, the initial diagnosis should be reconsidered.

For this drug to be effective, it must be administrated as directed. Missed doses will negate its effect.


Do not use in animals with pre-existing medical conditions (e.g. cardiovascular disease, hypertensive disease, renal insufficiency). Do not use in animals taking cardiovascular medications or any other sympathomimetic agents.




Lethargy and inappetence have been reported in a dog following an overdose (2.5 mg/kg three times daily).


Each chewable tablet contains either:

Phenylpropanolamine HCl 25 mg

Phenylpropanolamine HCl 50 mg

Phenylpropanolamine HCl 75 mg

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