DOSAGE AND ROUTE OF ADMINISTRATION
Phenylbutazone may be given orally or by the intravenous route. Oral preparations available include tablets (to be crushed and mixed with feed or given with a balling gun), paste, and gel forms.
The maximum manufacturer's recommended intravenous dose is 1-2 grams/1000 Ib daily. The upper dose limit is recommended for initial injection to achieve rapid control of the inflammatory process. This should then be decreased.
The maximum manufacturer's recommended oral dose is 2-4 grams/1000 Ib daily. Because blood levels drop rapidly, it is suggested that the total daily dose be divided and the drug be administered every 8 hours for best effect. Many veterinarians and owners get satisfactory results giving phenylbutazone only once or twice a day.
Phenylbutazone 1 g