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Health Article
Apoquel Tablet  Dog Allergy & Skin Medication
Apoquel Tablet Item# 25639
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Apoquel Tablet

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What is Apoquel Tablet?
Apoquel from Zoetis provides rapid relief of pruritus (itch) in dogs associated with allergic dermatitis and provides control of atopic dermatitis in dogs at least 12 months of age. Unlike common therapies such as steroids, cyclosporines or antihistamines, APOQUEL is the only treatment specifically designed to go straight to the source of the itch.


Who is Apoquel Tablet for?
Apoquel is for dogs older than 12 months of age


Why use Apoquel Tablet?
- Apoquel reduces inflammation in the skin similar to glucocorticoids
- Apoquel reliefs itch caused by flea allergy, food allergy, contact allergy and atopic dermatitis in dogs.
- APOQUEL targets the cause of the itch, it has minimal effect on other parts of the dog’s body


How Apoquel Tablet work?
- APOQUEL starts to relieve the itch within 4 hours, comparable to steroids.
- APOQUEL effectively controls the itch within 24 hours
- APOQUEL relieves itch in the long term.


Manufacturer:
Zoetis


Active ingredient(s):
APOQUEL tablets contain 3.6 mg, 5.4 mg, or 16 mg of oclacitinib as oclacitinib maleate per tablet. Each strength tablets are packaged in 20 and 100 count bottles. Each tablet is scored and marked with AQ and either an S, M, or L that correspond to the different tablet strengths on both sides.


What are the side effects of Apoquel Tablet?
In most cases, diarrhea, vomiting, anorexia, and lethargy spontaneously resolved with continued dosing.


What special precautions are there?
APOQUEL is not for use in dogs with serious infections.
APOQUEL may increase susceptibility to infection, including demodicosis, and exacerbate neoplastic
conditions (see Adverse Reactions and Animal Safety).
APOQUEL is not for use in breeding dogs, or pregnant or lactating bitches.
The use of APOQUEL has not been evaluated in combination with glucocorticoids, cyclosporine, or other
systemic immunosuppressive agents.
Dogs receiving APOQUEL should be monitored for the development of infections, including demodicosis,
and neoplasia.


What to do if overdose?
Contact your nearest emergency animal hospital.


How can I store Apoquel Tablet?
APOQUEL should be stored at controlled room temperature between 20° to 25°C (68° to 77°F) with excursions
between 15° to 40°C (59° to 104°F).


Helpful Tips:
APOQUEL can be used for dogs over 1 year of age to help lessen itch and inflammation due to allergic skin disease.
Unlike common therapies such as steroids, cyclosporines or antihistamines, APOQUEL is the only treatment specifically designed to go straight to the source of the itch. Since
APOQUEL targets the cause of the itch, it has minimal effect on other parts of the dog’s body, unlike some other drugs.


Warning: 

APOQUEL is not for use in dogs with serious infections.
APOQUEL may increase susceptibility to infection, including demodicosis, and exacerbate neoplastic conditions (see Adverse Reactions and Animal Safety).
 
Indications: Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.
APOQUEL comes in tablet form. You will need to give your dog 2 doses per day for up to 14 days. After 14 days, you will need to give your dog only 1 dose of APOQUEL per day.  
 
Dosage and Administration: The dose of APOQUEL (oclacitinib maleate) tablets is 0.18 to 0.27 mg oclacitinib/lb (0.4 to 0.6 mg oclacitinib/kg) body weight, administered orally, twice daily for up to 14 days, and then administered once daily for maintenance therapy. APOQUEL may be administered with or without food.
 
 
 
APOQUEL tablets contain 3.6 mg, 5.4 mg, or 16 mg of oclacitinib as oclacitinib maleate per tablet. Each strength tablets are packaged in 20 and 100 count bottles. Each tablet is scored and marked with AQ and either an S, M, or L that correspond to the different tablet strengths on both sides.
Average Product Rating:
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(4.78) Based On Reviews

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Showing comments 1-10 of 18 Comments | 1 2 Next
1. Anonymous on 4/9/2014 said:
1 2 3 4 5

I am have the same effects as the last post. My 3 yr old mix has been on it for approx 2 months. Started off with 2 pills a day for 2 weeks (which worked great)then down to one pill a day. Even though it does give him some relief it seems it has become less effective in the last 2 weeks. At least he is not chewing himself raw anymore but he does still itch several times a day. I will be contacting my vet to see if I can maybe give him 1 1/2 a day. With spring here I am hoping it doesnt get worse.
(0 people found this comment helpful, 0 did not)
2. Anonymous on 4/4/2014 said:
1 2 3 4 5

Good but not 100% effective. We rescued a dog who's had allergies since he was a puppy. He's now 6 years old. We have tried virtually everything. Elimination diet, skin testing, holistic healing, chinese herbs, herbal remedies, medicated/natural shampoos, skin treatments, supplements of all shapes and sizes. Atopica/cyclosporin did not work. The only effective treatment has only ever been steroids (methylprednisone, a relation to the more common prednisone). -------------------------------------------------------------------------------- So he's been on steroids for almost 6 years. We've tried to keep him on as low a dose as possible but have had to up it occasionally when his allergies seemed to be worse. Even the steroids, on the dosage we were giving him, were not 100% effective. -------------------------------------------------------------------------------- Enter Apoquel. I was so excited when I learned about this new drug that I actually started calling around my local vets to see who had it in stock. Took my dog in the next day. -------------------------------------------------------------------------------- The vet recommended 1 pill twice a day for 3-4 days, then down to 1 pill once a day. Note the manufacturer recommends 1 pill twice a day for 2 weeks. -------------------------------------------------------------------------------- We first had to ween our dog off the pred for a week so his itching flared up. We noticed a decrease in itching just hours after the first Apoquel pill was given. Note: pred provided this quick relief as well. -------------------------------------------------------------------------------- On 2 pills per day, we were in high heaven. No itching at all and no noticeable side effects. When we took him down to 1 pill on the 4th day per the vet recommendation, the itching flared up immediately. So the vet said we could keep him on 2 pills/day for up to 2 weeks. So we did that. -------------------------------------------------------------------------------- What a wonderful 2 weeks we had. No itching at all. But I had a feeling once we went down to 1 pill a day, things would get worse. -------------------------------------------------------------------------------- And that's basically what is happening. Our dog has been on 1 pill once a day for about 2 weeks and his itching is getting worse and worse. The 1st week on 1/day was fine. Very mild itching for a minute or 2 but nothing chronic. But we're now getting into the 3rd week on 1/day and his itching is increasing every day. Obviously, the Apoquel is losing its effectiveness at this lower dosage. If this continues, we're going to have to supplement with something else--maybe going back to 2 pills a day for a while or adding back pred, which I know is not really ideal. -------------------------------------------------------------------------------- I still give Apoquel a positive rating for now because, as I said, even pred was not 100% effective. In fact, Apoquel seems to be as effective as pred was on the dosage of pred we were giving (ie. about 60-80% effectiveness, it always fluctuates). But if the claims are true that Apoquel doesn't have the possible very negative side effects that steroids can have, then I'd still choose Apoquel -- because hey, it works just as well (or not as well) as steroids but without the harmful side effects. -------------------------------------------------------------------------------- Of course, Apoquel is a new drug and despite the trials, we're really not going to know what the REAL long-term side effects are for years and years after hundreds of thousands of dogs have been on it. (Think Rimadyl--bet everybody loved that drug at first.) -------------------------------------------------------------------------------- I just hope that Apoquel doesn't continue this trend of being less effective with my dog over time. My vet said, of the ~ 10 dogs they've seen so far who they've prescribed Apoquel to, 1/3 have had no relief, 1/3 have had some relief, and 1/3 have had great relief. So it's not really the "miracle drug" it's being touted as, but certainly, it's always wonderful to have another alternative, esp if your dog is one of the lucky 1/3.
(0 people found this comment helpful, 0 did not)
3. Anonymous on 3/23/2014 said:
1 2 3 4 5

This medicine is unbelievable. I have a 10 year old Golden Retriever that has suffered from itching and dermatitis for the last 2-3 years. I started this medication last week and within a day he completely stopped scratching. His skin and coat look awesome and no more irritations. Thank you Apoquel!!!!!!!!!!!!
(0 people found this comment helpful, 0 did not)
4. Anonymous on 3/21/2014 said:
1 2 3 4 5

My poodle has had skin problems since birth. All she did was itch, scratch, bite at her feet, scratch her ears, and scratch,scratch, scratch! Steroid shots helped some for a week or so, and I knew they were not good for her. She is only 6 years old. I gave her an Apoquel dose when I got home from the vet today and within a few minutes no scratching at all. It's been 12 hours now and still no scratching whatsoever! We, my dog and I, could not be happier!!!
(0 people found this comment helpful, 0 did not)
5. Anonymous on 3/16/2014 said:
1 2 3 4 5

Unbelievable medication. I have tried every med given by the vet and bought at the store for itching and nothing worked and then the miracle pill apoquel tablets..... I have my 10 year old pit/ mastiff back and itch free. He sleeps all night and his skin is awesome looking. Thank you for the makers of Apoquel.
(0 people found this comment helpful, 0 did not)
6. Anonymous on 3/15/2014 said:
1 2 3 4 5

Apoquel worked fast and with no side effects in our 5 year old Sheltie who developed allergies. Atopica was only 40% effective and caused occasional diarrhea and vomiting. Steroids were only effective for up to a week. Zyrtec, Benadryl, and modified diets did not provide any relief for her.
(0 people found this comment helpful, 0 did not)
7. Anonymous on 3/15/2014 said:
1 2 3 4 5

We have a 10 year old mixed breed who has been consumed by allergies the last few years. It got so bad it took away his spirit. We were very concerned about his future. We put him on apoquel and it has been 100% turnaround. We have our dog back. It's pricey but I could care less, it is well worth it and I will skip Starbucks to keep him on it.
(0 people found this comment helpful, 0 did not)
8. Anonymous on 3/12/2014 said:
1 2 3 4 5

Unbelievable improvement when steroids failed and made my male newfoundland sick.
(0 people found this comment helpful, 0 did not)
9. Anonymous on 3/10/2014 said:
1 2 3 4 5

This is great, after taking 1 tablet my dog stopped scratching herself. It was getting so bad that she scratched the fur right off her belly. This is something that she's gone thru every winter and nothing else helped. Great product but very pricy.
(0 people found this comment helpful, 0 did not)
10. Anonymous on 3/8/2014 said:
1 2 3 4 5

MIRACLE DRUG!!! My most wonderful dog has been plagued with itchy Florida skin her whole life. I've tried everything under the sun, spending thousands of dollars and the only thing that ever helped was Prednisone, which has SO many bad side effects, I couldn't keep her on it. I just started her on Apoquel and it has completely changed her. She is no longer constantly itching/licking/chewing herself to death. A must have for dogs with skin allergies!
(0 people found this comment helpful, 0 did not)
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