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Item No.
50858
Zycortal Suspension 25 mg/ml, 4 ml Vial Rx
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Zycortal Suspension 25 mg/ml, 4 ml Vial Description
Zycortal Suspension (Desoxycorticosterone Pivalate) is sold as an injectable treatment. It is used as a replacement therapy for deficiency of mineralocorticoid in dogs with Addison's disease (primary hypoadrenocorticism).
What is Zycortal Suspension 25 mg/ml, 4 ml Vial?
It is an injectable for use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s Disease).
Which animals/pets is Zycortal Suspension 25 mg/ml, 4 ml Vial for?
For use in dogs.
Zycortal Suspension 25 mg/ml, 4 ml Vial uses
Zycortal Suspension (Desoxycorticosterone Pivalate) is used in the treatment of Addison's disease (hypoadrenocorticism).
What does Zycortal Suspension 25 mg/ml, 4 ml Vial do?
Features of Zycortal:
- It is a corticosteroid with primarily mineralocorticoid activity, which is similar to aldosterone.
- It causes chloride iron and sodium retention in the kidneys and causes excretion of potassium and hydrogen ion, which creates a water absorbtion-promoting osmotic gradient in the renal tubules. This increases the volume of extracellular fluid, which leads to an increase of cardiac output, an improvement in venous return to the heart, and expansion of blood volume.
Zycortal Suspension 25 mg/ml, 4 ml Vial side effects
Zycortal is proven to be well-tolerated with infrequent reports of adverse reaction. However, in a small percentage of dogs, the following side effects could present:
- Reactions at the injection site, such as abscesses or pain
- Weakness
- Changes in coat or skin
- Digestive changes
- Excessive urination or thirst
- Depression
- Cardiac enlargement
- Edema (swelling)
- Increase in blood volume
Zycortal Suspension 25 mg/ml, 4 ml Vial ingredients
Desoxycorticosterone Pivalate
Zycortal Suspension 25 mg/ml, 4 ml Vial overdose: What to do?
Contact your closest emergency pet hospital
What to know before using Zycortal Suspension 25 mg/ml, 4 ml Vial
- Safety of Zycortal has not been proven in treating puppies under 6 months old or lactating, pregnant, or breeding dogs.
- Fluid retention caused by sodium retention can cause excessive weight gain.
- Exercise caution when administering to dogs with primary hepatic failure, severe renal disease, edema, or congestive heart disease.
- Zycortal effectiveness may be affected if potassium-sparing diuretics (like spironolactone) are administered concurrently.
- Avoid injecting intravenously. This may have cause an adverse reaction.
- Dogs with inadequate tissue perfusion (Addisonian crisis), prerenal azotemia, dehydration, or severe hypovolemia (blood volume depletion) should be rehydrated using intravenous fluid therapy (saline) prior to starting Zycortal treatment.
- Do not administer to dogs with prior hypersensitivity to desoxycorticosterone pivalate.
How is Zycortal Suspension 25 mg/ml, 4 ml Vial sold?
25 mg/ml, 4 ml vial
Manufacturer
Dechra
Tips for using Zycortal Suspension 25 mg/ml, 4 ml Vial
Addison's disease is often referred to as "the great pretender" because it can be difficult to recognize and diagnose. Once it is suspected, a simple ACTH test can confirm the diagnosis. Pet parents should research the signs and symptoms of Addison's disease and inform their pet's veterinarian if they exhibit these symptoms.
Overview
Use as directed by your veterinarian.
Main Ingredients
Desoxycorticosterone Pivalate
