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Mastitis is the inflammation of the mammary gland and udder tissue, and is a major endemic disease of dairy cattle. It usually occurs as an immune response to bacterial invasion of the teat canal by variety of bacterial sources present on the farm, and can also occur as a result of chemical, mechanical, or thermal injury to the cow's udder. J-5 E. coli bacterin, a vaccine sold on Allivet, is intended for use in conjunction with appropriate management practices to help prevent coliform mastitis in cows, goats, sheeps and pigs. 
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