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The equine esophagus extends into the first one-third of the stomach, making horses susceptible to acid-reflux disease. Naturally present bacteria can colonize in ulcers, and the stomach acid can keep them from healing. Gastric Ulcers and Colitis are common in horses, and they should be treated early on in order to prevent complications and more serious issues in your horse. There are many treatments for gastric ulcers are colitis, like GastroGard and Misoprostol Tablets.