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Item No.
32483
Prascend Tablets 1 mg Rx
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Prascend Tablets 1 mg Description
PRASCEND® (pergolide tablets) is the most proven treatment available to control the clinical signs associated with PPID in horses (formerly known as equine Cushing’s disease).1 PRASCEND is a rectangular light red colored, half-scored tablet containing 1 mg pergolide, as pergolide mesylate, a dopamine receptor agonist for oral use in horses only.1
1. PRASCEND® (pergolide tablets) [Freedom of Information Summary]. St Joseph, MO: Boehringer Ingelheim Vetmedica, Inc.; 2011.
What is Prascend Tablets 1 mg?
PRASCEND® controls the clinical signs associated with Pituitary Pars Intermedia Dysfunction (Equine Cushing’s Disease) in horses.
Which animals/pets is Prascend Tablets 1 mg for?
For use in horses.
Prascend Tablets 1 mg uses
By using PRASCEND® (pergolide tablets) to treat PPID (Pituitary Pars Intermedia Dysfunction), you can help to ease the symptoms of PPID and improve the horse’s overall quality of life.
Benefits include:
*An improvement in clinical signs within 3 months and continued improvement through 6 months1
*A study showed that 3 or 4 horses treated were PRASCEND® were treatment successes1
*89% of treated horses showed improvement in hypertrichosis (delayed shedding) within 6 months1
1. PRASCEND® (pergolide tablets) [Freedom of Information Summary]. St Joseph, MO: Boehringer Ingelheim Vetmedica, Inc.; 2011.
What does Prascend Tablets 1 mg do?
Pergolide mesylate is a synthetic ergot derivative and is a potent dopamine receptor agonist.
Prascend Tablets 1 mg side effects
To read more about possible side effects, please review the package insert.
Prascend Tablets 1 mg ingredients
Pergolide, as pergolide mesylate
Prascend Tablets 1 mg overdose: What to do?
Contact your closest emergency pet hospital.
What to know before using Prascend Tablets 1 mg
Treatment with PRASCEND® (pergolide tablets) may cause inappetence. The use of PRASCEND in breeding, pregnant, or lactating horses has not been evaluated. The effects of pergolide mesylate on breeding, pregnant, or lactating horses are not known; however, the pharmacologic action of pergolide mesylate suggests that it may interfere with reproductive functions such as lactation.
PRASCEND is approximately 90% associated with plasma proteins. Use caution if administering PRASCEND with other drugs that affect protein binding. Dopamine antagonists, such as neuroleptics (phenothiazines, domperidone) or metoclopramide, ordinarily should not be administered concurrently with PRASCEND (a dopamine agonist) since these agents may diminish the effectiveness of PRASCEND. Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses. Adverse reactions may occur if animals other than horses ingest PRASCEND tablets. PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives. PRASCEND® (pergolide tablets) has not been evaluated in breeding, pregnant or lactating horses. Treatment with PRASCEND may cause loss of appetite. Most cases are mild. If severe, a temporary dose reduction may be necessary. PRASCEND tablets should not be crushed due to the potential for increased human exposure. Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses. Adverse reactions may occur if animals other than horses ingest PRASCEND tablets. Refer to the package insert for complete product information.
How is Prascend Tablets 1 mg sold?
PRASCEND® (pergolide tablets) are available in 1 mg strength – packaged 10 tablets per blister and 60 or 160 tablets per carton.
Manufacturer
Boehringer Ingelheim
Tips for using Prascend Tablets 1 mg
Speak with your veterinarian to determine if Prascend® is a good option for your horse.
Overview
Administer PRASCEND® (pergolide tablets) orally at a starting dose
of 2 mcg/kg once daily. Dosage may be adjusted to effect, not to exceed 4
mcg/kg daily. The tablets are scored and the calculated dosage should be
provided to the nearest one-half tablet increment.
DOSING TABLE
Body Weight 2 mcg/kg Dosage 4 mcg/kg Dosage
- 130-340 kg (300-749 lb) 2mcg/kg Dosage 0.5 tablet. 4 mcg/Kg Dosage 1 tablet.
- 341-567 kg (750-1,249 lb) 2mcg/kg Dosage 1 tablet. 4 mcg/Kg Dosage 2 tablets.
- 568-795 kg (1,250-1,749 lb) 2mcg/kg Dosage 1.5 tablets. 4 mcg/Kg Dosage 3 tablets
- 796-1,022 kg (1,750-2,249 lb) 2mcg/kg Dosage 2 tablets. 4 mcg/Kg Dosage4 tablets
Main Ingredients
Prascend Tablets are rectangular light red colored, half-scored tablets containing 1 mg pergolide, as pergolide mesylate.
Pergolide mesylate is a synthetic ergot derivative and is a potent dopamine receptor agonist. The chemical name of pergolide mesylate is 8β-[(Methylthio) methyl]-6-propylergoline monomethanesulfonate.