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Zycortal Suspension 25 mg/ml, 4 ml Vial Rx

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Product Description

Zycortal Suspension (Desoxycorticosterone Pivalate) is an injectable for use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s Disease). 

What is Zycortal Suspension 25 mg/ml, 4 ml Vial?

It is an injectable for use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s Disease).

Who is Zycortal Suspension 25 mg/ml, 4 ml Vial for?

Dogs

Why use Zycortal Suspension 25 mg/ml, 4 ml Vial?

-Treats Addison's Disease

How does Zycortal Suspension 25 mg/ml, 4 ml Vial work?

Desoxycorticosterone is a corticosteroid with primarily mineralocorticoid activity, similar to aldosterone. In the kidney, desoxycorticosterone causes sodium and chloride ion retention, and hydrogen and potassium ion excretion, creating an osmotic gradient that promotes water absorption from the renal tubules. This increases extracellular fluid volume, leading to blood volume expansion, improved venous return to the heart, and increased cardiac output.

Manufacturer:

Dechra

Active ingredient(s):

Desoxycorticosterone Pivalate

How is Zycortal Suspension 25 mg/ml, 4 ml Vial sold?

25 mg/ml, 4 ml vial

What are the side effects of Zycortal Suspension 25 mg/ml, 4 ml Vial?

It has been demonstrated that Desoxycorticosterone Pivalate Injectable Suspension is well tolerated with a low incidence of side effects. In a small percentage of treated dogs, depression, excessive thirst and urination, digestive, skin and coat changes, weakness, and injection site reactions (pain, abscesses) may occur. Some of these effects may resolve with adjustments in dose or interval or concomitant glucocorticoid administration. Do not use in pregnant dogs or in dogs that are suffering from congestive heart disease, severe renal disease, or edema.

What special precautions are there?

Do not use Zycortal Suspension in dogs that have previously had a hypersensitivity reaction to desoxycorticosterone pivalate. CAUTIONS: Any dog presenting with severe hypovolemia, dehydration, pre-renal azotemia and inadequate tissue perfusion (“Addisonian crisis”) must be rehydrated with intravenous fluid (saline) therapy before starting treatment with Zycortal Suspension. Avoid inadvertent intravenous injection which may have an adverse effect on the dog. The effectiveness of Zycortal Suspension may be reduced if potassium-sparing diuretics, such as spironolactone, are administered concurrently. Use Zycortal Suspension with caution in dogs with congestive heart disease, edema, severe renal disease or primary hepatic failure. Desoxycorticosterone pivalate may cause polyuria, polydipsia, increased blood volume, edema and cardiac enlargement. Excessive weight gain may indicate fluid retention secondary to sodium retention. The safety of desoxycorticosterone pivalate has not been established in breeding, pregnant and lactating dogs and dogs less than 6 months of age.

What to do if overdose?

Contact your nearest emergency animal hospital

How can I store Zycortal Suspension 25 mg/ml, 4 ml Vial?

Store between 15-30°C. Do not freeze. Use within 120 days of first puncture.

Helpful Tips:

Pharmacists are standing by to offer Pet Parent counseling regarding prescription medication purchased from Allivet before and after dispensing. Pharmacists on duty are available Monday-Friday, 9:30AM - 5:30PM EST and will be on call Saturday 12:00PM - 4:00PM EST for consultation.

Use as directed by your veterinarian.

Desoxycorticosterone Pivalate

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Zycortal Suspension 25 mg/ml, 4 ml Vial

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