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Combiva II for Cats

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Product Overview

How To Use

What’s in it?


Questions & Answers

Product Description

Combiva II for Cats is a once-monthly, spot-on, topical flea treatment that provides broad-spectrum coverage. It kills flea eggs, flea larvae, and adult fleas. It is effective in preventing reinfestation, preventing development of larvae and eggs into adults, and breaking the flea life cycle.
Comes in a three-dose, three-month supply based on your cat's weight.

Who is Combiva II for Cats for?

For use on kittens (ages 8 weeks and up; 2 pounds and up) and cats.

Why use Combiva II for Cats?

Features of Combiva II for Cats:
  • Easy- and convenient-to-apply, topical, once-monthly treatment
  • Product is waterproof once applied
  • Contains the same active ingredients as some of the more expensive, name-brand treatments
  • Breaks the lifecycle of the flea, preventing re-infestation and development of larvae and eggs into adults
  • Effective in killing eggs, larvae, and adult fleas

How does Combiva II for Cats work?

This effective treatment contains two active ingredients, pyriproxyfen and imidacloprid, that work together to kill adult fleas and prevent re-infestation. These effective ingredients break the life cycle of fleas, preventing larvae and eggs from growing into biting adults.



Active ingredient(s):

Imidacloprid 9.10%
Pyriproxyfen 0.46%

How is Combiva II for Cats sold?

3 monthly supply based on your cat's weight.
  • 5-9 lbs
  • Over 9 lbs

What are the side effects of Combiva II for Cats?

  • Rarely, sensitivities can occur following use of any type of pesticide in cats. If such symptoms are persistent or worsening, notify your veterinarian.
  • Cats should be monitored following application. While adverse reactions are rare, cats can experience transient application site irritation such as discomfort, scratching, or redness. If these or any other reactions occur, call 1-800-999-0297 or notify your veterinarian.
  • If you notice any unusual reactions following the first application, speak to your veterinarian prior to applying another dose.
  • Gastrointestinal effects like diarrhea, vomiting, and hypersalivation can occur.

What special precautions are there?

  • In case of clothing or skin contact, wash using plenty of soap and water. Contaminated clothing should be removed and washed prior to reuse.
  • In case of eye contact, hold the eye open, then slowly, gently rinse for 15 to 20 minutes with water. If contact lenses are present, remove them after 5 minutes of flushing and proceed with rinsing the eye. Contact a doctor or poison control center for advice regarding treatment.
  • In case of accidental swallowing of this product, contact a doctor or poison control center right away to seek advice regarding treatment. If the person can swallow, they should take sips of water. Never induce vomiting unless so directed by a doctor or poison control. Never administer anything by mouth to a person who is unconscious.
  • If your cat is nursing, pregnant, aged, debilitated, or taking any other medication, discuss these with your veterinarian prior to use of any pesticide, including this product.
  • Never treat a cat with multiple pesticides simultaneously.
  • Not for use in kittens under the age of 8 weeks or under 2 pounds.
  • Not for use on dogs.
  • Only for external application to cats.
  • After applying or handling, thoroughly wash hands using soap and water prior to using the bathroom, using tobacco, chewing gum, drinking, or eating.
  • Do not allow clothing or eye contact.
  • Mild irritation can occur if contact is made with eyes.
  • Swallowing this product is harmful.
  • Keep out of reach of animals and children.

What to do if overdose?

Contact your closest emergency pet hospital.

How can I store Combiva II for Cats?

Store in a dry and cool environment.


Simply open one of the enclosed tubes, then part the hair on the neck at the base of the skull of your cat until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents of the tube directly on the skin. Do not get this product in your cat’s eyes or mouth. The product is bitter tasting and salivation may occur for a short time if the cat licks the product immediately after treatment. Treatment at the base of the skull will minimize the opportunity for the cat to lick the product. Re-apply monthly as needed. 

Main Ingredients

Active Ingredients:
Imidacloprid – 9.10%
Pyriproxyfen – 0.46%

Other Ingredients: 90.44%
Total – 100.00%

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Combiva II for Cats

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