Sentinel vs Heartgard Plus

Pet parents are always striving to make the best choices for their dogs. That’s why heartworm prevention parasite treatment(s) are so important. With all the unique, high-quality, and impressive products available, it might be hard to decide which is best for your dog. Two of the best-loved products are Sentinel and Heartgard Plus.Both treatments offer safe and reliable protection, but there are many differences that set them apart from one another. Keep reading for information that could help you choose the right formula for your dog.

What makes Sentinel and Heartgard Plus different from one another?

These two products share a number of similarities. For starters, they are both chewable tablets, and they are both formulated to be administered to your dog monthly. Both formulas are safe for use in breeding or pregnant females, and Sentinel is also safe for lactating females. They both require a prescription from your veterinarian.

Both products are safe for use in puppies. Heartgard Plus can be used from an age of 6 weeks, while Sentinel is safe from 4 weeks and up. Both products prevent heartworm disease, and they are both effective against roundworms and hookworms.

There are also some differences between these treatment options. Heartgard Plus contains Pyrantel Pamoate and Ivermectin, while Sentinel combines Lufenuron with Milbemycin Oxime. Sentinel offers added protection against flea larvae and eggs, stopping their development and ending the flea life cycle. It is not effective against existing infestations. Sentinel also combats whipworms.

How do I make a decision between Sentinel and Heartgard Plus?

To choose between these medications, there are a few factors to consider. If you plan to treat a puppy between the ages of 4 and 6 weeks, you’ll want to choose Sentinel. If your dog is lactating or needs flea, hookworm, and whipworm protection, Sentinel is a great choice. You truly can’t go wrong with either of these top-quality treatment options.

Now that you’ve familiarized yourself with these products, it’s time to schedule an appointment with your veterinarian. With your vet, you’ll weigh these options, talk about your dog’s medical history, and address any concerns you might have before choosing the right treatment for your dog. If you have any lingering questions, reach out to the Allivet pharmacists for a pet parent consultation!

Sentinel for Dogs

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Feature Sentinel Heartgard Plus
Kills Fleas No No
Repels Fleas No No
Kills Flea Eggs and Larvae Stops development No
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Roundworms, Whipworms, and Hookworms Hookworms and roundworms
Waterproof Yes since taken orally Yes since taken orally
How Long to work Breaks cycle of fleas and eggs. Does not kill existing flea infestation. N/A
Taste Savory Beef Beef flavored
Active Ingredient Milbemycin Oxime and Lufenuron Ivermectin and Pyrantel Pamoate
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age Dogs 4 weeks and older Dogs 6 weeks and older
Manufacturer Virbac Boehringer Ingelheim
Safety Breeding, pregnant, and lactating dogs may use. Safe for pregnant or breeding females.