Laminitis is a disease that affects the feet of ungulates. It is best known in horses and cattle. Clinical signs of horse laminitis include lameness, inflammation, and increased temperature in the hooves. Horse Laminitis is a painful disease that should be treated as fast as possible in order to relieve the horse from pain and prevent the disease from progressing. Treatments for Horse laminitis include Isoxsuprine, which also helps improve the circulation in horses, and Predef, which has been found useful in alleviating the the pain associated with lameness in horses.