Product Page

Heartgard Plus Chewables For Dogs Rx

Heartgard Plus for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae for a month (30 days) after infection and for the treatment and control of ascarids and hookworms. See the Allivet Heartworm Comparison chart to find which heartworm prevention is best for your pet.

Please confirm

This item is already on your autoship schedule! Are you sure you want to add it again?
  • Autoship

Other Users also bought these products

What is Heartgard Plus Chewables For Dogs?

Heartgard plus prevents canine heartworm disease, and also treats parasites such as roundworms and hookworms in dogs.

Who is Heartgard Plus Chewables For Dogs for?

Dogs and puppies over 6 weeks of age. Safe for pregnant/breeding females.

Why use Heartgard Plus Chewables For Dogs?

-Protect your dog from heartworm disease
-Treat and control hookworms and roundworms
-Delicious beef-flavored chewable is easy to administer

How Heartgard Plus Chewables For Dogs work?

Heartgard Plus contains two active ingredients: ivermectin, which interferes with the parasite's nerve transmission, causing paralysis and death of the immature heartworms (larvae), and pyrantel pamoate, which also interferes with the parasite's nerve transmission, causing paralysis and death of intestinal worms.

Generic Brands:

Tri-Heart Plus and Iverhart Plus



Active ingredient(s):

Pyrantel Pamoate

How is Heartgard Plus Chewables For Dogs sold?

What are the side effects of Heartgard Plus Chewables For Dogs?

HEARTGARD is well tolerated. In rare cases vomiting or diarrhea within 24 hours of dosing was observed (1.1% of administered doses). The following adverse reactions have been reported following the use of HEARTGARD: Depression/lethargy, vomiting, anorexia, diarrhea, mydriasis, ataxia, staggering, convulsions and hypersalivation.

What special precautions are there?

All dogs should be tested for heartworm infection before starting a preventive program.
Do not give Heartgard Plus to your pet if already taking another heartworm medication.

What to do if overdose?

Contact your nearest emergency animal clinic.

How can I store Heartgard Plus Chewables For Dogs?

Store between 68°F - 77°F (20°C - 25°C).
Excursions between 59°F - 86°F (15°C - 30°C) are permitted. Protect product from light.

Helpful Tips:

It is important to eliminate fleas on the pet and in the household and to not feed the pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

Pharmacists are standing by to offer Pet Parent counseling regarding prescription medication purchased from Allivet before and after dispensing. Pharmacists on duty are available Monday-Friday, 9:30AM - 5:30PM EST and will be on call Saturday 12:00PM - 4:00PM EST for consultation.

HEARTGARD Plus should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms.                                                                                                                                             

 Dog                           Chewables            Ivermectin            Pyrantel                Color Coding on Foil Backing
Weight                        Per Month              Content                Content                             and Carton

Up to 25 lb                         1                        68 mcg                   57 mg                                     Blue

26 to 50 lb                          1                       136 mcg                114 mg                                   Green

51 to 100 lb                        1                       272 mcg                227 mg                                   Brown

Heartgard Blue Chewables (for Dogs 1-25 lbs):
Active Ingredient / Amount
Ivermectin               68 mcg
Pyrantel                    57 mg
Heartgard Green Chewables (for Dogs 26-50 lbs):
Active Ingredient  Amount
Ivermectin            136 mcg
Pyrantel                114 mg
Heartgard Brown Chewables (for Dogs 51-100 lbs):
Active Ingredient  Amount
Ivermectin            272 mcg
Pyrantel                227 mg
On the way to a Healthy Canine heart
Keep your dog's heart healthy

Pet owners may not realize that heart disease is a fairly common condition in dogs just as in humans.  Although heart disease mostly affects older dogs, it doesn’t hurt to think about preventative care even if your dog is still a puppy.  There are important steps dog owners can take even in the early years that will help maintain your dog’s heart health.


A small percentage of dogs are afflicted with a heart condition since birth.  A congenital heart condition happens when a dog is born with a cardiac abnormality which needs to be corrected.  Most heart disease, however, is acquired.  This means that dogs usually are not born with heart trouble, but develop it over the years.  There are certain aspects of your dog’s life which can influence the health of his heart.  It’s good to start healthy habits early so that your dog will live a longer and better life in the later years. Regular trips to the animal clinic, a nutritious diet, and proper exercise are factors which can help keep your dog’s heart healthy.


The first step is to make yearly check-ups at the animal clinic.  Your dog’s veterinarian will check for heart disease during the annual physical exam.  In the early stages of heart disease, symptoms are difficult for pet owners to recognize.  The symptoms are often well-masked when heart trouble starts.  Some symptoms of heart disease like coughing, sneezing, weakness, weight loss and wheezing could be indicative of other illnesses which can confuse matters.  A veterinarian is more likely to pick up on the beginning stages of this disease.  A thorough exam will include listening to the heart, looking at the gums, finding possible organ swelling and checking the pulse.  With early detection, canine heart disease is generally easier to treat before it has a chance to progress too far.  The veterinarian will also suggest a heartworm test to ensure that your dog is not affected by this specific cardiac disease.  Once the heartworm test comes back negative, then it is essential that you begin giving your dog a heartworm preventative medication such as Heartgard, Trifexis, Interceptor, or revolution. These medications will prevent your dog from developing heartworm disease.


If the veterinarian does suspect that your dog has acquired heart disease, some further testing will be recommended.  Some tests the veterinarian may suggest are chest x-rays, blood and urine tests, an electrocardiogram (ECG) and/or an ultrasound.  These procedures will give the veterinarian a better idea of how far the heart disease has progressed and which treatments would best suit your dog’s condition.  


Ensuring that your dog receives a healthy, nutritious diet is another important part of canine heart health.  Just as in humans, obesity is a leading factor in the development of heart disease in dogs.  There are many different types of dog food to choose from these days, so ask your veterinarian which type would be best for your dog.  It’s important to not give your dog too many extras treats and people food.  If you and the veterinarian decide to change your dog’s diet, be sure to do it gradually in order to avoid stomach problems.  Some good dog food choices which help control heart disease are Purina CV CardioVascular Formula.


Another essential component in maintaining your dog’s health is exercise.  Obesity in dogs does not only come from poor diet choices, it also happens when a dog is not properly active.  Making time for walks and for active play daily will help in strengthening your dog’s heart and overall health.  Even if you have a hectic schedule, you can arrange to have a neighbor, a friend or a dog walker take your dog out for daily walks.  Receiving proper exercise will make your dog happier and give her a better chance of living longer.


Along with a modified diet and a proper exercise routine, the veterinarian will most likely prescribe medication if your dog is diagnosed with heart disease.  Which medications will depend on what type of heart disease your dog has.  Some of the more commonly prescribed medicines for dogs are Vetmedin (Pimobendan), Benazepril hydrochloride  (Brand Lotensin), AMLODIPINE, Norvasc, Digoxin, and Spironolactone.


Without proper treatment, heart disease will eventually lead to heart failure.  This occurs when the heart becomes too weak and damaged to pump enough blood to meet the body’s needs.  When a dog suffers from heart failure, the other organs in the body feel a tremendous strain and can’t work efficiently.  When heart disease becomes this advanced, a dog will have trouble getting comfortable, have decrease in appetite and be extremely weak.


If your dog is suffering from heart disease, there is the option of a cardiac specialist.  This type of specialist will be able to offer the latest treatments available for dogs with heart conditions.  Ask your dog’s veterinarian for information about this option or for a referral.


There are steps you can take to improve your dog’s heart health.  Routine trips to the animal clinic, healthy eating habits, adequate exercise will all help lead to a healthy heart.  Watch out for the signs of heart trouble which include coughing, sneezing, difficulty breathing, and weight loss.  If your dog is diagnosed with heart disease or failure, be sure to follow the veterinarian’s recommendations.  If you feel your dog needs more specialized care than seek the advice of a canine cardiologist.  It’s essential to take care of your dog’s heart now so that you will be able to enjoy more years together in the future.   

Talk to other pet lovers about this product.

1 Questions | 1 Answers
Questions With Most helpful Answers?

Is Heartgard made in America?1 Answer

Is Heartgard made in America?1 Answer

1 Months ago
, From New Jersey


Yes. It is made in USA.
1 Months ago
Allivet Contributor
Thank you for your feedback.

From the makers of Heartgard Plus Chewables For Dogs

Alternative Products

Reviews 134

Tri-Heart Plus Rx

Starts at$18.99
In Stock

Follow Us

For exclusive coupons and giveaways!