Protection Made for Every Dog
One Chew, Triple Protection
Simparica Trio is the #1 veterinarian-prescribed combination parasite control product1 that protects your dogs against three categories of parasites.
Simple Monthly Protection
One chew helps protect your dog from multiple parasites, including fleas, ticks, heartworm disease, and common intestinal worms.
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Broad Protection in One Monthly Chew
Ticks
Kills six types of ticks, including deer ticks that may carry Lyme disease.
Heartworm Disease
One monthly dose helps protect dogs against heartworm disease.
Fleas
Starts killing fleas before they can lay eggs in your home.
Intestinal Worms
Helps treat and control common intestinal worms.
IMPORTANT SAFETY INFORMATION
Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information at SimparicaTrioPI.com.
†For the treatment and control of the Gulf Coast Tick (Amblyomma maculatum), Deer Tick (Ixodes scapularis), American Dog Tick (Dermacentor variabilis), Lone Star Tick (Amblyomma americanum), Brown Dog Tick (Rhipicephalus sanguineus), and Asian Longhorn Tick (Haemaphysalis longicornis). ‡Studies to support FDA approval showed that 1 dose provided 100% protection against heartworm disease. §Simparica Trio starts killing fleas within 4 hours. #For the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina) and hookworm (L4, immature adult, and adult Ancylostoma caninum and adult Uncinaria stenocephala) infections. Indicated for the prevention of Dipylidium caninum (tapeworm) infections by killing fleas.
REFERENCES
*Data on file. ZMR: Kynetec PetTrack US FTH National Data January 10, 2025. **Simparica Trio - 15M Dogs and Counting, PetTrak Kynetec Veterinary Channel Review Q4, 2024. ††Study A161C-US-15-634. Data on file. Zoetis Inc.
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