Skip header
Free Shipping Over $49

As an essential business, we are open and shipping as usual!

My ProfileMy OrdersMy AutoShipMy RxMy PetsMy VetsMy RewardsSign In

Knockout E.S. Area Treatment

4.81 out of 5 stars
This Item Ships FREE!
Save 5% on your 1st AutoShip order and 5% on all future AutoShip orders

Please confirm

This item is already on your autoship schedule! Are you sure you want to add it again?

Product Overview

How To Use

What’s in it?


Questions & Answers

Product Description

Virbac Knockout E.S. Area Treatment contains pyriproxyfen, a regulator of insect growth. It prevents the development of flea infestations and kills any active infestations. See Allivet's Flea and Tick chart to find which flea and tick product is best for your pet.

*This product cannot be shipped to AK or HI.

Who is Knockout E.S. Area Treatment for?

For use in cats and dogs.

Why use Knockout E.S. Area Treatment?

Features of Knockout E.S. Area Treatment:
  • Treats homes and areas as large as 2,100 square feet
  • Should only be applied to cloth-upholstered areas and carpet
  • Kills active infestations of fleas
  • Prevents re-infestation for as long as 7 months

How does Knockout E.S. Area Treatment work?

This spray product kills active tick and flea infestations, prevents development of flea infestations, prevents reinfestation for up to 7 months, and contains Nylar® to regulate insect growth.


Virbac Animal Health

Active ingredient(s):

Pyriproxyfen: 2-[1-Methyl-2- [4-phenoxyphenoxy] ethoxy] pyridine, Pyrethrins, N-octyl bicycloheptene dicarboximide, and Permethrin.

How is Knockout E.S. Area Treatment sold?

16 oz

What are the side effects of Knockout E.S. Area Treatment?

No known side effects

What special precautions are there?

  • This product is extremely flammable. Keep away from heated surfaces, sparks, and fire. Do not expose to temperatures above 130°F, as this could cause the container to burst.
  • Contents are under pressure. Do not incinerate or puncture container.
  • Do not contaminate feed, food, or water by disposal or storage.
  • Apply this product only as directed on the label.
  • Drift from treatment areas could be hazardous to organisms in adjacent bodies of water.
  • This product is toxic to birds and fish. Do not apply directly to water, in areas where surface water is present, or in intertidal areas below the average high water mark.
  • Avoid contamination of feedstuffs or food.
  • Harmful if absorbed through the skin, inhaled, or swallowed.
  • Do not breathe spray mist or vapors.
  • Avoid contact with eyes or skin. If contact occurs, flush with copious amounts of water. Wash with warm water and soap following use. If irritation continues, seek medical attention.

What to do if overdose?

Contact your closest animal hospital.

How can I store Knockout E.S. Area Treatment?

Store in a dry and cool environment.

Helpful Tips:

This spray is an excellent choice for use in:
  • Industrial buildings
  • Commercial buildings
  • Veterinary clinics
  • Utilities
  • Warehouses
  • Transportation equipment, including trucks, trains, ships, boats, and buses
  • Supermarkets
  • Schools
  • Motels
  • Offices
  • Kennels
  • Hotels
  • Hospitals
  • Homes
  • Automobiles
  • Apartments


Use VIRBAC KNOCKOUT® extra strength Area Treatment at the rate of 16 oz for up to 2100 sq ft (8 oz for up to 1000 sq ft). Carpeted areas may be vacuumed before treatment and after treatment has dried. Treat infested areas or areas which could be infested; these include rugs, carpets, upholstered furniture, pet beds and pet resting areas. Hold can at arm's length and direct spray toward the areas to be treated. Use a sweeping motion to apply product and back away from treated area while holding the can 36 inches away from the surface being treated. Area of 80-100 sq ft can be treated in approximately 10 seconds with VIRBAC KNOCKOUT® extra strength Area Treatment.

Main Ingredients

Pyriproxyfen: 2-[1-Methyl-2- [4-phenoxyphenoxy] ethoxy]pyridine
N-octyl bicycloheptene dicarboximide

Write a Review

Knockout E.S. Area Treatment

Ask a New Question

Don’t know something or can’t find the information you are looking for? Ask us a question!

*Required Fields
We will ONLY use your email to notify you in regards to your submission.Privacy StatementQuestions & answers are typically posted within 24 hours, pending approval.