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Frontline Plus for Cats and Kittens

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Product Overview

How To Use

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Questions & Answers

Product Description

Frontline Plus for Cats and Kittens is a once-monthly topical tick and flea preventative medication that works to kill 100% of mature adult fleas on your kitten or cat in under twelve hours. It also kills 100% of chewing lice and ticks within 48 hours of application. Frontline Plus contains S-methoprene, which is an IGR (insect growth regulator) that kills flea larvae and eggs. It works to kill all stages of deer ticks (the primary carrier of Lyme disease), lone star ticks, American dog ticks, and brown dog ticks. See Allivet's Flea and Tick chart to find which flea and tick product is best for your pet.

Who is Frontline Plus for Cats and Kittens for?

For use in kittens (ages 8 weeks and up, weighing a minimum of 1.5 pounds) and cats.

Why use Frontline Plus for Cats and Kittens?

Features of Frontline Plus for Cats and Kittens:
  • Easy to use
  • Waterproof
  • Long-acting
  • Acts quickly
  • Safe for use on lactating, pregnant, or breeding females
  • Quickly eliminates chewing lice infestations
  • Controls and prevents reinfestation
  • Kills lone star, American dog, brown dog, and deer ticks (the primary carrier of Lyme disease) in every stage
  • Kills fleas, which are associated with flea allergy dermatitis
  • Prevents development of fleas in all life stages (pupae, larvae, and eggs)
  • Kills flea larvae, eggs, and adult fleas
  • Prevents and stops infestations

How does Frontline Plus for Cats and Kittens work?

Frontline Plus for Cats uses S-methoprene, an IGR (insect growth regulator), along with fipronil. These ingredients work in tandem to target fleas in all life stages. Fipronil works by collecting in the hair follicle and skin oils, and it continues to release from the follicles of the hair onto the coat and skin of the cat. This leads to lasting protection against chewing lice, ticks, and fleas.


Boehringer Ingelheim

Active ingredient(s):

Fipronil 9.8%, (S)-Methoprene 11.8%

How is Frontline Plus for Cats and Kittens sold?

Frontline Plus Cats & Kittens is sold over the counter (OTC) in 3,6, and 12 month supply.

What are the side effects of Frontline Plus for Cats and Kittens?

The most common side effect is application site irritation. This is typically temporary. If symptoms continue or worsen within a few days after application, seek immediate veterinary attention.

What special precautions are there?

  • Thoroughly wash hands with soap and water after handling this product.
  • Do not allow contact with clothing, eyes, or skin.
  • Eye injury can occur. If contact occurs, use plenty of water to flush the eyes, and seek medical attention if the irritation does not subside.
  • This flammable product should not be exposed to open flame or heat.
  • Harmful if swallowed by a human. Contact a poison control center or physician for advice. Patient should sip water in the meantime. Never induce vomiting unless the patient is conscious and it has been advised by a medical professional.
  • Only safe for external use on kittens and cats.
  • Safe for use on nursing, pregnant, or breeding animals.
  • Discuss with your veterinarian if your pet is on any medication or pesticide, or if your pet is aged or debilitated.
  • Keep out of reach of children.
  • To dispose wrap original container in several layers of newspaper and discard in trash.

What to do if overdose?

Contact your closest emergency pet hospital.

How can I store Frontline Plus for Cats and Kittens?

Store at room temperature in original container.


To kill fleas, and all stages of brown dog ticks, American dog ticks, lone star ticks, and deer ticks (which may carry Lyme disease) and chewing lice, apply to cats and kittens (8 weeks or older) as follows:

Remove applicator from child-resistant package. Hold applicator upright and snap applicator tip away from face and body. Place applicator tip through animal’s hair to the skin level between the shoulder blades.

Squeeze applicator, applying entire contents in a single spot to the animal’s skin. Avoid superficial application to the animal’s hair. Only one applicator per treatment is needed.
 When used monthly, FRONTLINE® PLUS FOR CATS completely breaks the flea life cycle and controls tick and chewing lice infestations. Research demonstrates that FRONTLINE® PLUS kills adult fleas, flea eggs, and flea larvae for up to six weeks. FRONTLINE® PLUS also prevents development of all flea stages for up to six weeks. FRONTLINE® PLUS kills ticks for at least one month. A once monthly application is recommended where tick control is needed. Although FRONTLINE® PLUS can control fleas for up to six weeks, if there is a high risk of reinfestation or if the pet has fleas which may cause flea allergy dermatitis, a once monthly application may be needed.

FRONTLINE® PLUS FOR CATS remains effective even after bathing, water immersion, or exposure to sunlight. Avoid contact with treated area until dry. Do not reapply FRONTLINE® PLUS for 30 days.

Main Ingredients










How to Combat Flea and Tick Attacks in Winter. Read the article here.

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Frontline Plus for Cats and Kittens

Customer Submitted Questions

What works for fleas, ticks, and intestinal worms

1 Answer

Would Frontline work in a house with multiple cats?

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does this work on cats of all weights

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