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Trifexis Chewable Tablets for Dogs Rx

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Product Description

Trifexis for Dogs is a monthly chewable that kills fleas, prevents heartworm disease, and treats and controls adult hookworm, whipworm and roundworm infections. See the Allivet Heartworm Comparison chart to find which heartworm prevention is best for your pet. 

What is Trifexis Chewable Tablets for Dogs?

Trifexis Chewable Tablets are a monthly chewable pill that protects dogs against fleas and worms. Trifexis treats your dog’s intestinal infections from adult hookworms, roundworms, whipworms, and kills adult fleas.

Who is Trifexis Chewable Tablets for Dogs for?

Trifexis is for dogs and puppies 8 weeks of age or older. Trifexis should not be used on puppies or dogs under 5 lbs.

Why use Trifexis Chewable Tablets for Dogs?

-Trifexis kills fleas before they can lay eggs and begins killing biting fleas within 30 minutes. -Trifexis is a beef-flavored, easy to administer chewable tablet, so you can offer it to your dog as a treat. -Trifexis treats and controls roundworms, hookworms, and whipworms -Trifexis prevents heartworm disease and will kill any immature heartworms your dog was exposed to in the preceding month.

How does Trifexis Chewable Tablets for Dogs work?

Trifexis prevents flea infestations and protects your dog from parasites with one monthly tablet. The main ingredient in Trifexis is spinosad, which prevents and controls flea infestations by killing adult fleas. The primary target of action of spinosad is an activation of nicotinic acetylcholine receptors (nAChRs) in insects. Spinosad, starts to work within 30 minutes to kill fleas and has been proven to kill 100% of all biting fleas within 4 hours. Milbemycin oxime is the other active ingredient in Trifexis and is used to prevent heartworms. Milbemycin oxime kills adult hookworms, roundworms and whipworms. It kills the immature form of the heartworm (Dirofilaria immitis), which is transmitted to dogs by mosquitoes.


Elanco Animal Health

Active ingredient(s):

Spinosad and Milbemycin Oxime

How is Trifexis Chewable Tablets for Dogs sold?

Trifexis is sold in 3, 6, and 12 month packs for dogs ranging from 5 to 120 lbs. Select the appropriate Trifexis product for your dog’s weight: Product Label Color / Dog’s Weight Pink 5 - 10 lbs Orange 10.1 - 20 lbs Green 20.1 - 40 lbs Blue 40.1 - 60 lbs Brown 60.1 - 120 lbs

What are the side effects of Trifexis Chewable Tablets for Dogs?

The most common adverse reactions recorded in clinical trials were vomiting, pruritus, lethargy and diarrhea. If vomiting occurs within an hour of administration, you can give your dog another full dose. Puppies less than 14 weeks of age may experience a higher rate of vomiting.

What special precautions are there?

Your dog should be tested for heartworm infection before starting Trifexis. Trifexis has not been evaluated for safe use in breeding males. Use with caution in dogs with pre-existing epilepsy.

What to do if overdose?

Contact your nearest emergency animal hospital in the event of overdose or adverse reaction while using Trifexis.

How can I store Trifexis Chewable Tablets for Dogs?

Store Trifexis at room temperature (68-77° F)

Helpful Tips:

Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, your dogs should be tested for existing heartworm infection. Use with caution in breeding females. Trifexis is an oral medication and does not require you to isolate your dog from other pets during treatment.

Pharmacists are standing by to offer Pet Parent counseling regarding prescription medication purchased from Allivet before and after dispensing. Pharmacists on duty are available Monday-Friday, 9:30AM - 5:30PM EST and will be on call Saturday 12:00PM - 4:00PM EST for consultation.

Trifexis is a prescribed pet medication for the prevention of fleas and parasites such as roundworm, hookworm and heartworm. Follow your veterinarian's directions on when to give this medication. If you are advised to give it seasonally for heartworm prevention, remember to give it during the mosquito season and 3 months beyond, preferably on the same date each month.

Trifexis should be used as recommended by your veterinarian. If you have difficulty giving the medication to your dog, contact your veterinarian. 
Dosages of Trifexis by Weight for Dogs Over 8 Weeks of Age

Weight                  /                       Dosage
5-10 lbs                             1 Tab (Pink Label box)
10.1 - 20 lbs                    1 Tab (Orange Label box)
20.1 - 40 lbs                     1 Tab (Green Label box)
40.1 - 60 lbs                     1 Tab (Blue Label box)
60.1 - 120 lbs                  1 Tab (Brown Label box)
Over 120 lbs                    Vet’s Prescribed Dosage

If you do not administer Trifexis monthly throughout the year, the final dose must be given no fewer than three months following the last exposure to mosquitoes. Please speak with your vet for any question regarding Trifexis dosage or missed dosages. 

Trifexis is manufactured by Elanco Animal Health and contains the following active ingredients:

Active Ingredients           /             Amount per Tablet
Spinosad                                                140 mg
Milbemycin Oxime                                2.3 mg

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Trifexis Chewable Tablets for Dogs

1 Questions 0 Answers

Can you answer these questions?

We have a large and a small dog. Can I just order the packet for large dogs and divide one tablet into 3 pieces/doses for my smaller dog? Large dog is 90 lbs and small dog is 17 lbs.

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