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Advantage II for Cats

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Product Overview

How To Use

What’s in it?


Questions & Answers

Product Description

Advantage II eradicates and protects your cat from fleas no matter what stage of their lifecycle they are in. This once a month medication is excellent for stopping infected pets from coming into the home. See Allivet's Flea and Tick chart to find which flea and tick product is best for your pet.

Who is Advantage II for Cats for?

This product is indicated for use in cats and ferrets. Do not use in kitten 8 weeks of age and younger.

Why use Advantage II for Cats?

This product holds a range of anti-flea benefits:
  • Exterminates fleas at all stages of life cycle.
  • Inhibits biting in 3 to 5 minutes
  • Manages existing infestations
  • Stops potential for future infestations
  • Exterminates fleas within 12 hours of first administration
  • Exterminates reinfesting fleas within 2 hours
  • Initiates effect upon contact (fleas aren’t required to ingest product to be exterminated) Waterproof

How does Advantage II for Cats work?

This product’s mechanism of action works via imidacloprid and pyriproxyfen, ingredients that are able to exterminate infesting fleas upon contact—which works to cut out the need for fleas to bite in order to be exterminated. A single administration of this product can be effective for up to a month.


Bayer Animal Health

Active ingredient(s):

9.1% Imidacloprid
0.46% Pyripoxyfen

How is Advantage II for Cats sold?

Available in 4, 6, or 12 month supply based on weight.
  • Orange: Cats between 5-9 lbs
  • Purple: Cats over 9 lbs

What are the side effects of Advantage II for Cats?

This product may lead to lack of energy and increased durations of sleep. Fluctuations in behavior, such as irritation, unrestrained grooming, concealing oneself from social spaces, irregular pacing, thirst, and coughing, may occur. Uncomfortable sensations at the administration area may lead to behaviors like rubbing or itching. Heightened salivation may occur during the first hour of use. In the situation that cat licks the area of administration, the likelihood of salivation, tremors, vomiting, and lack of hunger will rise.

What special precautions are there?

Not to be used in kitten less than eight weeks old. Be sure to ask your veterinarian before administering to weak, old, pregnant, nursing cats. Reactions resulting from sensitivity to pesticides may come about. If symptoms linger, worsen, or become severe, be sure to contact your veterinarian at once. In the case of pets already taking other medicines, talk to your veterinarian before administering this product.

What to do if overdose?

Contact your closest emergency pet hospital.

How can I store Advantage II for Cats?

Store in a dry and cool environment.

Helpful Tips:

This product holds the following benefits:
  • Works after initial application
  • Works after contact with rain or sun
  • Month to month applications result in effective management and inhibition of reinfestation


Directions :
Part the hair at the base of the cat’s head, place the tip of the tube on the exposed skin and squeeze twice to apply. Lift the tube away from the skin and then release the pressure. Keep the product away from the cat’s eyes; do not allow the cat to lick the product or ingest it in any way. If you have multiple pets, keep the pets separated from each other to prevent them from licking each other’s application sites.
How to Open :
1. Being careful not to cut close to the blister cavities, take scissors and cut off one section of the card containing a single tube.
2. Take the separated section, and cut into the blister cavity across the small side, close to the cap of the tube.
3. Peel off the foil, and take out the tube.
4. Repeat steps 1 to 3 for each tube.
How to Apply :
1. Use only on cats and kittens. Do not use on other animals.
2. Remove one applicator tube from the package. See “HOW TO OPEN” section
3. Hold applicator tube in an upright position. Pull cap off tube.
4. Turn the cap around and place other end of cap back on tube.
5. Twist cap to break seal, then remove cap from tube.
6. Part the hair on the neck at the base of the skull until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents of the tube directly on the skin. Do not get this product in your cat’s eyes or mouth. The product is bitter tasting and salivation may occur for a short time if the cat licks the product immediately after treatment. Treatment at the base of the skull will minimize the opportunity for the cat to lick the product.
7. Discard empty tube as described in Storage and Disposal.
8. Under normal conditions the product is effective for a month. However, in cases of severe flea infestation, retreatment may be necessary earlier than four weeks.
Do not retreat more often than once every fourteen (14) days for kittens or once every seven (7) days for small and large cats. After flea control is attained, return to a monthly retreatment schedule.

Main Ingredients

Active ingredients: Imidacloprid 9.10%, Pyriproxyfen 0.46%. Other ingredients: 90.44%.

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Advantage II for Cats

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