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Adequan Canine 100mg/ml 5 ml Vial

By Adequan
(373 reviews)
Veterinary Diet Item
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Adequan Canine 100mg/ml 5 ml Vial

By Adequan
Mfg. Price $174.98
One-time purchase
$174.98 Save Up to 50% on Your First AutoShip
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Count: 100 mg/ml 2 x 5 ml Vials (2 Pack)
Count: 100 mg/ml 2 x 5 ml Vials (2 Pack)
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Product Overview

Adequan Canine is an injectable drug approved by the FDA to control symptoms caused by non-infectious traumatic or degenerative arthritis in the synovial joints or after joint surgery.
For use in dogs with joint pain, inflammation, and other canine arthritis-related symptoms.
Adequan is ideal for quickly improving joint mobility after surgery. It can also aid in controlling signs of traumatic joint arthritis and degenerative joint diseases.
Adequan Canine works to reduce joint inflammation, increase joint fluid (synovial fluid) thickness, enhance cartilage production, and aid in the production of healthy synovial fluid.
Studies have shown the following self-limiting and mild reactions in a low number of dogs:
  • Transient injection site pain
  • Temporary diarrhea
  • Abnormal bleeding
These reactions were determined to require no therapy interruption.
Polysulfated Glycosaminoglycan
Contact your closest emergency pet hospital.
  • Administer with caution to dogs with hepatic or renal impairment.
  • Never administer to a dog with a suspected or known bleeding disorder.
  • Never administer to dogs with PSGAG (synthetic steroid) hypersensitivity.
100 mg/ml 5 ml vial sold in single or double pack.
American Regent, Inc.
Following several doses, the effects of this medication will be shown through increased playfulness and an increase in activity levels.
The recommended dose of Adequan® Canine is 2 mg/lb body weight (.02 mL/lb, or 1 mL per 50 lb) by intramuscular injection only, twice weekly for up to 4 weeks (maximum of 8 injections). Do not exceed the recommended dose or therapeutic regimen.

Do not mix Adequan® Canine with other drugs or solvents.
Adequan contains 100 mg of polysulfated glycosaminoglycan and 0.9% v/v benzyl alcohol (a preservative). Other ingredients include water, sodium hydroxide, and/or hydrochloric acid added when necessary to adjust pH. Sodium chloride may also be added to adjust tonicity.

About This Product

Customer Reviews

4.9
373 reviews
5 339
4 30
3 4
2 0
1 0
Customer review photo
Martha B Verified Purchase
October 4, 2026

Works really well for arthritis

Mary B Verified Purchase
August 4, 2026

Works for my lab is left hip is bad, not limping anymore

Julie S Verified Purchase
July 31, 2026

Adequan has really helped my 14yo Golden

My Golden Retriever has been on adequan for arthritis in her back for several years now. She’s never had any side effects. She’s also 14 years old and still going strong—joint pain does not limit her activity. Putting her on adequan and keeping her on it has been a great decision.

William t Verified Purchase
October 8, 2025

Buddy

So far we are on inject # 4. I know anything I’ve read staes he should not be having the effect of Adequan yet but his limping is much better and some of the time not at all. Buddy may be 16 years old and living his best life here in north Florida with us. He was between 2 and 3 years old when he was found in southern Georgia on the road side in the forest area. We fostered him in 2012 and failed. I know he won’t be are much longer, but hopefully will so we want the best for him and Aequan so far is a game changer for Buddy!

Elaine E Verified Purchase
November 9, 2024

Our girl has hip dysplasia. Adequan has helped her when she is very active. She is moving around better with no limp and is more playful with the other pups.

Elaine E Verified Purchase
September 15, 2024

Our 8yo has hip dysplasia. We began injections to slow down the progress. Altho she is already very active, we have noticed she is doing things and moving in ways she hasn't in many years. It has definitely helped her.

Melissa C
September 7, 2024

I've been using the Adequan for my 11yr old Great Dane and it has proven to be affective in helping with her OA. It definitely helps keep her comfortable and moving. Definitely recommend if you're open to learning how to give the injection or are experienced.

David M
February 2, 2024

My nearly 13 yr old bull terrier Rae is still climbing the stairs although reluctantly now at her age. We've been using Adequan for around 4 yrs now. She still has many more good days than bad ones!

Jeanine D Verified Purchase
December 5, 2023

This gave my senior dog with arthritis and spondylosis his activite lifestyle back. From too painful to move to walking, playing and jumping again. We've seen a huge improvement in his quality of life with continued use.

Clare S Verified Purchase
November 6, 2023

My Cat has severe Arthritis. Doctor recommended injections of a much smaller dose of the dog version for pain relief.

Rebecca M Verified Purchase
November 2, 2023

My dog has bone dysplasia in his elbows, this medicine helps so much

Heather M Verified Purchase
September 7, 2023

Adequan has made a big difference in the mobility of my 5 yr old Rottweiler. She went from limping to running around like a pup!

Margaret S Verified Purchase
September 5, 2023

Blue Heeler Sydney will be 14 y.o. Sept. 29th! He is a retired Agility CH. and loving life and pushing his herding ball around for fun. Monthly shot of Adequan and his daily Antinol help keep him movin' and a groovin'!

Eric B Verified Purchase
August 22, 2023

I have a 12 year old Labrador mix with severe osteoarthritis. We have managed her condition with anti-inflammatory meds and pain management med. She was prescribed Adequan about three weeks ago and is beginning to show greatly improved mobility. Her prior limping is less noticeable she has become more playful. If she continues to improve, Adequan will be a blessing to her quality of life.

KAREN J Verified Purchase
June 24, 2023

This medication has given my dog good range of motion and relieved his arthritis discomfort.

Janet S Verified Purchase
May 29, 2023

I have a dog with arthritis in his back. Vet recommended this product and it works

Barbara Z Verified Purchase
May 17, 2023

Works well for my dog. He is walking much better. We know when it is time for his injection.

Carol W Verified Purchase
April 17, 2023

Helps keep my 9 year old moving like a puppy

Celena M Verified Purchase
February 6, 2023

This is a miracle medication. I wish more people knew if it. I wish more veterinarians would be writing Rx's for Adequan instead of things like Rimadyl.

Beth H
January 10, 2023

We have had our little blonde cocker Daisy on this for a year. She is feeling so much better, more agile, more energetic, and less stiff when she wakes in the am, after naps, and after her walks. It is also very easy to administer.

Stephanie F Verified Purchase
December 3, 2022

This medication changed our dog's life! He went from hobbling around after 2 knee surgeries to running around like he was 5 again at 11 yrs old. It was an absolute miracle 🙏

Carlotta B Verified Purchase
November 29, 2022

Best price anywhere. Staff are always great! Get lots of meds from here and they're always quick and accurate.

Louise C Verified Purchase
November 13, 2022

truly helps relieve arthritic condition

Bill E
November 2, 2022

Our little girl is doing so much better now. The auto ship means one less thing for us to worry about.

Michael P
October 13, 2022

Helps with my little buddy's arthritis.

Teresa B Verified Purchase
September 25, 2022

An added backup for pain.meds

Carola T Verified Purchase
March 28, 2022

Our little dog with leg joint problems was in pain and barely able to walk. Often, her leg kept collapsing and she would not eat the joint supplements we initially tried. I was so glad to see her walk again and being in better spirits without the pain in her hind legs after she is on the Adequan injections. Adequan really made a big difference!

Margarita M Verified Purchase
March 24, 2022

This is such a godsend for our kitty. He's a 15 year old with OA. You see the difference when he goes too long without Adequan. This stuff gives him more freedom and be gets around better and faster now than before being placed on Adequan. This is the reason we now stick to a a monthly shipment, so he never goes without.

Maryellen M Verified Purchase
March 17, 2022

Adequan makes a huge difference for my elderly Rottie, and it can be given SUBQ if you're not familiar with giving it IM.

Christina F Verified Purchase
February 17, 2022

Adequan (along with supplements, exercise & regular chiropractic care) has allowed my 16.5yr old husky to still enjoy life! Her arthritis is manageable even at this age; we go for daily walks and she continues to impress everyone she meets.

Robert D Verified Purchase
January 25, 2022

This medicine works great.

Willam B Verified Purchase
January 11, 2022

Allivet, my favorite pet pharmacy

Nicolle K Verified Purchase
December 14, 2021

To help my Lumi walk around a little bit more easily

Sigberto C Verified Purchase
September 23, 2021

Dr. Gordon perscribed this med for our pet

Sabrina G Verified Purchase
August 30, 2021

My senior kitty has arthritis and I thought I was going to have to put him down. He was refusing to get up and walk around at all. We started adequan injections under the skin and within a week or two was back to his normal self. We are on it weekly and I have learned how to give his injections at home. This is amazing and and I highly recommend it.

Patricia L Verified Purchase
August 30, 2021

We've been using this for our 10 yr old tripaw for some time. He has much arthritis and displays significant relief when he's had a shot. Over time we have been able to reduce his dose because he's be able to exercise more with less pain.

Sabrina G Verified Purchase
August 30, 2021

My senior kitty has arthritis and I thought I was going to have to put him down. He was refusing to get up and walk around at all. We started adequan injections under the skin and within a week or two was back to his normal self. We are on it weekly and I have learned how to give his injections at home. This is amazing and and I highly recommend it.

Patricia L Verified Purchase
August 30, 2021

We've been using this for our 10 yr old tripaw for some time. He has much arthritis and displays significant relief when he's had a shot. Over time we have been able to reduce his dose because he's be able to exercise more with less pain.

Ellen M Verified Purchase
August 23, 2021

Amazing improvements with joint pain and mobility!

Ellen M Verified Purchase
August 23, 2021

Amazing improvements with joint pain and mobility!

Arvin V Verified Purchase
August 18, 2021

effective to our dog

Arvin V Verified Purchase
August 18, 2021

effective to our dog

Mancil L Verified Purchase
August 13, 2021

It really works for my dog.

Mancil L Verified Purchase
August 13, 2021

It really works for my dog.

Linda J Verified Purchase
August 12, 2021

Good price

Diana P Verified Purchase
August 12, 2021

Its been helping my dog for over a year!!

Linda J Verified Purchase
August 12, 2021

Good price

Diana P Verified Purchase
August 12, 2021

Its been helping my dog for over a year!!

OShara C Verified Purchase
August 2, 2021

Adequan has improved our dogs quality of life.

Thomas G Verified Purchase
July 29, 2021

Fast, convenient delivery and savings on veterinary prescriptions!

Kurumi H Verified Purchase
July 29, 2021

I have been giving to my old sweet lady. She is walking slow but keep going 👍

Yolanda V Verified Purchase
July 29, 2021

Very reasonable price.

Robert D Verified Purchase
July 13, 2021

I give my cat a shot of this every week to help with her arthritis. It works well

J G Verified Purchase
July 8, 2021

My 14 year old cat was starting to have some mobility issues. The base of her tail was getting very oily and I was helping her keep it clean. A month or 2 into giving her Adequan injections, she was able to keep up with her own grooming again, and started playing more vigorously!

Mary B Verified Purchase
July 8, 2021

Service has been good, just wish I was told I could lock in the price on the first order.

Kimberly H Verified Purchase
June 29, 2021

Cheaper than vet

JAVIER L Verified Purchase
June 14, 2021

I bought it because I have read reviews on the medication and what it does my 13yr is having trouble with arthritis and dysplasia.. Hopefully it will help.

Rosemary M Verified Purchase
June 14, 2021

Medicine helps our dog’s arthritis.

Marie F Verified Purchase
May 20, 2021

Service is excellent and the meds are working

Katee R Verified Purchase
May 10, 2021

My vet recommended Adequan for my now 12yr old German Shepherd with Degenerative Myelopathy. This works wonders in addition to the other arthritis and pain medications he is on. We've been able to slow the progression and keep him happy and moving. He seems less stiff and he's able to get up (slowly of course) onto the couch again. He even has bouts of energy were he runs and plays with the other dogs outside in the yard. I'm so happy we are able to keep our best friend comfortable in his golden years.

Andree H Verified Purchase
May 5, 2021

Very cheap

Michelle R Verified Purchase
May 3, 2021

Easy ordering and speedy delivery.

Katherine G Verified Purchase
May 3, 2021

Love this service! Not only well priced but so easy

Linda H Verified Purchase
May 3, 2021

Bella had surgery and her doctor recommend this product to prevent arthritis. Bella will need to take this for the rest of her life and we are blessed.

Jean W Verified Purchase
May 3, 2021

It helps my cats arthritis!

DANIEL W Verified Purchase
May 3, 2021

Has been very helpful for our dog's mobility and reduction of associated pain.

K L Verified Purchase
May 3, 2021

Adequan really helps my 14 year old dog move better

Melissa F Verified Purchase
May 3, 2021

Charlie, my 11 year old yellow lab has arthritis and has a hard time sitting, getting up, and walking. I was using a different product that was cheaper for a while (ICHON)but since switching to Adequan, I've noticed a huge difference in my fur kids mobility. I wish I had been using this all along!!!

Frances K Verified Purchase
May 3, 2021

Excellent Product. Product provides almost immediate results,

Dion S Verified Purchase
May 3, 2021

Arthritis for senior dogs

Roshella J Verified Purchase
May 3, 2021

This has been a lifesaver for my dog and this is much cheaper than I can get it from my vet

Patricia L Verified Purchase
May 3, 2021

Adequan helps Buster move and relieves his arthritis pain.

Meagan C Verified Purchase
May 3, 2021

Works fabulously

Sharon T Verified Purchase
May 3, 2021

helps my dog

Mika F Verified Purchase
May 3, 2021

My dog moves better after this injection.

Diane W Verified Purchase
May 3, 2021

Easy to order!

Karen S Verified Purchase
May 3, 2021

Helps with arthritis pain management.

Danelle M Verified Purchase
May 3, 2021

I have used this for both of my Shepherds a decade apart. I still find it helpful during the Golden Years. I suggest starting it sooner rather than later. At Gracies stage it will only help her not keep loosing and/or help her comfort level increase. If you start early enough it will help build cartilage thus reversing the process of deterioration. I was able to administer it myself sub-Q.

Patricia K Verified Purchase
May 3, 2021

Best pricing

Deborah l Verified Purchase
April 28, 2021

great prices, way better than the vet's pharm. Actually the vet recommended them to.

Judith L Verified Purchase
April 26, 2021

This product is helping my 7year old sheltie that has spondylosis ,I am using this medicine with other treatments and it seems to be working well . Thank you Allivet

Tina D Verified Purchase
April 26, 2021

I bought Adequan at my vets advice for treating my Border Collie's hip and joint issues. Allivet was the least expensive in comparison to other online canine medication companies and even compared to my vet. Ordering has been easy and efficient.

Marianne S Verified Purchase
April 26, 2021

Allivet has wonderful and efficient customer service staff. I have been using them over a year.

JAMES C Verified Purchase
April 26, 2021

good service

Julie c Verified Purchase
April 26, 2021

good price and works well

Phyllis G Verified Purchase
April 26, 2021

I cannot say enough good about this product. It does not have to break down in the body like the tablets and goes right to work. If you don't have a problem with needles, this is your go to for your arthritic pet. My girl also tore ACL and too high risk for surgery. This along with therapy is a great help!

Mark S Verified Purchase
April 26, 2021

Great service

Robert D Verified Purchase
April 26, 2021

Its been working great with all my cats.

Martha S Verified Purchase
April 26, 2021

Great price!

Jackie S Verified Purchase
April 26, 2021

Love it works great

Mark S Verified Purchase
April 26, 2021

Great service. The expiration date always gives us plenty of time to use.

YVONNE D Verified Purchase
April 26, 2021

This is my first time buying meds on line and it was quite comfortable

Robert B Verified Purchase
April 26, 2021

Giving Adequan injections Sub-Q as recommended by my Vet. Has worked wonders for my 12 yr old Labrador with DJD and possible CCL tear. His mobility has dramatically improved. He just had his 8th injection with the initial 4 week period. Have discontinued Novox and Gabapentin for now because not needed!

Toni L Verified Purchase
April 26, 2021

Allivet was recommended to me by my vet. My dog has to be on Adequan indefinitely and told me where to order. Allivet makes it very easy to find what you need and once you fill in your info they do the rest. Very impressed. When I order it’s usually arrives in 3-4 days. Thank You Allivet.

Deborah W Verified Purchase
February 16, 2021

My two German Shepherds would be a mess without this.

Teresa B Verified Purchase
February 1, 2021

Helps with acl problems

Janelle b Verified Purchase
January 28, 2021

I have almost every animal at my house on this. What a difference and so easy!

Robert R Verified Purchase
January 20, 2021

Exactly as promised. Arrived quickly.

Daniel M Verified Purchase
December 8, 2020

I have been using this on my 13 year old and it has really helped him with his limp and old age. Walking better and tackling the stairs again. Super easy to administer shots.

Kim N Verified Purchase
November 23, 2020

Comes highly recommended by my vet & definitely helped ease my big girls’ pain

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