Can I use Frontline if dog is on Simpirca trio?

Frontline Plus and Simparica Trio both provide flea and tick protection. Please consult your veterinarian before using these products together to ensure the combination is safe and appropriate for your dog.

Do I need a prescription to purchase Frontline

Frontline Plus is an over the counter product. It does not require a prescription.

What is the return policy

Allivet’s Customer Friendly Return Policy: Shop from home with ease and the comfort of knowing that Allivet offers a 100% Satisfaction Guarantee on all over the counter medications. Our 30-Day Guarantee allows you the time needed to check items for accuracy; color, quantity, and size for your pet, etc. In the highly unlikely event you are not completely satisfied with your purchase from Allivet (with the exception of prescription drugs and vaccines), we will gladly accept your return for an exchange or a refund. Kindly return your unused, unopened items in their original box and/or packaging in new condition within 30 days for a replacement or refund. Please note that shipping charges on returned items are non-refundable. Please contact our Customer Care Specialists at 1-877-500-9944 for further assistance on our return process. When returning an item, please contact our Customer Care Specialists at 1-877-500-9944 to obtain a return authorization, then, please ship your return package to the following address: Allivet - Returns 14540 NW 60th Avenue Miami Lakes, FL 33014

I have a 3.4 lb. chihuahua. How much frontline can I give her?

Frontline is not recommended for pets under 5 lbs. Please consult with your veterinarian for their recommendations for your pet.

Order Type	Subtotal¹	Shipping
Rx AutoShip²	Over $30	FREE!
Rx or OTC³	Over $49	FREE!
Rx or OTC	Under $49	$6.95 Flat Rate

hero banner

hero banner mobile

Frontline Plus For Dogs

Name: Frontline Plus for Dogs | Flea & Tick Spon-On
Brand: Frontline
SKU: 26834-2
Price: 149.96 USD
Availability: InStock

(375 reviews)

Have an account?

Frontline Plus for Dogs 23 - 44 lbs 12 Month Supply Blue

Click on image to open expanded view Item No. 26834-2

Frontline Plus For Dogs

Have an account?

Weight and Color: 23-44 lbs Blue

Month Supply: 12 Month Supply

Weight and Color: 23-44 lbs Blue

Month Supply: 12 Month Supply

Best Price Guarantee Found a lower price? We'll beat it

Buy Once $149.96
AutoShip & Save
AutoShip $124.96

Save 5% on Future Shipments
Free Shipping Over $30
Change, Skip, or Cancel Anytime

Quantity

This Item Ships FREE!

Special Discount Applied!

California Residents: Prop. 65 Warning

This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

Product Overview

Keep your dog protected with the #1 name in flea & tick protection*, FRONTLINE®. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years**— FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINEPlus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations and keep your pets protected year-round.

References:

*Data on file at Boehringer Ingelheim.

**Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.

FRONTLINE Plus for Dogs is a monthly topical that effectively controls fleas, ticks, and lice.

For use only on dogs/puppies over 8 weeks of age with four different sizes available for dogs weighing between 5-22 lbs., 23-44 lbs., 45-88lbs., and 89-132 lbs.

The #1 name in flea and tick protection*
Trusted by pet owners for over 20 years**
Fast-acting, long-lasting & waterproof flea and tick treatment
Protects from fleas and ticks for a full month
Kills adult fleas, flea eggs, flea larvae, ticks, and chewing lice
Aids in the control of sarcoptic mange infestations
Stops existing flea infestations and prevents establishment of new infestations
For dogs eight weeks or older, in four sizes based on dog’s weight (This product is approved for use on dogs XX-XX pounds).

References:

*Data on file at Boehringer Ingelheim.

**Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.

FRONTLINE® Plus for Dogs contains fipronil and the insect growth regulator (IGR) (S)-methoprene. Fipronil kills fleas by affecting their nervous system, making them hyperactive before dying. These dying fleas often rise to the top of the dog’s hair coat as they are dying. The (S)-methoprene prevents all flea stages (eggs, larvae, pupae) from developing.

Dogs may experience some temporary irritation at the site of application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

fipronil, (S)-methoprene

Contact your vet or nearest animal hospital.

For external use only. Do not use on puppies under 8 weeks of age and less than 5 lbs. Individual sensitivities, while rare, may occur after using any pesticide product.

FRONTLINE® PLUS FOR DOGS is available Over the Counter (OTC) in 3, 6, and 12 month supplies.
Boxes are color coordinated according to your dog's weight.

Orange: 5 - 22 lbs. (Small Dogs)
Blue: 23 -44 lbs. (Medium Dogs)
Purple: 45-88 lbs. (Large Dogs)
Red: 89 - 132 lbs. (Extra Large Dogs)

Boehringer Ingelheim

Apply entire contents of container to one spot. Do not apply on the hair. Apply directly to skin.

READ ENTIRE LABEL BEFORE EACH USE. To apply, simply follow these instructions and repeat every 30 days: Use scissors to separate one FRONTLINE® Plus for Dogs blister and cut along dotted line to peel down foil to remove the applicator. Open the applicator by holding upright with foil side toward you and snap applicator tip. Next, part your dog's hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the dog's skin. Do not apply on top of the haircoat. Avoid contact with treated area until dry. Do not allow your dog to ingest this product. [Do not apply to dogs weighing less than [5 lbs.] [23 lbs.] [45 lbs.] [89 lbs.] or younger than 8 weeks of age.][Do not use two applicators for dogs weighing more than 132 lbs.] Do not use more than one application per dog per month.

FOR DOGS & PUPPIES 8 weeks or older

Convenient spot treatment for fast-acting, long-lasting control of fleas, ticks and chewing lice.

Active ingredients: fipronil and (S)-methoprene

INERT INGREDIENTS 81.4%

TOTAL 100.0%

About This Product

Frontline Plus For Dogs Description

References:

*Data on file at Boehringer Ingelheim.

**Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.

What is Frontline Plus For Dogs?

FRONTLINE Plus for Dogs is a monthly topical that effectively controls fleas, ticks, and lice.

Which animals/pets is Frontline Plus For Dogs for?

For use only on dogs/puppies over 8 weeks of age with four different sizes available for dogs weighing between 5-22 lbs., 23-44 lbs., 45-88lbs., and 89-132 lbs.

Frontline Plus For Dogs uses

The #1 name in flea and tick protection*
Trusted by pet owners for over 20 years**
Fast-acting, long-lasting & waterproof flea and tick treatment
Protects from fleas and ticks for a full month
Kills adult fleas, flea eggs, flea larvae, ticks, and chewing lice
Aids in the control of sarcoptic mange infestations
Stops existing flea infestations and prevents establishment of new infestations
For dogs eight weeks or older, in four sizes based on dog’s weight (This product is approved for use on dogs XX-XX pounds).

References:

*Data on file at Boehringer Ingelheim.

**Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.

What does Frontline Plus For Dogs do?

Frontline Plus For Dogs side effects

Dogs may experience some temporary irritation at the site of application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

Frontline Plus For Dogs ingredients

fipronil, (S)-methoprene

Frontline Plus For Dogs overdose: What to do?

Contact your vet or nearest animal hospital.

What to know before using Frontline Plus For Dogs

For external use only. Do not use on puppies under 8 weeks of age and less than 5 lbs. Individual sensitivities, while rare, may occur after using any pesticide product.

How is Frontline Plus For Dogs sold?

FRONTLINE® PLUS FOR DOGS is available Over the Counter (OTC) in 3, 6, and 12 month supplies.
Boxes are color coordinated according to your dog's weight.

Orange: 5 - 22 lbs. (Small Dogs)
Blue: 23 -44 lbs. (Medium Dogs)
Purple: 45-88 lbs. (Large Dogs)
Red: 89 - 132 lbs. (Extra Large Dogs)

Manufacturer

Boehringer Ingelheim

Tips for using Frontline Plus For Dogs

Apply entire contents of container to one spot. Do not apply on the hair. Apply directly to skin.

Overview

Main Ingredients

FOR DOGS & PUPPIES 8 weeks or older

Convenient spot treatment for fast-acting, long-lasting control of fleas, ticks and chewing lice.

Active ingredients: fipronil and (S)-methoprene

INERT INGREDIENTS 81.4%

TOTAL 100.0%

Customer Reviews

4.8

375 reviews

5 349

4 15

3 8

2 4

1 0

Lisa H Verified Purchase

August 13, 2026

Good quality, great price

The Frintline Plus is a great product. It works well. And Allivet's price was really good. I compared bef buying.

Donna K Verified Purchase

August 10, 2026

Easy to use product!

Simparica Trio ^Rx

Nexgard ^Rx

Credelio Quattro CA1

NexGard Combo ^Rx

Revolution Plus ^Rx

Apoquel Tablet ^Rx

ToDAY ^Rx

ToMORROW ^Rx

AutoShip

How to Order Your Prescription?

Allivet AutoShip

NexGard® Plus

Simparica Trio ^Rx

Nexgard ^Rx

Credelio Quattro CA1

NexGard Combo ^Rx

Revolution Plus ^Rx

Apoquel Tablet ^Rx

ToDAY ^Rx

ToMORROW ^Rx

AutoShip

How to Order Your Prescription?

Allivet AutoShip

Frontline Plus For Dogs

Best Price Guarantee