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Incurin (Estriol) 1 mg, 30 Tablets

(279 reviews)
Veterinary Diet Item
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Incurin (Estriol) 1 mg, 30 Tablets

$26.99
One-time purchase
$26.99 AutoShip
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Product Overview

Incurin is used to treat spayed female dogs for urinary incontinence. Short-acting estrogen is used to counteract the loss of estrogen in dogs suffering from urinary problems. This markedly reduces, sometimes even eliminates, leakage and accidents caused by urinary incontinence.
Incurin treats urinary incontinence in spayed female dogs with short acting estrogen that counteracts the loss suffered by dogs with urinary issues. This significantly reduces and most times eliminates the leakage and accidents resulting from urinary incontinence. The goal is to give the minimum dose that controls your dog’s symptoms. If the initial dose is working after this time period, try to reduce the dose to ½ tablet per day, then ½ tablet on alternate days.
For use in spayed female dogs.
Features of Incurin:
  • Effective
  • Safe
  • Once-daily, convenient dosing
  • Alternative to Proin and other phenylpropanolamine drugs
  • Restores urinary incontinence in older females and other spayed dogs
Incurin® is activated by short-acting estrogen. It restores the tone of the sphincter muscle when the decreased sphincter control is due to decreased reproductive hormones.
The most frequently reported adverse reactions were:
  • Vomiting (experienced in about 10% of dogs)
  • Appetite reduction (experienced in about 13% of dogs)
Usually, a reduction in dosage controls these effects.
Each tablet contains 1 mg of estriol
In case of overdose, immediately contact the closest pet hospital.
  • Keep away from children.
  • Not safe for human consumption.
  • For animal use only.
  • Some types of estrogen have been linked with changes in bone marrow and an increase in mammary tumor risk. However, post-market pharmacovigilance data and target animal safety study outcomes show that dogs treated with estriol are at lower risk for development of these conditions.
30 single-scored tablets per blister pack.
Merck Animal Health
Incurin® is typically an alternative medication used for incontinence when phenylpropanolamine (Proin, PPA) is no longer effective. However, it may be the first therapy choice due to its effectiveness.
The dose of Incurin® Tablets is not dependent upon body weight. All dogs should receive an initial dose of 2 mg INCURIN™ Tablets (2 tablets) orally once per day for a minimum of 14 days. After urinary incontinence is controlled, the lowest effective daily dose of INCURIN Tablets should be determined by decreasing the dose in a step-wise manner from 2 mg once daily (2 tablets) to 1 mg once daily (1 tablet), then 0.5 mg once daily (1/2 tablet) depending upon the response of the individual dog. There should be a minimum of 7 days between each dose adjustment. After the lowest daily dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days. Dogs should not receive more than 2 mg INCURIN Tablets per day (2 tablets). If the dog does not respond to 2 mg of INCURIN Tablets per day, the diagnosis should be re-assessed.
Incurin contains 1 mg of estriol in each tablet

About This Product

Customer Reviews

4.8
279 reviews
5 257
4 20
3 3
2 0
1 0
Doris M Verified Purchase
October 20, 2026

No more leaks

Incurin works amazing. Pretty much within 24 hours of the first dose you will see the eesukts

Helen K Verified Purchase
October 5, 2026

Incurin tablets

Was easy to place my order.

Doris
September 14, 2026

Excellent response to treatment almost immediately. The only noticeable side effect’s so far are her noticeably enlarged vulva (aka her Lady Parts).

Marilyn w Verified Purchase
September 12, 2026

Life changing product

Making this short and to the point: We do not know what we'd do without this product. Our dog, Sassy, life is 100% due to Incurin.

Anonymous Verified Purchase
June 12, 2025

Incurin affordable and effective

My dog has suffered slight incontinence (leaking) since she was 1 yr old. It is sporadic. I give her 1 tablet a week when needed as per vet's advice. Not 1 tablet a day. She can go months without issue then it starts up again. Definitely cost affective and it works.

Carol F
August 16, 2024

My 13 year old Shepherd's incontinence has been under control since she's been taking one pill a day. Auto ship rids me of worry of ever running out of her prescription.

Pati M Verified Purchase
August 8, 2024

When my collie was spayed at 7 she became incontinent- it took a month to be good - now she will only have an accident maybe twice in last 6 months and only if it is raining. We started with 1/2 tablet daily for couple weeks - not enough? Moved to tablet a day and did the trick. I did as advised by vet, try to go back to 1/2- she needs the whole tablet. This has made my life so much easier - she is in the house and was having an accident every night -

Mark F Verified Purchase
February 4, 2024

This medication works great for my 15yo Terrier mix, who has been incontinent since being spayed at an early age. I wish I was told about it or found it much earlier in her life. The incontinence has stopped almost completely and she is doing great with this medication.

SUSAN G Verified Purchase
October 18, 2023

This helps my Lucy to prevent dribbling urine. She is very self-conscious about being wet. She goes outside and comes running in to lick her wetness on a mat so she doesn't leak.

Sharon C Verified Purchase
April 17, 2023

Helps with incontinence for my dog.

Pia A Verified Purchase
April 5, 2023

I have a spayed 6 year old Airedale Terrier that “leaks” occasionally and it is a surprise to her that it happens. I have had her on incurin for 10 days and I have not noticed any accidents in over a week.

Dr. J Verified Purchase
February 28, 2023

Excellent product and works great on my spayed female. Thanks, Dr. Kreller

LC
November 16, 2022

Allivet has super fast service and sends timely reminders so we never run out!

Wendy W
October 19, 2022

No hassle ordering and delivery is prompt. Communication with my vet is quick!

Eric P Verified Purchase
July 17, 2022

Recommended for my 2 year old spayed Doberman because she continued having accidents in the house 4-5 times a week. 1 tablet each night finally stopped her.

Sharon S Verified Purchase
January 11, 2022

Great convenience in ordering and mailing to my address

Allison M Verified Purchase
November 15, 2021

It was harder to ween her down to 1 pill a day, but it’s working. Crossing my fingers we stay accident free.

Amy F Verified Purchase
November 11, 2021

Cheaper than buying from vet office.

Mona A Verified Purchase
October 7, 2021

My 13 year old Soft Coated Wheaten Terrier is a fixed female. At her age it is not unusual for her to start "leaking". We tried Proin but it didn't help much. Doctor switched her to Incurin and we are dry once again. Minor side effects and I am very happy with the results. Allivet provides excellent customer service and with my move, they worked with me and my new vet to get the meds I need!

Michelle M Verified Purchase
September 23, 2021

Allivet provides the same meds as my vet but in the exact dose and at a fraction of the cost.

Traci M Verified Purchase
September 2, 2021

no more leaking pee. we use this along with Proin ER

DAVID H Verified Purchase
July 16, 2021

Works great for incontinence

SHARON W Verified Purchase
July 8, 2021

Price is better than other available options. Fast Shipping and great customer service.

SUSAN G Verified Purchase
June 7, 2021

Old ornery deaf faithful much loved dog.

Travis C Verified Purchase
May 3, 2021

Because their pricing is half of what my Vet Hospital charges for the exact same thing.

Carol C Verified Purchase
May 3, 2021

Efficient and easy to reorder

Judy W Verified Purchase
May 3, 2021

Love being able to get most my meds here.

William B Verified Purchase
May 3, 2021

quality product shipped on time

Dustin n Verified Purchase
May 3, 2021

Like ordering from you guys

Carolyn M Verified Purchase
May 3, 2021

I’d be in big trouble without this one

Becky B Verified Purchase
May 3, 2021

Best price around!

John M Verified Purchase
April 26, 2021

Works well for our dog

Barry L Verified Purchase
April 26, 2021

Great reoccurring delivery

Jennifer R Verified Purchase
January 28, 2021

We were using 75mg of Proin twice a day for our female Doberman with spay incontinence. It wasn't working by itself, but combined with Incurin (different pathways form a symbiotic relationship) we have cured her leaking!

Michele K Verified Purchase
November 24, 2020

Arrived quickly and they handled all the contact with my Vet. Huge time saver.

Gretchen s Verified Purchase
November 23, 2020

They are inexpensive and fast to fill the order

Robin B Verified Purchase
October 2, 2020

This medicine has allowed my old dog to be I the house without fear of her dripping urine. Great medicine at a great price.

Faride S Verified Purchase
August 28, 2020

Allivet has always been the website where I purchase all my pets medication at the medication prices are very affordable compared to other websites.

Richard R Verified Purchase
August 26, 2020

Helped our 15 year old Airedale. She feels better and has better control. Not bad for an older dog. Thank you

Thomas S Verified Purchase
August 21, 2020

Allivet has become our choice for all our pet medication needs. Their prices and customer service are incredible!

James T Verified Purchase
August 10, 2020

Allivet for The Win! They came through for me when Petco and Chewy told me they couldn’t fill my orders due to lack of product: Petco kept screwing up my Rx and would take weeks to figure it out. I tell everyone I run into that Allivet can fill their needs and get their pets taken care of.

Debbie M Verified Purchase
July 22, 2020

Quick shipping, good price- customer service was super helpful.

Nancy C Verified Purchase
July 8, 2020

Incurin is used with Proin to control urinary incontinence. Allivet had the best prices and good service once they received the Rx from my vet.

KELSEY I Verified Purchase
May 5, 2020

I have a 12 y/o husky who started to develop incontinence and was getting constant bladder infections. My vet put her on a urinary prescription diet as well as Proin & Incurin and she's been great! She is currently down to just one pill a day. These pills are great because they're super tiny & easy to hide with treats.

Carol L Verified Purchase
May 5, 2020

This is exactly what my older female German Shepherd needed and I didn't have to go to a vet, and that it sits at a price I can afford. Very happy

Susie L Verified Purchase
April 7, 2020

Our 15 year old shepherd suffers from kidney disease. INCURIN has made her life and mine much easier allowing her to hold her urine until she gets outside!

Linda W Verified Purchase
March 10, 2020

Stops Blatter leakage

Sandy M Verified Purchase
March 3, 2020

Awesome prices and they ship very quick to.

Kathi K Verified Purchase
February 6, 2020

convenience, esp auto refill

Katherine S Verified Purchase
January 20, 2020

Excellent price and service!

Blair U Verified Purchase
January 20, 2020

We have a twelve year old lab and this product is great for her incontinence. If your dog is having similar issues, I couldn’t recommend a better product. Ask your Vet!

Samantha S Verified Purchase
December 10, 2019

We have an 8 yr old female Greyhound who started leaking while she was sleeping/relaxing. Our vet suggested female incontinence. Proin was RX’d but she had a severe allergic reaction so we tried a cranberry bladder supplement for a few months but moved to the Incurin. It’s been fantastic! Not only had the leaking stopped but she is so much more affectionate and bubbly!

Stella k Verified Purchase
December 10, 2019

It has helped my 12 yr old Boxer and have been able to cut back the meds.

Patricia R Verified Purchase
December 4, 2019

I love Allivet! best prices! best customer service!

Frank s Verified Purchase
November 12, 2019

good for abby

Carol E Verified Purchase
October 28, 2019

Orders come quickly. So far i have not had any issues with out of stock for weeks at a time!

Allison a Verified Purchase
October 10, 2019

All purchased at Vets Rx. Expensive so I hope it works

Angelee E Verified Purchase
October 10, 2019

GREAT PLACE TO SHOP!!!!!!!!!!!!

Nancy K Verified Purchase
September 17, 2019

This site is awesome!

Ines A Verified Purchase
September 17, 2019

For my dog's incontinence. Works wonderfully.

Romaine C Verified Purchase
September 17, 2019

Fast service, best prices.

Nino c Verified Purchase
August 12, 2019

Great service

Jennifer R Verified Purchase
July 22, 2019

Love it!

Nicole W Verified Purchase
July 22, 2019

Help my dog baby

Paula K Verified Purchase
July 10, 2019

I bought this product from Allivet as it is cheaper than buying it from my vet and their quick convenient delivery to my door is awesome.

Angia P Verified Purchase
July 10, 2019

These work well and consistently for our 17 year old Border Collie. Our vet actually referred me to Allivet online and their prices are very good.

Shelley r Verified Purchase
June 25, 2019

This is a great medication for senior spayed dogs with urinary incontinance.

Michael O Verified Purchase
June 17, 2019

Great price

Stephanie W Verified Purchase
June 12, 2019

This hormone pill resolved our Dane's incontinence within a day of taking. Since she will be taking this medicine from this point forward, we are thankful to receive a discount by purchasing from Allivet.

Chuck b Verified Purchase
June 4, 2019

works great

Clare M Verified Purchase
May 29, 2019

I have used this product for four years and after the prescription is approved the meds appear within days and are very effective.

Nicole L Verified Purchase
May 22, 2019

Cured leaky bladder!

Jeri S Verified Purchase
May 1, 2019

Works well

JOSEPH R Verified Purchase
April 22, 2019

Best price around

Danielle H Verified Purchase
March 25, 2019

We've been using this for 2 years now and our black lab/pit mix has not had any more issues with spay incontinence. Tiny tablets make it easy to disguise in her food.

Lori J Verified Purchase
March 14, 2019

After the money I saved from buying for my 1st dog I decided to see how much I could save for my girl. 3 months worth is 10.00 less then the 2 months worth I am getting from a local pharmacy. This is such a better deal. I really appreciate it. Also They will notify the vet I need a refill.

Deborah e Verified Purchase
February 26, 2019

Dog was having incontinence. This seems to work to control it. Good price compared to what the vet charges.

Gina W Verified Purchase
February 15, 2019

They are always available to talk with you today, I used the live chat and was able to complete my order. Easy as 1, 2, 3

Mindy D Verified Purchase
February 15, 2019

Fast delivery and price great

Lynn K Verified Purchase
February 12, 2019

I've been using Allivet for my dog's Incurin prescription for a couple of years now, they are always fast to ship, very efficient & you can actually speak with a live knowledgeable person if you need to !! ! save at least 40% per refill when purchased thru Allivet.

Carey M Verified Purchase
February 8, 2019

This works really well for my geriatric girl. Helps control bladder leakage, and I love auto ship!

Rhonda R Verified Purchase
February 8, 2019

recommended by our vet!

Kim S Verified Purchase
January 30, 2019

I bought this medication for my older female dog, because she was leaking urine when she was sleeping. It has really helped her with no side effects:). She periodically wakes with alittle dampness on her blanket but nothing like before she started taking this medicine.

Nancy M Verified Purchase
January 30, 2019

I ordered Sierra’s medication and had it in a couple of days. I also set up auto shipment so I don’t run out of her medication. It was so easy and the people were so nice and helpful. Love Allivet

Deborah M Verified Purchase
January 21, 2019

Works for Penny, my dog.

Adrieanne M Verified Purchase
December 26, 2018

For spay urinary incontinence

Jeanine T Verified Purchase
December 19, 2018

Excellent cost

Mara S Verified Purchase
December 14, 2018

So far, they get 5 stars....but I only just placed the order. I will update my review when i receive it. The ordering process was super easy!

Tana S Verified Purchase
December 13, 2018

Price is much lower than I paid at the vets office. Shipping is always dependable and the Allivet staff always tries hard to please.

Janice P Verified Purchase
November 28, 2018

My mini Aussie is 15 1/2 years old. She started leaking urine. Had her urine tested for UTI, but no. So instead of going thru a bunch of expensive tests, I asked the Vet to give her an incontinence med. She prescribe this and it works! So happy as the doggy diapers would NOT stay on!

Laura B Verified Purchase
November 19, 2018

My dog does not tolerate Proin, and Incurin was recommended by my vet. Hoping for the best for her urinary incontinence.

Julie S Verified Purchase
November 19, 2018

The prices are over 1/2 as much as other sites. Shipping was fast.

Lacie C Verified Purchase
November 12, 2018

I really can't tell if this does a lot for my dog, but we keep her on in case it does.

Stephanie B Verified Purchase
November 12, 2018

Allivet always has the lowest prices and I always get my order a few days earlier than expected.

Teresa P Verified Purchase
November 7, 2018

best price

Shannon J Verified Purchase
October 31, 2018

only product that keeps my dog from messing in the house. works great!

Jason M Verified Purchase
October 24, 2018

Simple, seamless, and fantastic. I have this on automatic renew and if come like clockwork! I highly recommend it!

Sylvie l Verified Purchase
October 23, 2018

works great for my 14 year old Westie!

Rebecca V Verified Purchase
October 12, 2018

This product helps older, spayed, female dogs with incontinence problems. It works well!

Elena P Verified Purchase
September 28, 2018

My dog suffers from small leakage issues and Incurin keeps her from having accidents which makes me very happy. Incurin works so much better than Proin.

Questions & Answers