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LongRange (Eprinomectin) Rx

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LongRange (Eprinomectin) Rx

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This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

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Product Overview

There’s only one extended-release injectable dewormer to protect your cattle
for up to 150 days1
: LONGRANGE® (eprinomectin). In a single dose,
LONGRANGE provides up to 150 days of control for the most economically
devastating internal and external parasites.

Let your herd graze on pasture with parasite protection from LONGRANGE
dewormer, and you’ll see greater average daily gain,2 more successful
reproduction3 and better returns on sale day.
2,3 Control parasites from the
start and let your herd roam confidently.
LONGRANGE dewormer is available by prescription only.


IMPORTANT SAFETY INFORMATION: Do not treat within 48 days of
slaughter. Not for use in female dairy cattle 20 months of age or older,
including dry dairy cows, or in veal calves. Not for use in breeding bulls,
or in calves less than 3 months of age. Not for use in cattle managed in
feedlots or under intensive rotational grazing. Post-injection-site
reactions (e.g., granulomas, necrosis) can occur, but typically resolve
without treatment. Pregnant women should wear gloves and exercise
caution or avoid handling this product.

LongRange (Eprinomectin) is the first extended-release injectable cattle dewormer that provides cattle producers season-long persistent control of parasites in cattle for 100 to 150 days in a single dose, dependent on parasite species.
Cattle
- Treat internal and external parasites in cattle. - Provides parasite control in cattle. - Keep Cattle on pasture safe and protected from parasites. - Protects cattle from parasites like Gastrointestinal Roundworms. - Protects cattle from parasites like Lungworms.
LONGRANGE™ (eprinomectin) is a ready-to-use, sterile injectable preparation containing eprinomectin, a member of the macrocyclic lactone class of antiparasitics. Each mL of LONGRANGE contains 50 mg of eprinomectin in a co-solvent system of N-methyl-2-pyrrolidone (30% v/v) and triacetin (qs), along with 50 mg of poly-lactide-co-glycolic-acid 75:25 (PLGA), a polymer that allows a slow release of eprinomectin from the formulation, thereby maintaining a prolonged duration of product effectiveness.
The product is likely to cause tissue damage at the site of injection, including possible granulomas and necrosis. These reactions have disappeared without treatment. Local tissue reaction may result in trim loss of edible tissue at slaughter. Observe cattle for injection site reactions. If injection site reactions are suspected, consult your veterinarian. This product is not for intravenous or intramuscular use.
Eprinomectin 5% Sterile Solution
Contact your nearest emergency animal hospital.
- Not for use in breeding bulls, or in calves less than 3 months of age. - Not for use in cattle managed in feedlots or under intensive rotational grazing. - Not for use in female dairy cattle 20 months of age or older, including dry dairy cows. Not for use in calves to be processed for veal.
100 ml 250 ml 500 ml
Boehringer Ingelheim
LONGRANGE effectively controls all stages of cattle grubs. However, proper timing of treatment is important. For the most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season. Destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions, including the possibility of fatalities. Killing Hypoderma lineatum when it is in the tissue surrounding the esophagus (gullet) may cause salivation and bloat; killing H. bovis when it is in the vertebral canal may cause staggering or paralysis. These reactions are not specific to treatment with LONGRANGE, but can occur with any successful treatment of grubs. Cattle should be treated either before or after these stages of grub development. Consult your veterinarian concerning the proper time for treatment.

DOSAGE AND ADMINISTRATION 
  • Administer subcutaneously in front of the shoulder at the
    recommended dose of 1 mL per 110 lbs. of body weight (1 mg
    eprinomectin/kg).
  • Divide doses greater than 10 mL between two injection sites.
  • Use sterile needles (16- or 18-gauge, ½ to ¾ inch).
  • Available in 100-mL, 250-mL and 500-mL glass bottles.
  • Do not underdose; calculate dosage based on current body weight.
 


Longrange Dosage

Body Weight (lb)

Dose Volume (mL)

110

1

220

2

330

3

440

4

550

5

660

6

770

7

880

8

990

9

1100

10

 
The product is likely to cause tissue damage at the site of injection, including possible granulomas and necrosis. These reactions have disappeared without treatment. Local tissue reaction may result in trim loss of edible tissue at slaughter. Observe cattle for injection site reactions. If injection site reactions are suspected, consult your veterinarian. This product is not for intravenous or intramuscular use

 

 

LONGRANGE (eprinomectin) is a ready-to-use, sterile injectable preparation containing eprinomectin, a member of the macrocyclic lactone class of antiparasitics.
 
Each mL of LONGRANGE contains 50 mg of eprinomectin in a co-solvent system of N-methyl-2-pyrrolidone (30% v/v) and triacetin (qs), along with 50 mg of poly-lactide-co-glycolic-acid 75:25 (PLGA), a polymer that allows a slow release of eprinomectin from the formulation, thereby maintaining a prolonged duration of product effectiveness. Butylated hydroxytoluene (0.2 mg/mL) acts as an antioxidant in the formulation.
 

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LongRange (Eprinomectin) Description

There’s only one extended-release injectable dewormer to protect your cattle
for up to 150 days1
: LONGRANGE® (eprinomectin). In a single dose,
LONGRANGE provides up to 150 days of control for the most economically
devastating internal and external parasites.

Let your herd graze on pasture with parasite protection from LONGRANGE
dewormer, and you’ll see greater average daily gain,2 more successful
reproduction3 and better returns on sale day.
2,3 Control parasites from the
start and let your herd roam confidently.
LONGRANGE dewormer is available by prescription only.


IMPORTANT SAFETY INFORMATION: Do not treat within 48 days of
slaughter. Not for use in female dairy cattle 20 months of age or older,
including dry dairy cows, or in veal calves. Not for use in breeding bulls,
or in calves less than 3 months of age. Not for use in cattle managed in
feedlots or under intensive rotational grazing. Post-injection-site
reactions (e.g., granulomas, necrosis) can occur, but typically resolve
without treatment. Pregnant women should wear gloves and exercise
caution or avoid handling this product.

What is LongRange (Eprinomectin)?
LongRange (Eprinomectin) is the first extended-release injectable cattle dewormer that provides cattle producers season-long persistent control of parasites in cattle for 100 to 150 days in a single dose, dependent on parasite species.
Which animals/pets is LongRange (Eprinomectin) for?
Cattle
LongRange (Eprinomectin) uses
- Treat internal and external parasites in cattle. - Provides parasite control in cattle. - Keep Cattle on pasture safe and protected from parasites. - Protects cattle from parasites like Gastrointestinal Roundworms. - Protects cattle from parasites like Lungworms.
What does LongRange (Eprinomectin) do?
LONGRANGE™ (eprinomectin) is a ready-to-use, sterile injectable preparation containing eprinomectin, a member of the macrocyclic lactone class of antiparasitics. Each mL of LONGRANGE contains 50 mg of eprinomectin in a co-solvent system of N-methyl-2-pyrrolidone (30% v/v) and triacetin (qs), along with 50 mg of poly-lactide-co-glycolic-acid 75:25 (PLGA), a polymer that allows a slow release of eprinomectin from the formulation, thereby maintaining a prolonged duration of product effectiveness.
LongRange (Eprinomectin) side effects
The product is likely to cause tissue damage at the site of injection, including possible granulomas and necrosis. These reactions have disappeared without treatment. Local tissue reaction may result in trim loss of edible tissue at slaughter. Observe cattle for injection site reactions. If injection site reactions are suspected, consult your veterinarian. This product is not for intravenous or intramuscular use.
LongRange (Eprinomectin) ingredients
Eprinomectin 5% Sterile Solution
LongRange (Eprinomectin) overdose: What to do?
Contact your nearest emergency animal hospital.
What to know before using LongRange (Eprinomectin)
- Not for use in breeding bulls, or in calves less than 3 months of age. - Not for use in cattle managed in feedlots or under intensive rotational grazing. - Not for use in female dairy cattle 20 months of age or older, including dry dairy cows. Not for use in calves to be processed for veal.
How is LongRange (Eprinomectin) sold?
100 ml 250 ml 500 ml
Manufacturer
Boehringer Ingelheim
Tips for using LongRange (Eprinomectin)
LONGRANGE effectively controls all stages of cattle grubs. However, proper timing of treatment is important. For the most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season. Destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions, including the possibility of fatalities. Killing Hypoderma lineatum when it is in the tissue surrounding the esophagus (gullet) may cause salivation and bloat; killing H. bovis when it is in the vertebral canal may cause staggering or paralysis. These reactions are not specific to treatment with LONGRANGE, but can occur with any successful treatment of grubs. Cattle should be treated either before or after these stages of grub development. Consult your veterinarian concerning the proper time for treatment.
Overview

DOSAGE AND ADMINISTRATION 
  • Administer subcutaneously in front of the shoulder at the
    recommended dose of 1 mL per 110 lbs. of body weight (1 mg
    eprinomectin/kg).
  • Divide doses greater than 10 mL between two injection sites.
  • Use sterile needles (16- or 18-gauge, ½ to ¾ inch).
  • Available in 100-mL, 250-mL and 500-mL glass bottles.
  • Do not underdose; calculate dosage based on current body weight.
 


Longrange Dosage

Body Weight (lb)

Dose Volume (mL)

110

1

220

2

330

3

440

4

550

5

660

6

770

7

880

8

990

9

1100

10

 
The product is likely to cause tissue damage at the site of injection, including possible granulomas and necrosis. These reactions have disappeared without treatment. Local tissue reaction may result in trim loss of edible tissue at slaughter. Observe cattle for injection site reactions. If injection site reactions are suspected, consult your veterinarian. This product is not for intravenous or intramuscular use

 

 

Main Ingredients
LONGRANGE (eprinomectin) is a ready-to-use, sterile injectable preparation containing eprinomectin, a member of the macrocyclic lactone class of antiparasitics.
 
Each mL of LONGRANGE contains 50 mg of eprinomectin in a co-solvent system of N-methyl-2-pyrrolidone (30% v/v) and triacetin (qs), along with 50 mg of poly-lactide-co-glycolic-acid 75:25 (PLGA), a polymer that allows a slow release of eprinomectin from the formulation, thereby maintaining a prolonged duration of product effectiveness. Butylated hydroxytoluene (0.2 mg/mL) acts as an antioxidant in the formulation.
 

Long Range (Eprinomectin)

 

                                Whether we like it or not, parasites are a fact of life for our livestock and for us. All living things on Earth including many parasites themselves play host to one or more exploitative organisms that live on or inside them, from microscopic protozoan to tapeworms reaching a nauseating 20 feet in length. Parasites make up the majority of species on our planet, and a number of them are justly feared because of the human diseases they cause such as malaria, African sleeping sickness and trichinosis. Not all parasites, however, pose a risk to us, or our animals. Indeed, a parasite that kills its host is pretty unsuccessful at the game of survival. In wild animals, a delicate balance between host and parasite seems to be the general rule. When working out a worm prevention program on your farm, it helps to realize that each parasite species has a unique life cycle.

 

                In general, mature, healthy livestock, like their wild counterparts develop a degree of immunity to parasites, while young and old animals, and those under the stress of pregnancy, lactation, malnutrition or overcrowding are more likely to suffer ill effects from parasitism. A pasture’s parasite load and thus the worm levels in the animals that feed on it will vary with the seasons, weather conditions and farm management practices. Worms like warm, moist environments so parasite levels tend to peak during spring and plummet during dry summer months, for instance.

 

Signs of parasite infestation include:

·         Weight loss

·         Depression

·         Rough hair coat

·         Diarrhea

·         Anemia

 

Long Range is a ready to use, sterile injectable preparation containing Eprinomectin, a member of the macrocyclic lactone class of antiparasitics. Eprinomectin is a semi-synthetic compound of the avermectin family, intended for the treatment of internal and external parasites in cattle and in lactating cows. It has been proven to effectively protect cattle from re-infection from gastrointestinal roundworms such as Cooperia oncophora, Cooperia punctata, Trichostrongylus axei in 100 days and Haemonchus placei, Oesophagostomum radiatum, Ostertagia lyrata, Ostertagia ostertagi in 120 days. Also, from lungworms such as Dictyocaulus viviparous in 150 days.

 

Long Range should be administered only by subcutaneous injection in front of the shoulder at the recommended dosage level of 1mg Eprinomectin per kg body weight. Each milliliter of Long Range contains 50 mg of Eprinomectin, which is sufficient to treat 110 lbs of bodyweight. Doses greater than 10 mL should be divided between two injection sites to reduce occasional discomfort or site reaction. Underdosing and/or subtherapeutic concentrations of extended-release anthelmintic products may encourage the development of parasite resistance.

 

Animals intended for human consumption must not be slaughtered within 48 days of the last treatment. This drug product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. It is indicated through studies that when Eprinomectin comes in contact with soil, it binds to the soil and becomes inactive over time. Free Eprinomectin may affect fish and certain aquatic organisms; it is suggested to dispose of containers in an approved landfill or by incineration. Eprinomectin is excreted in the feces of treated animals; it can inhibit the reproduction and growth of pests and beneficial insects that use feces as a source of food and for reproduction. It is recommended that parasite resistance be monitored following the use of any anthelmintic with the use of a fecal egg count reduction test program.

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