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Zenrelia (ilunocitinib) Tablets for Dogs

By Zenrelia
(14 reviews)
Veterinary Diet Item
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Zenrelia (ilunocitinib) Tablets for Dogs

By Zenrelia
$2.18
One-time purchase
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Product Overview

Zenrelia is a JAK-inhibitor, that is highly rated by vets and pet owners, for the control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. Zenrelia is a flavorless, oral tablet given once daily with or without food, from the comfort of home.

Indications
Zenrelia is a prescription medication used to control itching and inflammation associates with skin allergies for dogs over 12 months of age.

IMPORTANT SAFETY INFORMATION
See package insert including the Boxed Warning. For full prescribing information speak with your veterinarian, call 1-88-545-5973, or visit www.elancolabels.com/us/zenrelia.

WARNING: VACCINE-INDUCED DISEASE AND INADEQUATE IMMUNE RESPONSE TO VACCINES. Based on results of the vaccine response study, dogs receiving Zenrelia are at risk of fatal vaccine-induced disease and inadequate immune response to vaccines. Dogs should not take Zenrelia for a time period before and after vaccination. Discuss your dog’s vaccine schedule with your veterinarian. Dogs should be up to date on vaccinations prior to starting Zenrelia. Do not use in dogs less than 12 months old or with a serious infection. Dogs should be monitored for the development of infections because Zenrelia may increase the chances of developing an infection. Neoplastic conditions (benign and malignant) were observed during clinical studies. The most common side effects were vomiting, diarrhea and tiredness. Zenrelia has not been tested in dogs used for breeding, pregnant, or lactating dogs and has not been evaluated in combination with glucocorticoids, cyclosporine, or other immune suppressive drugs.

Dogs (12 months of age or older)
Innovative treatment, with once daily dosing from the start. Works fast, visible improvements from day one. Continuous Efficacy: No rebound itch due to changing doses. In a head to head clinical trial with Apoquel, 77% of Zenrelia-treated dogs achieved PVAS <2 compared to 53% of Apoquel-treated dogs. Reduces inflammation and improves skin lesions.
Zenrelia blocks itch signals from reaching your dog's brain, reducing the sensation of itch.
Monitor your pet for any adverse reactions, includeing vomiting, diahrea and lethargy. Contact your veterinarian with any quesitons you might have.
ilunocitinib
Contact your nearest emergency animal hospital.
IMPORTANT SAFETY INFORMATION: See package insert including the Boxed Warning. For full prescribing information speak with your veterinarian, call 1 888 545 5973 or visit https://www.elancolabels.com/us/zenrelia. WARNING: VACCINE-INDUCED DISEASE AND INADEQUATE IMMUNE RESPONSE TO VACCINES. Based on results of the vaccine response study, dogs receiving Zenrelia are at risk of fatal vaccine-induced disease from modified live virus vaccines and inadequate immune response to any vaccine. Discontinue Zenrelia for at least 28 days to 3 months prior to vaccination and withhold Zenrelia for at least 28 days after vaccination. Dogs should be up to date on vaccinations prior to starting Zenrelia. Do not use in dogs less than 12 months old or dogs with a serious infection. Dogs should be monitored for the development of infections because Zenrelia may increase the chances of developing an infection. Neoplastic conditions (benign and malignant) were observed during clinical studies. The most common side effects were vomiting, diarrhea and tiredness. Zenrelia has not been tested in dogs used for breeding, pregnant, or lactating dogs and has not been evaluated in combination with glucocorticoids, cyclosporine, or other immune suppressive drugs.
Sold in strengths of 4.8 mg, 6.4 mg, 8.5 mg or 15 mg in 1 count, 30 count bottle or 90 count bottle.
Elanco
Use as directed by your Veterinarian.
Active Ingredient : ilunocitinib

About This Product

Customer Reviews

5.0
14 reviews
5 14
4 0
3 0
2 0
1 0
Paul G Verified Purchase
October 2, 2026

My dog is a Boxador, and her allergies are bad. This is the only medication that has worked for her without any side effects.

Susan A Verified Purchase
October 2, 2026

Zenrelia really scratches the itch!

I tried almost everything to stop my dog, Rosie, from itching. Both Rosie and I were so relieved (Rosie literally) when my vet gave her Zenrelia. She stopped scratching, biting, and licking herself obsessively. Now, she’s a normal happy dog. I would recommend Zenrelia to anyone who loves their itchy pooches.

Krystal G Verified Purchase
September 24, 2026

Banditos itch relief

My poor big boy would chew his tail till it bled. We started zenrelia a few months ago and once we got the dosage right ( he is a really big boy, 120lbs) he started doing really good with it. It has stopped the excessive chewing and it is alot cheaper than some others we have tried.

Kathleen T Verified Purchase
September 24, 2026

Zenrelia vs. Apoquel

Our dog was on Apoquel for years and we recently switched to Zenrelia at our veterinarian's recommendation. He seems to be doing well, no side effects. Zenrelia is more affordable and very easy to manage with Allivet. The medication is on auto-renew so we receive it promptly every 2weeks! Allivet sends a first eMail alerting to the debit, a second confirming shipping address, and then tracking when the package is in transit. Thank you Allivet!

Barb W Verified Purchase
August 31, 2026

Worked smoothly

Steve
August 18, 2026

Worked great. Dog had allergies and was licking his paws red, scratching fur off his ears, and rubbing his runny, itchy eyes on the furniture. After a couple of weeks on Zenrelia, it all cleared up. Not sure I want him on the drug permanently, so I'll wait to see if problem flares up again for next round.

Patricia H Verified Purchase
July 27, 2026

Works good

Tried several medications that did not work fo r my pet until Zenralia.

Kesia C Verified Purchase
July 15, 2026

Immediately helped my dog

This medicine immediately calmed my dogs allergies when OTC meds were failing and he was miserable and the other prescription was too expensive.It's signigicantly cheaper than the other script.

Henry B Verified Purchase
July 11, 2026

Good

Susanne F Verified Purchase
July 8, 2026

Save money, buy online

Our Wally needs Zenrelia to relieve his itches. I used to buy Apoquel for him from our vet but it was expensive. After researching alternatives, I found Zenrelia for almost half the price on Allivet. Now we get auto shipments once a month and the pills help our pup. What more could you ask for? Give them a try.

Christina N Verified Purchase
June 9, 2026

It works!

My Frenchie has struggled for years with skin allergies. Zenrelia is the only thing that seems to work well. No more redness, itching, and minimal paw licking.

Nicki K Verified Purchase
June 7, 2026

It was night and day after putting my dog on this. He went from red, itchy, losing hair and just miserable - to a happy itch free dog. 10/10 recommend for dogs with allergies

Synthia m
May 3, 2026

I recently switched from using apoquel to zenirelia and am so glad I did! My dog is 100% better from the first pill he took! He is no longer scratching like before, he occasionally does have the licking of the paws and the inside of his legs but not like before. I am so thankful my vet suggested this to me.

Kelly M
August 5, 2025

My pup was on a different allergy med for a very long time. I thought there were no better options. This worked so much better and was way cheaper!

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