Advantage Multi vs K9 Advantix II

An essential part of keeping your dog happy and healthy is keeping dangerous and irritating fleas and pests at bay. Two of the best options for protecting your dog from parasites are Advantage Multi and K9 Advantix II. Each unique product works in a different way to tackle infestations, and they each offer advantages that might aid in your decision. See below for a table and additional information about these two top-quality treatment options!

Advantage Multi for Dogs

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Heartgard Plus for Dogs

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What are the differences between Advantage Multi and K9 Advantix II?

At a glance, it might appear that these two incredible treatments are pretty similar. After all, they are both topical flea treatments. Each option is safe for puppies 7 weeks and up (Advantage Multi may be used on puppies weighing a minimum of 3 pounds, and K9 Advantix II a minimum of 4 pounds).

Neither product has been proven safe for use in pregnant, lactating, or breeding dogs. Another major similarity is that both medications begin killing fleas within 12 hours. Finally, both products are administered monthly.

Now that we’ve highlighted the similarities between these products, let’s discuss the many differences. One of the key differences are the active ingredients in each formula. Advantage Multi contains Moxidectin and Imidacloprid, while K9 Advantix II combines Pyriproxyfen, Imidacloprid, and Permethrin. K9 Advantix II is an over-the-counter product, and Advantage Multi requires a prescription.

Each product offers broad-spectrum parasite protection. In addition to fleas, both products protect against other pests. Advantage Multi prevents heartworm disease, hookworms, roundworms, and ear mites. K9 Advantix II doesn’t just kill fleas - it also repels them and kills them in the larvae and egg stages. It also kills and repels ticks and mosquitoes, repels biting flies, and treats lice. Neither product is formulated for use in cats.

Key takeaways on Advantage Multi vs. K9 Advantix II

As you can tell from the many impressive advantages, you can’t go wrong with either of these amazing products. However, there are a few ways to make a decision that best suits your dog. To make the best choice for your dog, there are just a couple of considerations to weigh. Do you prefer an over-the-counter treatment option, or would you like a prescription medication? If you’re searching for an over-the-counter product, K9 Advantix II is a great choice. If you’d like a prescription, opt for Advantage Multi.

Is your dog already taking a heartworm preventative? If not, your veterinarian will likely recommend that you choose a product to protect your dog against this deadly disease.

Feature Advantage Multi K9 Advantix II
Kills Fleas Yes Yes
Repels Fleas No Yes
Kills Flea Eggs and Larvae No Yes
Kills Ticks No Yes
Repels Ticks No Yes
Repels Mosquitoes No Yes
Prevents Heartworm Yes No
Other Parasites Ear mites, roundworms, and hookworms Lice & Biting Flies
Waterproof Yes Yes
How Long to work Begins to kill fleas within 12 hours 12 hours to kill fleas
Taste N/A N/A
Active Ingredient Imidacloprid and Moxidectin Permethrin, Imidacloprid, and Pyriproxyfen
RX Required Yes No
Application Type Topical Topical
Dosing 1 application per month Monthly application
Age Dogs 7 weeks and older that weight at least 3 pounds Puppies 7 weeks and older and weighing more than 4 lbs.
Manufacturer Bayer Animal Health Bayer Animal Health
Safety Speak to your vet about risks associated with breeding, pregnant, or lactating dogs Don't apply to cats

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