Comfortis vs Advantage Multi

Parasites aren’t just irritating - they can also be dangerous. Pet parents might become overwhelmed as they begin to research the many flea amd tick treatments available. Two of the most-loved options are Comfortis Chewable Tablets and Advantage Multi.These products are comparable in many ways, but they are also unique. Keep reading for a table and more information to help you make an informed decision!

How is Comfortis different from Advantage Multi?

For starters, Comfortis is a once-monthly oral flea medication. It works to kill fleas within 30 minutes on cats or dogs 14 weeks old and up. Advantage Multi is a once-monthly topical topical flea medication that starts killing fleas within 12 hours. It offers added protection against heartworms, hookworms, roundworms, and ear mites on dogs over the age of 7 weeks weighing over 3 pounds.

Comfortis contains Spinosad, while Advantage Multi uses Moxidectin and Imidacloprid. Neither medication is formulated specifically for use in pregnant, breeding, or lactating dogs, so you should ask your veterinarian about the best course of treatment if your dog falls under any of those categories. Both of these treatments require a prescription from your veterinarian.

What should I consider when choosing Comfortis or Advantage Multi for my dog?

If you’re searching for an excellent flea treatment for your pet, and if your pet is over the age of 14 weeks, Comfortis may be a great choice for you and your cat or dog. If you’re searching for a more broad-spectrum product that includes protection against intestinal parasites, Advantage Multi is an excellent option. Advantage Multi is also a wonderful way to protect dogs who are too young to use Comfortis (between the ages of 7 and 14 weeks).

Now that you’re familiarized yourself with these two top-quality products, the next step is to see your veterinarian. Your vet will evaluate your pet and help you decide which treatment is best. If you have any additional concerns or questions about oral flea and tick treatments, you are invited to reach out to the Allivet pharmacists for pet parent counseling!

Feature Comfortis Advantage Multi
Kills Fleas Yes Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No No
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm No Yes
Other Parasites No Ear mites, roundworms, and hookworms
Waterproof Yes since taken orally Yes
How Long to work Begins to kills fleas in 30 minutes Begins to kill fleas within 12 hours
Taste Beef flavored N/A
Active Ingredient Spinosad Imidacloprid and Moxidectin
RX Required Yes Yes
Application Type Chewable Tablet Topical
Dosing 1 tablet per month 1 application per month
Age Dogs and cats 14 weeks and older Dogs 7 weeks and older that weight at least 3 pounds
Manufacturer Elanco Animal Health Bayer Animal Health
Safety Not evaluated for safe use in breeding, pregnant, and lactating dogs. Speak to your vet about risks associated with breeding, pregnant, or lactating dogs