Nexgard vs Simparica

You are the highlight of your precious pet's life and so it makes sense you'll want to give them the quality of life that supports you both, with Allivet we're here to help you find the right flea and tick treatment for your dog or cat. We have two popular treatment plans that we'll look through today, Simparica Chewable Tablets and Nexgard Chewable Tablets. This guide will help you through the pros and cons of each in order to find what best suits you and your pets needs.

Simparica

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Nexgard for Dogs and Puppies

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What are the differences between Simparica and Nexgard

Both Simparica and Nexgard are chewable tablets, Liver flavored for Simparica and Beef for Nexgard. The main differences between the two are the strength and speed at which the products work, with Simparica killing fleas in little as 3 hours and ticks within 8. Nexgard offers a 4 hour time frame for killing fleas while killing ticks in 24 hours. Simparica however must be administered safely to dogs that are at least 6 months old, while Nexgard can be safely administered at 8 weeks.

Both Nexgard and Simparica use a pesticide from the same Isoxazoline class to treat fleas and ticks. Nexgard uses Afoxoflaner and kills 100% of fleas in 24 hours. Simparica uses Sarolaner which over stimulates the nervous system of the pests which kill fleas and ticks. Nexgard is the only FDA approved option for preventing infections that cause Lyme disease.

Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. While Simparica was trialed and not approved, Nexgard has not yet been evaluated for use in breeding, pregnant, or lactating dogs. Nexgard chewable tablets and Simparica are not available for cats.

Simparica and Nexgard require a prescription from your veterinarian before they can be purchased. Your vet should be able to answer any questions related to side effects, precautions, or special care for your dog.

Final Thoughts on Simparica vs Nexgard

Overall, the costs for Nexgard and Simparica place Simparica as the least costly between the two. Since you can't start Simparica until 6 months, some pet owners may start with Nexgard and then switch to Simparica when able. Additionally, some pet owners may opt to switch over to alternatives such as Bravecto Chewable Tablets to protect breeding, pregnant, and lactating dogs.

If you still have questions on which oral flea and tick treatment is best suited for your pets needs, our veterinarians are standing by to assist you.

Feature Simparica NexGard
Kills Fleas Yes Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No Yes
Kills Ticks Yes Yes
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm No No
Protects Against Other Parasites No No
Waterproof Yes - taken orally Yes - taken orally
How Long to Work Kills fleas within 3 hours and tickets within 8 hours. 4 hours to kill fleas and 24 hours hours to kill ticks
Taste Liver Beef Flavored
Active Ingredient Sarolaner Afoxolaner
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age Dogs 6 months and older weighing at least 2.8 pounds Puppies 8 weeks and older and weigh more than 4 lbs
Manufacturer Zoetis Boehringer Ingelheim
Safety Not approved for breeding, pregnant, and lactating dogs Not yet evaluated for use of in breeding, pregnant, or lactating dogs.