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Product Overview

How To Use

What’s in it?



Questions & Answers

Product Description

Epizyme is raw whole activated pancreas. It contains a concentrate of pancreatic enzymes of porcine origin with standardized lipase, protease, and amylase activities along with peptidases, nucleases, elastase, and esterases.

What is EPIZYME Powder?

Epizyme Powder, is a digestive aid given to dogs and cats suffering from pancreatic insufficiency. Epizyme aids in replacement therapy where digestion of carbohydrates, fats, and proteins is inadequate due to exocrine pancreatic insufficiency. Epizyme pet meds replaces the lipase, protease, and amylase that your pets are missing during digestion, improves nutrient absorption, and reduces the symptoms of pancreatic deficiencies.

Who is EPIZYME Powder for?

Epizyme is intended for use only in cats and dogs.

Why use EPIZYME Powder?

  • Aids in improved fat, carbohydrate, and protein digestion for animals experiencing pancreatic insufficiency
  • Is simple to administer
  • Can help with weight management for pets

How does EPIZYME Powder work?

Epizyme contains three enzymes: amylases, lipases, and proteases. These enzymes help with improved protein, carbohydrate and fat digestion.


Vet Brands International, Inc.

Active ingredient(s):

  • Lipases
  • amylases
  • proteases

How is EPIZYME Powder sold?

8oz Powder 12oz Powder

What are the side effects of EPIZYME Powder?

Stop administering Epizyme and seek emergency medical care if your pet:
  • Begins showing signs of an allergic reaction
  • Has hives
  • Has difficulty breathing
  • Has tongue, face, or lip swelling

What special precautions are there?

If your pet shows sensitivity to Epizyme, discontinue use immediately.

What to do if overdose?

Contact your closest emergency pet hospital.

How can I store EPIZYME Powder?

Store in a dry and cool environment.

Helpful Tips:

    Epizyme is a powder that can be added to dry or canned dog food that has been moistened. Mix very thoroughly to ensure food particles and enzymes are combined.
  • Before feeding, allow mixture to sit for 5 minutes. The digestion process can be enhanced by allowing mixture to sit at room temperature for 15 to 20 minutes before feeding. Feed your pet 3 small meals a day while administering this medication.

Pharmacists are standing by to offer Pet Parent counseling regarding prescription medication purchased from Allivet before and after dispensing. Pharmacists on duty are available Monday-Friday, 9:30AM - 5:30PM EST and will be on call Saturday 12:00PM - 4:00PM EST for consultation.


EPIZYME powder is added to moistened dog food (canned or dry). Thorough mixing is necessary to bring the enzymes into close contact with the food particles. Allow this mixture to sit for five minutes before feeding. Incubation at room temperature for 15-20 minutes before feeding appears to enhance the digestive process. Frequent feeding, at least 3 times daily is important.
Dogs 3/4-1 teaspoonful (2.8g teaspoonful) with each meal.
Cats: 1/4-3/4 teaspoonful (2.8g teaspoonful) with each meal.

Main Ingredients


Dog Pancreatic Insufficiency

Exocrine pancreatic insufficiency is an unusual disease found in dogs except in certain breeds and symptoms can be life threatening. Weight loss, diarrhea, abnormal appetite, poor coat quality and flatulence are all symptoms that your dog may be suffering with exocrine pancreatic insufficiency. Luckily there are medications to help with dogs that cannot digest food properly due to EPI.

Viokase-V Powder is pancreatic enzymes that help improve food digestion used as a replacement therapy for dogs containing the following units: Lipase USP 8,000, Protase USP 30,000 and Amaylase USP 30,000.

Epizyme powder is activated whole raw pancreas containing standardized amylase, protease and lipase activities, all ingredients helping as a digestive aid.

Panakare Plus tablets and powder is a generic more affordable pancreatic enzyme concentrate of porcine origin fortified with the fat soluble vitamins A, D and E also containing Lipase USP 8,000, Protase USP 30,000 and Amaylase USP 30,000.

Exocrine pancreatic insufficiency can be life threatening and incurable however with the right treatment your dog can live a long and happy life.

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How much do you use per feeding for a dog weighting over 100 lbs.?

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