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Proin Rx

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Product Overview

How To Use

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Questions & Answers

Product Description

Proin is the ideal solution for dogs with incontinence issues. The proin chewable tablet contains phenylpropanolamine which is FDA approved for the management and treatment of canine urinary incontinence. Phenylpropanolamine is an adrenergic agent that tightens the bladder sphincter muscle, helping your dog control urine leakage. 

*This item can't be shipped to AR, GA, HI, IA, LA, OR or WV.

What is Proin?

Proin is a chewable tablet used for the management and treatment of urinary incontinence in dogs. Proin is manufactured by PRB Pharmacal, Inc and contains phenylpropanolamine. It is available in all states except Arkansas, Georgia, Hawaii, Iowa, Louisiana, Oregon or West Virginia, where it is classified as a controlled substance.

Who is Proin for?

Proin is for dogs experiencing urinary incontinence issues, such as urine leakage.

Why use Proin?

- Proin chewable tablets are an effective treatment for urinary incontinence in dogs. Proin ensures sustained phenylpropanolamine levels in the bloodstream and may help reduce the conditions often associated with high levels of phenylpropanolamine, such as decreased appetite, changes in heart rate, increased blood pressure, and hyperexcitability.

How does Proin work?

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the urethral sphincter muscle to help control urine leakage.


PRN Pharmacal, Inc.

Active ingredient(s):

Phenylpropanolamine Hydrochloride

How is Proin sold?

Proin Chewable tablets are available in 25mg, 50mg, and 75mg strengths as single tablets or 60 or 180 count bottles.

What are the side effects of Proin?

Phenylpropanolamine stimulates a “fight or flight” response. This means that the following side effects may be observed: increased heart rate, high blood pressure, and restlessness. Appetite loss or reduction may be a problem.

What special precautions are there?

Keep away from children and animals. Taking Proin may cause excitability and restlessness in dogs.

What to do if overdose?

In case of Proin overdose contact your veterinarian or veterinary emergency room. Symptoms of overdose may include increased thirst, urination and hunger, hyperactivity, personality change, and reduced heat tolerance.

How can I store Proin?

Store tablets at controlled room temperature 20° to 25°C (68° to 77°F). Replace cap securely after each opening

Helpful Tips:

Dog bladder infections can cause a strong urge to urinate and is a primary cause of canine urinary incontinence. Dogs with an infected bladder tend to empty the bladder partially each time that they urinate. This occurs due to a difficulty in emptying the entire urinary bladder in one go and makes the urine extremely smelly. The urine may sometimes contain blood due to severe infections caused by calculi, cancer, or a tumor.

Pharmacists are standing by to offer Pet Parent counseling regarding prescription medication purchased from Allivet before and after dispensing. Pharmacists on duty are available Monday-Friday, 9:30AM - 5:30PM EST and will be on call Saturday 12:00PM - 4:00PM EST for consultation.

Use as directed by your veterinarian. The usual dose of Proin for dogs is 0.4-0.8mg/pound every 12 hours.

Active Ingredient : Phenylpropanolamine Hydrochloride

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2 Questions 2 Answers

Questions With Most helpful Answers?

My dog is on 2 Proins per day and still wets the bed. Can this be increased and what is the danger.

1 Answer

My dog has appetite suppression on Proin 25mg at 2x/day. What can be done?

1 Answer
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