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Product Description

SETTLE for horses is a mycobacterium cell wall fraction immunostimulant. SETTLE is recommended as an aid in the treatment of equine endometritis caused by Streptococcus zooepidemicus. Sold as single 1.5 ml dose vials. See Allivet's Horse Vaccine Chart to find out which vaccine is right for your horse. *This item can't be shipped to MN. 


Settle for horses is recommended as an aid in the treatment of endometritis caused by Streptococcus zooepidemicus, it has been proven to be powerful as a stand-alone therapy, however SETTLE can be effectively integrated with standard treatment regimens that include antibiotics and uterine lavage.

SETTLE enhances the innate immune responses by activating macrophages and stimulating the cloning of polymorphonuclear leukocytes. These activated phagocytic cells stimulate a cytokine cascade that results in the destruction of bacteria, such as Streptococcus zooepidemicus.SETTLE is available in cartons containing 6 x 1.5ml single dose vials.

Some side effects that may occur while using the vaccine are mild fever, drowsiness, and decreased appetite may occur for 1 to 2 days following intravenous injection. These are normal responses to the release of IL-1. An elevated body temperature enhances the immune function by stimulating leukocyte activity and it is not an adverse side effect. Should bestored at 2°-7°C. (35°-45°F) always avoid freezing.

Settle should be used atthe diagnosis of uterine infection and while awaiting culture, in conjunction with local or systemic antibiotic
,the day after foaling in known endometritis susceptible mares or recognized as difficult breeder, also at time of retained placenta removal.

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