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Vetsulin VetPen, 10 x 2.7 ml Cartridges Rx

By Vetsulin

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Vetsulin VetPen, 10 x 2.7 ml Cartridges Description
Vetsulin VetPen Cartridge (porcine insulin zinc suspension) is approved by the FDA to reduce hyperglycemia and associated clinical signs in pets with diabetes mellitus.

Vetsulin Cartridges should only be used with VetPen Needles 12mm (29g) (#50990) and VetPens (#50992), which are sold separately.

This item ships cold.
What is Vetsulin VetPen, 10 x 2.7 ml Cartridges?
Vetsulin VetPen Cartridge, 2.7 ml (40 units per ml) (porcine insulin zinc suspension) is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs and cats with diabetes mellitus.
Which animals/pets is Vetsulin VetPen, 10 x 2.7 ml Cartridges for?
For use in cats and dogs.
Vetsulin VetPen, 10 x 2.7 ml Cartridges uses
Vetsulin is the only insulin approved by the FDA for use in diabetic pets in the United States. It is the ideal choice for your diabetic pet.
What does Vetsulin VetPen, 10 x 2.7 ml Cartridges do?
  • Porcine insulin has a similar amino acid structure to canine insulin. It is considered an intermediate acting insulin.
  • Vetsulin has two activity peaks after administration in dogs - one around 4 hours and another around 11. Activity duration varies, but is typically 14 to 24 hours.
  • In cats, the activity peak occurs between 1.5 and 8 hours, and activity duration varies at 8 to 12 hours.
  • Peak activity, activity duration, and required dose to adequately control diabetic symptoms will all vary between patients.
Vetsulin VetPen, 10 x 2.7 ml Cartridges side effects
Low blood sugar (hypoglycemia) is the most common adverse reaction to insulin. This can be serious and life-threatening. It harm the brain or heart. Serious symptoms of low blood sugar can include:
  • Blurred vision
  • Rapid heartbeat
  • Sweating
  • Shaking

    Other potential reactions include:
    • Weight gain
    • Edema (swelling)
    • Rash
    • Pruritus (itching)
    • Lipodystrophy
    • Injection site reactions
    • Allergic reactions
Vetsulin VetPen, 10 x 2.7 ml Cartridges ingredients
Vetsulin is a sterile aqueous zinc suspension of purified porcine insulin. Each mL contains:
  • 40 IU of purified porcine insulin (35% amorphous and 65% crystalline)
  • 7.0 mg of Sodium chloride
  • 1.36 mg of Sodium acetate trihydrate
  • 1.0 mg of Methylparaben (preservative)
  • 0.08 mg of Zinc (as chloride)
pH is adjusted with hydrochloric acid and/or sodium hydroxide.
Vetsulin VetPen, 10 x 2.7 ml Cartridges overdose: What to do?
Contact your closest emergency pet hospital
What to know before using Vetsulin VetPen, 10 x 2.7 ml Cartridges
  • Effectiveness and safety have not been evaluated in kittens or puppies, or in lactating, pregnant, or breeding cats or dogs.
  • Product exposure could cause a systemic or local allergic reaction for sensitized individuals.
  • Seek immediate medical attention upon accidental injection. This can cause clinical hypoglycemia.
  • Avoid contact with the eyes. If contact occurs, immediately begin flushing eyes for 15 minutes with copious amounts of water.
  • Vetsulin is not recommended during hypoglycemic periods.
  • Pets known to have systemic pork or pork product allergies should not be prescribed Vetsulin.
  • Keep out of reach of animals and children.
How is Vetsulin VetPen, 10 x 2.7 ml Cartridges sold?
Sold as 10 x 2.7 ml (40 units per ml) cartridges for use exclusively with VetPens (#50992) and VetPen Needles 12 mm (29 g) (#50990) sold separately.
Manufacturer
Merck
Overview
Use as directed by your veterinarian

Vetsulin VetPen Cartridges should be used exclusively with VetPens (#50992) and VetPen Needles 12 mm (29 g) (#50990) sold separately. 

Prior to loading Vetsulin cartridges, shake the cartridge until a homogeneous, uniformly milky suspension is obtained. Clumps or white particles can form in insulin suspensions: do not use the product if visible clumps or white particles persist after shaking.

The detailed instructions for use provided with VetPen should be strictly followed.

The injection should be administered subcutaneously, 2 to 5 cm (3/4 to 2 in) from the dorsal midline, varying from behind the scapulae to the mid-lumbar region and alternating sides.


Dogs

The initial recommended vetsulin® dose is 0.5 IU insulin/kg body weight. Initially, this dose should be given once daily concurrently with, or right after a meal.

Twice daily therapy should be initiated if the duration of insulin action is determined to be inadequate. If twice daily treatment is initiated, the two doses should each be 25% less than the once daily dose required to attain an acceptable nadir. For example, if a dog receiving 20 units of vetsulin® once daily has an acceptable nadir but inadequate duration of activity, the vetsulin® dose should be changed to 15 units twice daily.

The veterinarian should re-evaluate the dog at appropriate intervals and adjust the dose based on clinical signs, urinalysis results, and glucose curve values until adequate glycemic control has been attained. Further adjustments in dosage may be necessary with changes in the dog’s diet, body weight, or concomitant medication, or if the dog develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder.


Cats

The initial recommended dose in cats is 1 to 2 IU per injection. The injections should be given twice daily at approximately 12 hour intervals. For cats fed twice daily, the injections should be given concurrently with, or right after each meal. For cats fed ad libitum, no change in feeding schedule is needed.

The veterinarian should re-evaluate the cat at appropriate intervals and adjust the dose based on clinical signs, urinalysis results, and glucose curve values until adequate glycemic control has been attained. Further adjustments in dosage may be necessary with changes in the cat’s diet, body weight, or concomitant medication, or if the cat develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder.
Main Ingredients
Vetsulin VetPen Cartridge 2.7 ml (40 units per ml) is for use with VetPens (#50992) and VetPen Needles 12 mm (29 g) (#50990) sold separately.

Vetsulin is a sterile aqueous zinc suspension of purified porcine insulin.

Each mL contains:
purified porcine insulin (35% amorphous and 65% crystalline) 40 IU
Zinc (as chloride)  0.08 mg
Sodium acetate trihydrate 1.36 mg
Sodium chloride 7.0 mg
Methylparaben (preservative) 1.0 mg

pH is adjusted with hydrochloric acid and/or sodium hydroxide.