Iverhart Plus vs Trifexis

Keep your precious pup safe and healthy when you choose the right parasite and heartworm preventative for his or her specific needs. A couple of the best-loved options are Iverhart Plus and Trifexis. These two products are effective, safe, and well-known, but they differ in many ways. Keep reading to see how these two medications compare!

How do Iverhart Plus and Trifexis differ?

These two medications have many features in common. Perhaps the most notable similarity is that both of these prescription products protect dogs against heartworms, roundworms, and hookworms. Both formulas are made to be administered monthly, and they both come in the form of a tasty, chewable tablet. Iverhart Plus offers a pork flavor, and Trifexis is beef-flavored. Finally, both products are safe for use in puppies. Iverhart Plus can be used in puppies as young as 6 weeks of age, while Trifexis can be given to puppies over 8 weeks old weighing a minimum of 5 pounds.

These formulas are also unique from one another in many ways. Iverhart Plus contains Ivermectin and Pyrantel Pamoate, and it is safe for use in pregnant or breeding dogs.

Trifexis offers an entirely different duo of active ingredients - Milbemycin Oxime and Spinosad. In addition to the parasites listed above, Trifexis offers added protection against whipworms. It also works to kill fleas, going to work to eliminate all biting fleas within just 4 hours. This formula has not been proven safe for use in pregnant, breeding, or lactating dogs.

How can I make the choice between Iverhart Plus and Trifexis?

Choosing between these two products can be challenging. After all, you truly can’t go wrong when you elect to keep your dog healthy with either of these incredible medications. However, there are a couple of ways to make this important decision.

Firstly, will you be treating a pregnant or breeding dog? If so, Iverhart Plus is the safest choice. Secondly, are you concerned with protecting your dog against fleas and whipworms? If your dog is already taking a flea and tick preventative, he or she may not need the broad-spectrum protection provided by Trifexis. If your pup isn’t on any such medication, Trifexis could be the best choice for your beloved canine companion.

Talk to your veterinarian to determine which of these products is right for your dog. With your pup’s prescription in hand, come to Allivet for the lowest prices and the best selection of top-quality medications, supplements, treats, food, and so much more. You can also take advantage of our free pet parent consultations! Our licensed pharmacists are standing by to address all of your questions and concerns about each and every Allivet product.

Feature Iverhart Plus Trifexis
Kills Fleas No Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No Yes
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Hookworms and Toundworms Roundworms, Hookworms, and Whipworms
Waterproof Yes since taken orally Yes
How Long to work N/A Kills 100% of biting fleas in 4 hours
Taste Pork flavored Beef flavored
Active Ingredient Ivermectin and Pyrantel Pamoate Spinosad and Milbemycin Oxime
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age Dogs 6 weeks and older Puppies 8 weeks and older and weigh more than 5 lbs.
Manufacturer Virbac Elanco Animal Health
Safety Safe for pregnant or breeding females. Not yet evaluated for use of in breeding, pregnant, or lactating dogs.