Trifexis vs Sentinel
Your dog brings joy and happiness to your life. Keep your precious pup going strong with a great parasite treatment!. Allivet has created a comparison chart between Trifexis Chewable Tablets and Sentinel to help you find the product that best suits your dog;s needs. With the additional information below, you should be able to make a confident, informed decision.
What are the differences between Trifexis and Sentinel
One difference between these products is that Trifexis kills existing flea infestations, while Sentinel eliminates fleas in the larvae and egg stages. Both products are chewable tablets, and they each prevent parasitic infections. Sentinel can be given to puppies as early as 4 weeks of age, while Trifexis requires the puppy to be at least 8 weeks of age and weigh more than 5 pounds.
Trifexis contains Spinosad and Milbemycin Oxime and begins to kill fleas in as little as 30 minutes. It eliminates all fleas within 4 hours. Sentinel uses Milbemycin Oxime and Lufenuron to eradicate worm infestations and control fleas. Unlike Sentinel, Trifexis has not yet been evaluated for use in breeding, pregnant, or lactating dogs. Sentinel is safe for use in these dogs.
Both medications prevent heartworms and control roundworms, hookworms, and whipworms. Trifexis and Sentinel require a prescription from your veterinarian. Your vet should be able to answer any questions related to side effects, precautions, or special care for your dog.
Final Thoughts on Trifexis vs Sentinel
There is a noticeable difference in cost difference between Trifexis and Sentinel. While Sentinel may be more affordable, some pet owners may prefer Trifexis. Certain dog parents may switch over to Sentinel to protect breeding, pregnant, and lactating dogs. Due to the age at which you can give Sentinel, some pet owners may start their puppy on Sentinel, then shift to Trifexis as the dog ages.
If you still have questions on which oral flea and tick treatment is best for your furry friend, our pharmacists are standing by to offer pet parent consulting.
| Feature | Trifexis | Sentinel |
|---|---|---|
| Kills Fleas | Yes | No |
| Repels Fleas | No | No |
| Kills Flea Eggs and Larvae | Yes | Yes |
| Kills Ticks | No | No |
| Repels Ticks | No | No |
| Repels Mosquitoes | No | No |
| Prevents Heartworm | Yes | Yes |
| Other Parasites | Roundworm, hookworm, and whipworm | Roundworms, Whipworms, and Hookworms |
| Waterproof | Yes since taken orally | Yes since taken orally |
| How Long to work | Kills 100% of biting fleas in 4 hours | Breaks cycle of fleas and eggs. Does not kill existing flea infestation. |
| Taste | Beef Flavored | Savory Beef |
| Active Ingredient | Spinosad and Milbemycin Oxime | Milbemycin Oxime and Lufenuron |
| RX Required | Yes | Yes |
| Application Type | Chewable Tablet | Chewable Tablet |
| Dosing | 1 tablet per month | 1 tablet per month |
| Age | Puppies 8 weeks and older and weigh more than 5 lbs. | Dogs 4 weeks and older |
| Manufacturer | Elanco Animal Health | Virbac |
| Safety | Not yet evaluated for use of in breeding, pregnant, or lactating dogs. | Breeding, pregnant, and lactating dogs may use. |
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