Iverhart Plus vs Simparica Trio

Choosing medications to protect your dog against parasites and heartworms is an important step toward keeping your pup protected against dangerous and irritating pests. Iverhart Plus and Simparica Trio are two of the top options on the market today. Each product boasts a unique set of advantages and features, which we have outlined below in an effort to help you make the right choice for your canine companion.

Iverhart Plus for Dogs

Buy Iverhart Plus Today

Save $5 off $50
with coupon code COMPARE5
Simparica Trio

Buy Simparica Trio Today

Save $5 off $50
with coupon code COMPARE5

What are the key differences between Iverhart Plus and Simparica Trio?

These two medications share a few key similarities. Chief among these parallels is that both products protect dogs against roundworms, hookworms, and heartworms. Both formulas come in a chewable, once-monthly, prescription-only tablet (with Iverhart Plus offering a pork flavor and Simparica featuring a beef flavor). Finally, both products are safe for use in puppies. Iverhart Plus can be administered from 6 weeks and up, while Simparica Trio is safe for puppies over 2.8 pounds and 8 weeks of age.

These formulas differ in several ways as well. Perhaps the most notable difference between these medications is that they contain different active ingredients. Iverhart Plus contains Pyrantel Pamoate and Ivermectin, and Simparica Trio offers a trio of ingredients - Pyrantel, Moxidectin, and Saroloner.

In addition to the parasites listed above, Simparica Trio offers added protections. It works to kill fleas in the larval, egg, and adult stages. It also eliminates ticks. This formula has not been evaluated for safe use in lactating, breeding, or pregnant dogs.

Choosing between Iverhart Plus and Simparica Trio

When deciding between these two products, your choice might come down to your puppy’s age or weight. If you have a puppy that weighs less than 2.8 pounds or is between 6 and 8 weeks old, Iverhart Plus is the safest option. If your puppy is over 2.8 pounds and 8 weeks old, you can safely choose either of these effective formulas.

Your decision might hinge on whether or not your dog is already taking a flea and tick preventative. Flea and tick prevention is important for every dog. Therefore, if your pup isn’t already protected against these bothersome and potentially dangerous parasites, you might want to choose a broad-spectrum option like Simparica Trio. If your dog is already taking a flea and tick preventative, ask your vet if Iverhart Plus is a good choice for your furry family member.

After a trip to the veterinarian’s office, you’ll want to come to Allivet with your dog’s prescription. We have all of the best medications, supplements, and other pet products you need to keep your dog happy and healthy. If you have any concerns or questions that you may have forgotten to ask your vet, reach out to the Allivet pharmacists for a free pet parent consultation!

Feature Iverhart Plus Simparica Trio
Kills Fleas No Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No Yes
Kills Ticks No Yes
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Hookworms and Roundworms Hookworms and Roundworms
Waterproof Yes since taken orally Yes
How Long to work N/A N/A
Taste Pork Flavored Beef Flavored
Active Ingredient Ivermectin and Pyrantel Pamoate Sarolaner, Moxidectin, and Pyrantel
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age Dogs 6 weeks and older Dogs 8 weeks and 2.8lbs or morer
Manufacturer Virbac Boehringer Ingelheim
Safety Safe for pregnant or breeding females. Has not been evaluated in breeding, pregnant, or lactating dogs.

Other Iverhart Plus Comparisons

Other Simparica Trio Comparisons