K9 Advantix II vs Credelio

Informed decisions are an important part of life, and pet parenthood is no exception to that rule! Picking the right flea and tick treatment for your dog plays a big part in keeping them happy and healthy. Two of the top options are K9 Advantix II and Credelio. Both products have their own unique set of advantages and features. Below, we’ve outlined some of the differences and similarities between these two treatments to help you make the right choice for your dog.

What makes K9 Advantix II and Credelio different from one another?

One notable difference between these two products is that Credelio is an oral flea and tick treatment, while K9 Advantix II is a topical formula. Both products are made for dogs and puppies. K9 Advantix is safe from an age of 7 weeks and up for dogs and puppies weighing a minimum of 4 pounds. Credelio can be used in puppies as young as 8 weeks of age weighing at least 4.4 pounds.

Credelio is a prescription-only product, and K9 Advantix II is available over-the-counter. Neither product should be used in a pregnant, breeding, or lactating dog without first consulting your veterinarian to determine safety. Each product is administered monthly.

Credelio contains the active ingredient Lotilaner, and K9 Advantix II combines Imidacloprid, Pyriproxyfen, and Permethrin. Credelio kills 100% of fleas within 12 hours and 98.7% of ticks within 8 hours. K9 Advantix II kills fleas within 12 hours. It also kills flea larvae and eggs, repels fleas and biting flies, kills and repels ticks and mosquitoes, and treats lice.

How can I choose between K9 Advantix II and Credelio?

To choose one of these top-quality products, just answer the following questions:

  • Do you have a puppy between the ages of 7 and 8 weeks? If so, K9 Advantix should be used in that time frame. After 8 weeks and 4.4 pounds, you’re free to choose either product.
  • Is flea and tick eradication your primary concern, or would your dog benefit from elimination of flea eggs and larvae and protection against fleas, ticks, biting flies, lice, and mosquitoes? If you would prefer the added protections, K9 Advantix II is an excellent option.
  • Do you prefer an over-the-counter or a prescription treatment? If you’d enjoy the convenience of an over-the-counter product, choose K9 Advantix II. If you’re more comfortable with a prescription from your veterinarian, opt for Credelio.

Once you’ve familiarized yourself with the pros and cons of each medication, it’s time to speak with your veterinarian. Your vet can prescribe treatment or make a recommendation for an over-the-counter medication. They can also answer your questions and address any concerns you might be facing. If you have any other questions about these or any other medication, contact the Allivet pharmacists for a pet parent consultation.

K9 Advantix II for Dogs

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Save $5 off $50
with coupon code COMPARE5
Save $5 off $50
with coupon code COMPARE5
Feature K9 Advantix II Credelio
Kills Fleas Yes Yes
Repels Fleas Yes No
Kills Flea Eggs and Larvae Yes No
Kills Ticks Yes Yes
Repels Ticks Yes No
Repels Mosquitoes Yes No
Prevents Heartworm No No
Other Parasites Lice & Biting Flies No
Waterproof Yes Yes since taken orally
How Long to work 12 hours to kill fleas Kills 100% of fleas in 12 hours and 98.7% of ticks in 8 hours.
Taste N/A Beef Flavored
Active Ingredient Permethrin, Imidacloprid, and Pyriproxyfen Lotilaner
RX Required No Yes
Application Type Topical Chewable Tablet
Dosing Monthly application 1 tablet per month
Age Puppies 7 weeks and older and weighing more than 4 lbs. Dogs 8 weeks and older that weigh at least 4.4 pounds
Manufacturer Bayer Animal Health Elanco
Safety Don't apply to cats Has not been evaluated for use in breeding, pregnant, and lactating dogs.