Simparica vs Credelio

If you’re a pet parent, chances are, you’ll find yourself searching for the best flea and tick treatment to protect your pet against potentially harmful parasites. Two of the most frequently-prescribed treatment options are Simparica Tablets and Credelio Tablets. Both of these medications are excellent ways to keep your pet healthy, but there are some distinct differences that can help you weigh these options against each other. We’ve put together a table and some additional information to help you make an informed decision.

Simparica

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Credelio for Dogs and Puppies

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What are the key differences between Simparica and Credelio?

First of all, let’s discuss the similarities between these two medications. You’ve probably already noticed that both of these treatments are once-monthly, chewable tablets. They are both effective in killing fleas and ticks, and neither option is considered safe for use in lactating, pregnant, or breeding dogs. Finally, both of these oral flea and tick treatments are available only with a prescription from a veterinarian.

There are some differences between these two options that should be considered before you make your decision. Firstly, these medications have different active ingredients - Simparica contains Saroloner to kill fleas within 3 hours and ticks within 8, and Credelio uses Lotilaner to kill fleas in 12 hours and ticks in 8. While similar, these ingredients are not identical. Secondly, Credelio is formulated for use in puppies a minimum of 4.4 pounds and 8 weeks old, while Simparica is safe for puppies 2.8 pounds and 6 months old. Finally, Credelio is slightly more expensive than Simparica.

How do I make the decision between Simparica and Credelio?

The first factor you might want to consider is the age of your dog. If your dog is under the age of 6 months, but older than 8 weeks, Credelio is a great option. If your dog is over 6 months old, you might opt for Simparica instead. You’ll also want to speak with your veterinarian about your dog’s health history and lifestyle, and about your own concerns and preferences. Your vet can help you make the best decision for your dog.

Once you’ve obtained a prescription, come to Allivet for the best prices on top-quality prescriptions. If you have further questions, the Allivet pharmacists are here to help pets and their parents!

Feature Simparica Credelio
Kills Fleas Yes Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No No
Kills Ticks Yes Yes
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm No No
Other Parasites No No
Waterproof Yes since taken orally Yes since taken orally
How Long to work Kills fleas within 3 hours and ticks within 8 hours. Kills 100% of fleas in 12 hours and 98.7% of ticks in 8 hours.
Taste Liver Beef Flavored
Active Ingredient Sarolaner Lotilaner
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age Dogs 6 months and older weighing at least 2.8 pounds Dogs 8 weeks and older that weigh at least 4.4 pounds
Manufacturer Zoetis Elanco
Safety Not approved for breeding, pregnant, and lactating dogs. Has not been evaluated for use in breeding, pregnant, and lactating dogs.

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