Comfortis vs Advantage II

Keep yourself and your pet healthy by choosing a parasite treatment are Comfortis Chewable Tablets and Advantage II.While you can’t go wrong with either of these effective treatment options, there are some differences that might help you decide between the two. The table and information below are designed to help you make the best choice for your pet!

Comfortis Chewables for Dogs

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Advantage II

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How do Comfortis and Advantage II compare?

There are many differences between these two treatments, and understanding these differences can help you decide which choice is best for your pet. Comfortis is a chewable, once-monthly product that works to kill fleas. It starts working within 30 minutes. Advantage II is a topical, once-monthly treatment that kills fleas, flea larvae, and flea eggs, and it also treats lice. It starts killing fleas within 12 hours.

Comfortis is a prescription-only product, while Advantage II is available over-the-counter. You should consult your veterinarian before using either of these products on a lactating, pregnant, or nursing dog.

Comfortis contains the active ingredient Spinosad, and Advantage II contains Pyriproxyfen and Imidacloprid. Comfortis is safe for use in cats and dogs ages 14 weeks and up, and Advantage II is safe for puppies 7 weeks or older.

How do I choose between Comfortis and Advantage II?

First, consider whether you’re planning to treat a puppy between the ages of 7 weeks and 14 weeks. (If you’re looking for parasite treatment are Advantage II for Cats, there is a formula for kittens and cats ages 8 weeks and up.) If so, Advantage II is a great choice. If your puppy is over the age of 14 weeks, you can choose either of these incredible treatments. If you prefer topical application, you’ll want to use Advantage II. If you prefer oral medications, Comfortis is a great choice. Finally, if you’re simply looking for an effective flea control product, Comfortis is an ideal choice. If your dog needs broad-spectrum parasite protection and control, Advantage II might be the best product

Speak to your veterinarian about these two products. Your vet can help you make the best decision for your pet’s needs. If you have any lingering questions or concerns about oral flea and tick treatment or any other medications your pet might be taking, the Allivet pharmacists are ready and waiting to consult with pet parents!

Feature Comfortis Advantage II
Kills Fleas Yes Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No Yes
Kills Ticks No No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm No No
Other Parasites No Treats lice
Waterproof Yes since taken orally Yes
How Long to work Begins to kills fleas in 30 minutes Begins to kill fleas within 12 hours
Taste Beef flavored N/A
Active Ingredient Spinosad Imidacloprid and Pyriproxyfen
RX Required Yes No
Application Type Chewable Tablet Topical
Dosing 1 tablet per month 1 application per month
Age Dogs and cats 14 weeks and older Dogs 7 weeks and older
Manufacturer Elanco Animal Health Bayer Animal Health
Safety Not evaluated for safe use in breeding, pregnant, and lactating dogs. Speak to your vet about risks associated with breeding, pregnant, or lactating dogs

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