Advantage Multi vs Frontline Plus

If there’s one thing pet parents can agree on, it’s the fact that it’s important to keep your dog healthy and happy. That’s why choosing the right flea treatment is essential. Two of the best products available are Advantage Multi and Frontline Plus It might be tough to weigh these options, but we’ve assembled a table and some additional information to help you make a great decision for your pup.

Advantage Multi for Dogs

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Frontline Plus for Dogs

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How does Advantage Multi differ from Frontline Plus?

To start, we’ll detail the parallels between these two products. First of all, they are both once-monthly topical treatments. They are both safe for use in puppies (Advantage Multi can be used on puppies as young as 7 weeks old weighing a minimum of 3 pounds, and Frontline Plus is safe for puppies 8 weeks and up). Both products kill fleas, getting to work within 12 hours to eliminate infestations.

There are more differences than similarities, which might help make your decision a little easier. For starters, they each contain different active ingredients. Frontline Plus combines (S)-Methoprene and Fipronil, while Advantage Multi uses Imidacloprid and Moxidectin. Frontline Plus is proven safe for use in pregnant, lactating, or breeding dogs, while Advantage Multi should only be used in these dogs if your veterinarian has determined safety.

Advantage Multi is available only with a prescription, while Frontline Plus is an over-the-counter option. Frontline Plus offers added protection against ticks, working to kill the potentially dangerous parasites within 48 hours. It also kills flea larvae and eggs and treats lice. Advantage Multi prevents heartworm disease, along with hookworms, roundworms, and ear mites.

Closing thoughts on Advantage Multi vs. Frontline Plus

To make a decision between these two top-quality treatments, you’ll want to consider the additional parasites you’d like to protect against. If your dog isn’t already taking a heartworm preventative, your veterinarian will likely recommend Advantage Multi. If your dog requires hookworm, roundworm, and/or ear mite protection, Advantage Multi is a great choice for those purposes, too. Frontline Plus is an ideal option for lice treatment, or for dogs requiring full-spectrum protection against fleas and ticks.

After considering these differences, you’ve probably decided which product might be best for your dog. Armed with that knowledge, you’ll want to contact your veterinarian for a prescription if you’ve chosen Advantage Multi for your dog. Your vet will also be happy to answer any questions you might have. The Allivet pharmacists are also standing by to address any additional concerns or answer any other questions you might have!

Feature Advantage Multi Frontline Plus
Kills Fleas Yes Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No Yes
Kills Ticks No Yes
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes No
Other Parasites Ear mites, roundworms, and hookworms Treats lice
Waterproof Yes Yes
How Long to work Begins to kill fleas within 12 hours 12 hours to kill fleas and 48 hours to kill ticks
Taste N/A N/A
Active Ingredient Imidacloprid and Moxidectin Fipronil and (S)-Methoprene
RX Required Yes No
Application Type Topical Topical
Dosing 1 application per month 1 topical application per month
Age Dogs 7 weeks and older that weight at least 3 pounds Dogs 8 weeks and older
Manufacturer Bayer Animal Health Boehringer Ingelheim
Safety Speak to your vet about risks associated with breeding, pregnant, or lactating dogs Breeding, pregnant, and lactating dogs may use.

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