Simparica vs K9 Advantix II

An important part of keeping your dog healthy is keeping fleas and ticks at bay. Two great ways to protect your dog against potentially harmful fleas and ticks are Simparica Tablets and K9 Advantix II. Each product is unique and has its own way of treating infestations. See below for a table and additional information about these two effective flea and tick treatments!

Simparica

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K9 Advantix II Flea Treatment

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What are the differences between Simparica and K9 Advantix II?

Firstly, Simparica is an oral flea and tick treatment, while K9 Advantix II is a topical treatment. They are both administered monthly. Simparica is available only with a prescription from a veterinarian, while K9 Advantix II is available without a prescription.

Simparica uses Saroloner to kill fleas and ticks. K9 Advantix II contains Pyriproxyfen, Imidacloprid, and Permethrin, which work together to kill ticks and fleas. These ingredients also repel mosquitoes, fleas, and ticks, and they kill flea larvae and eggs. Simparica kills fleas within 3 hours and kills ticks within 8 hours. K9 Advantix II kills fleas within 12 hours.

Simparica is safe for use in dogs over 2.8 pounds and 6 months old. K9 Advantix II can be used on puppies over 4 pounds and 7 weeks old. Neither medication should be used in cats. If your pet is pregnant, lactating, or breeding, you should consult your veterinarian for treatment options.

Key takeaways on Simparica vs. K9 Advantix II

The age of your dog may help you determine which of these treatment options is best. You might choose K9 Advantix II because you prefer topical application or because it is available over the counter, or you may opt for Simparica because of its mess-free, oral administration. If you prefer a product that repels parasites, or if cost is your primary concern, K9 Advantix II might be your best bet. If you wish to give your dog a prescription-only treatment, Simparica is a great way to protect your dog.

Your veterinarian is a great resource for helping you choose the flea and tick treatment option that works best for your individual dog’s needs. Your vet will also be able to answer your questions about these and any other medications. If you have additional concerns or questions, you can also consult the pharmacists at Allivet!

Feature Simparica K9 Advantix II
Kills Fleas Yes Yes
Repels Fleas No Yes
Kills Flea Eggs and Larvae No Yes
Kills Ticks Yes Yes
Repels Ticks No Yes
Repels Mosquitoes No Yes
Prevents Heartworm No No
Other Parasites No No
Waterproof Yes since taken orally Yes
How Long to work Kills fleas within 3 hours and ticks within 8 hours. 12 hours to kill fleas
Taste Liver N/A
Active Ingredient Sarolaner Permethrin, Imidacloprid, and Pyriproxyfen
RX Required Yes No
Application Type Chewable Tablet Topical
Dosing 1 tablet per month Monthly application
Age Dogs 6 months and older weighing at least 2.8 pounds Puppies 7 weeks and older and weighing more than 4 lbs.
Manufacturer Zoetis Bayer Animal Health
Safety Not approved for breeding, pregnant, and lactating dogs. Don't apply to cats

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