Interceptor vs Simparica Trio

As a pet parent, your primary concern is the health of your pet. Choosing a parasite preventative is an important way to keep your pet happy, healthy, and protected. Interceptor and Simparica Trio are two of the most popular options on the market today. Both of these treatments can go a long way toward keeping your pet healthy, but they differ in a variety of ways, too. Keep reading to learn how they compare!

Interceptor for Dogs

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Simparica Trio for Dogs and Puppies

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How do Interceptor and Simparica Trio differ?

These two top-of-the-line medications are similar in many ways. They are both chewable, once-monthly, prescription-only, beef-flavored tablets. They both protect against heartworm disease, and they both protect against hookworms and roundworms. Both products are safe for use in puppies - Interceptor can be administered to puppies at least 4 weeks old weighing a minimum of 2 pounds, and Simparica Trio is safe for puppies at least 8 weeks old weighing a minimum of 2.8 pounds.

Each of these products offer a number of unique advantages to set them apart from one another.

Interceptor contains the active ingredient Milbemycin Oxime. This ingredient is safe for use in cats, as well as lactating, breeding, and pregnant pets. It offers added protection against whipworms.

Simparica Trio combines three active ingredients - Saroloner, Moxidectin, and Pyrantel. These ingredients team up to provide added protection against flea larvae, flea eggs, fleas, and ticks. This product has not been proven safe for use in pregnant, lactating, or breeding pets, and it should not be administered to cats.

How do I choose between Interceptor and Simparica Trio?

To choose between these two products, you’ll want to consider a few different factors.

  • Do you intend to treat a puppy between 4 and 8 weeks old, a cat, or a breeding, pregnant, or lactating pet? If so, Interceptor is the safest choice.
  • Do you wish to protect your pet against whipworms, or would your pet benefit more from flea and tick protection? If whipworms are most concerning to you, or if your pet is already taking a flea and tick preventative, Interceptor might be the best option. (Be sure to speak to your veterinarian before combining medications.) If your dog is not currently taking a flea and tick preventative, Simparica Trio is a great, broad-spectrum choice.

Once you’ve narrowed your search, it’s time to schedule an appointment with your veterinarian. Be sure to ask your vet whether or not the option you’ve chosen is best for your pet, and come to the appointment armed with your questions and concerns. If you think of a question after your appointment, that’s what the Allivet pharmacists are here for! They are standing by to offer free pet parent consultations, and they are knowledgeable on every Allivet product.

Feature Interceptor Simparica Trio
Kills Fleas No Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No Yes
Kills Ticks No Yes
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Hookworms, Whipworms, Roundworms Hookworms and Roundworms
Waterproof Yes since taken orally Yes
How Long to work N/A N/A
Taste Beef Flavored Beef Flavored
Active Ingredient Milbemycin Oxime Sarolaner, Moxidectin, and Pyrantel
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age 4 weeks or older and weighing 2 lbs. or greater Dogs 8 weeks and 2.8lbs or more
Manufacturer Elanco Boehringer Ingelheim
Safety Breeding, pregnant, and lactating dogs may use. Has not been evaluated in breeding, pregnant, or lactating dogs.

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