Advantage II vs Sentinel
Pet parents are always trying to find the best products to keep their dog protected against irritating and potentially dangerous pests. Two of the top products for parasite treatment include Advantage II and Sentinel. While these products share some similarities, there are also some significant differences that may help you choose between the two. To help with your decision, we’ve assembled a table and some more information below.
What makes Advantage II different from Sentinel?
There are many differences that make each of these products appealing in their own ways. Sentinel is a heartworm preventative. that uses Lufenuron and Milbemycin Oxime to control hookworms, roundworms, and whipworms. It also breaks the flea life cycle by inhibiting the development of larvae and eggs, but it is not effective against existing infestations of adult fleas. Advantage II is a topical flea treatmentthat combines Pyriproxyfen and Imidacloprid for added protection against heartworms, lice, and flea larvae and eggs.
Sentinel is safe for use in pregnant, lactating, or breeding dogs, while Advantage II should only be administered to these dogs with approval from a veterinarian. Sentinel is safe for puppies as young as 4 weeks of age, and Advantage II can be used from an age of 7 weeks and up. Sentinel is made only for dogs, while Advantage II offers a separate product to protect your cat.
Sentinel is available only with a prescription, and Advantage II is an over-the-counter option.
Closing thoughts about Advantage II vs. Sentinel
The first consideration you’ll want to weigh is the age of your dog. If you have a puppy between the ages of 4 and 7 weeks, Sentinel is a great way to begin protection early. You might opt to continue administering Sentinel after the 7-week mark, or you may choose to switch to Advantage II. If your dog is prone to lice, Advantage II might be a great way to keep that problem at bay. If you are more concerned about intestinal parasites, you might choose to use Sentinel.
Talk to your veterinarian about the decision you’ve made. Your vet can confirm that the product you select is the best one to protect your specific dog. If you think of any questions or concerns and you could benefit from a pet parent consultation, just reach out to the Allivet pharmacists!
| Feature | Advantage II | Sentinel |
|---|---|---|
| Kills Fleas | Yes | No |
| Repels Fleas | No | No |
| Kills Flea Eggs and Larvae | Yes | Stops development |
| Kills Ticks | No | No |
| Repels Ticks | No | No |
| Repels Mosquitoes | No | No |
| Prevents Heartworm | Yes | Yes |
| Other Parasites | Treats lice | Roundworms, Whipworms, and Hookworms |
| Waterproof | Yes | Yes since taken orally |
| How Long to work | Begins to kill fleas within 12 hours | Breaks cycle of fleas and eggs. Does not kill existing flea infestation. |
| Taste | N/A | Savory Beef |
| Active Ingredient | Imidacloprid and Pyriproxyfen | Milbemycin Oxime and Lufenuron |
| RX Required | No | Yes |
| Application Type | Topical | Chewable Tablet |
| Dosing | 1 application per month | 1 tablet per month |
| Age | Dogs 7 weeks and older | Dogs 4 weeks and older |
| Manufacturer | Bayer Animal Health | Virbac |
| Safety | Speak to your vet about risks associated with breeding, pregnant, or lactating dogs | Breeding, pregnant, and lactating dogs may use. |
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