Interceptor Plus vs Simparica Trio

As a loving pet parent, you’re always trying to find ways to protect your dog and make his or her life better. That’s why parasite and heartworm prevention are such important tasks. With the many options available, choosing the best one for your dog can be a tall order. Interceptor Plus and Simparica Trio are two of the best products on the market. They both provide safe and dependable parasite protection, but they are also different in a number of ways. Keep reading to learn more!

Interceptor Plus for Dogs

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Simparica Trio

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How does Interceptor Plus differ from Simparica Trio?

First, let’s talk about the many similarities between these two medications. Perhaps most importantly, both of these formulas protect dogs against heartworms, roundworms, and hookworms. They are both chewable, once-monthly, prescription-only tablets. Interceptor Plus boasts a savory chicken flavor, while Simparica Trio offers a tasty beef flavor. Both products are also safe for use in puppies. Interceptor Plus can be safely administered to puppies ages 6 weeks and up weighing at least 2 pounds, and Simparica Trio is safe for puppies ages 8 weeks and up weighing at least 2.8 pounds.

Now, let’s weigh the differences between Interceptor Plus and Simparica Trio. Interceptor Plus contains two active ingredients - Praziquantel and Milbemycin Oxime. In addition to the parasites mentioned above, this formula also protects against whipworm and tapeworm infections. It is safe for use in pregnant, lactating, or breeding dogs. While neither treatment is formulated for use in cats, Interceptor does offer a separate product (Interceptor for Dogs and Cats) that is cat-safe.

Simparica Trio contains three active ingredients - Pyrantel, Moxidectin, and Saroloner. This medication doubles as a flea and tick preventative, and it is effective against fleas in the larvae, egg, and adult stages. This product has not been proven safe for use in pregnant, lactating, or breeding dogs.

Final thoughts on Interceptor Plus vs. Simparica Trio

Both of these products are well-liked because they are incredibly safe and effective. However, you can only administer one of them - so which one will it be?! Either way, your dog will be protected against heartworms, roundworms, and hookworms. Your decision will likely depend on the additional parasites you want to protect against. If your dog is already taking a flea and tick preventative, and if he or she could benefit from whipworm and tapeworm protection, you’ll want to opt for Interceptor Plus. If your dog is not already on a flea and tick preventative and you would prefer a broad-spectrum medication, Simparica Trio is a great choice.

Talk to your veterinarian about these treatment options. He or she can help you make the best decision for your dog. Be sure to bring your prescription to Allivet for low prices on the best medications you’ll find anywhere! Our licensed pharmacists are also available for pet parent consultations if you have any questions or concerns about any Allivet product.

Feature Interceptor Plus Simparica Trio
Kills Fleas No Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No Yes
Kills Ticks No Yes
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm Yes Yes
Other Parasites Hookworms, Roundworms, Tapeworms and Whipworms Hookworms and Roundworms
Waterproof Yes since taken orally Yes
How Long to work N/A N/A
Taste Chicken Flavor Beef Flavored
Active Ingredient Milbemycin Oxime and Praziquantel Sarolaner, Moxidectin, and Pyrantel
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age Dogs ages 6 weeks and 2lbs or more Dogs 8 weeks and 2.8lbs or more
Manufacturer Elanco Boehringer Ingelheim
Safety Breeding, pregnant, and lactating dogs may use. Has not been evaluated in breeding, pregnant, or lactating dogs.

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