K9 Advantix II vs Sentinel

Pet parents can agree on one thing - it’s essential that your dog stays happy and healthy. That’s why choosing a great parasite treatment is so important. Two of the top-recommended products are K9 Advantix II and Sentinel. It can be hard to weigh the options, but we’ve put together a table and more information to help you make a good decision to protect your dog.

What makes K9 Advantix II different from Sentinel?

There are a number of differences between these two incredible products. Sentinel is an oral heartworm preventative, and it offers added protection against hookworms, whipworms, and roundworms. It ends the flea life cycle by killing flea larvae and eggs, but it is not effective against existing infestations. K9 Advantix II is a topical flea and tick treatment. It kills and repels fleas, ticks, and mosquitoes, repels biting flies, kills flea eggs and larvae, and treats lice.

K9 Advantix II contains Pyriproxyfen, Permethrin, and Imidacloprid. It is safe for use in puppies and dogs weighing over 4 pounds and a minimum of 7 weeks old. Sentinel uses Lufenuron and Milbemycin Oxime, and it is safe from an age of 4 weeks. Each product is administered monthly.

K9 Advantix II is an over-the-counter treatment, while Sentinel requires a prescription. Both products are intended only for dogs and should not be used in cats. Sentinel is safe for use in lactating, pregnant, or breeding dogs, but K9 Advantix II is not.

Closing thoughts on K9 Advantix II vs. Sentinel

Now that we’ve weighed the many advantages of these two effective treatment options, it’s time to help you with your decision. Simply answer the following questions, and your choice will likely become quite clear!

  • Do you prefer a prescription product like Sentinel, or would an over-the-counter option like K9 Advantix II be best for you and your dog?
  • Is your dog already taking a heartworm and intestinal parasite preventative? If not, Sentinel is a great way to provide your dog with reliable protection against deadly disease. If so, K9 Advantix does not offer heartworm preventative benefits, but can protect your dog against a number of other dangerous parasites and diseases.
  • Does your dog spend lots of time outdoors? If the answer is yes, K9 Advantix is a great way to protect them against mosquitoes, fleas, ticks, biting flies, and lice which are prevalent in outdoor environments.
  • Is your dog pregnant, breeding, or lactating? If so, you may choose Sentinel.

Your veterinarian might even recommend that you administer both products to your dog simultaneously for broad-spectrum protection against harmful parasites. Of course, you should never administer any medication without first consulting your veterinarian.

If you find yourself with any questions about either of these products or any other product carried by Allivet, our pharmacists are here to help! Just reach out for a convenient pet parent consultation.

K9 Advantix II for Dogs

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Sentinel

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Feature K9 Advantix II Sentinel
Kills Fleas Yes No
Repels Fleas Yes No
Kills Flea Eggs and Larvae Yes Stops development
Kills Ticks Yes No
Repels Ticks Yes No
Repels Mosquitoes Yes No
Prevents Heartworm No Yes
Other Parasites Lice & Biting Flies Roundworms, Whipworms, and Hookworms
Waterproof Yes Yes since taken orally
How Long to work 12 hours to kill fleas Breaks cycle of fleas and eggs. Does not kill existing flea infestation.
Taste N/A Savory Beef
Active Ingredient Permethrin, Imidacloprid, and Pyriproxyfen Milbemycin Oxime and Lufenuron
RX Required No Yes
Application Type Topical Chewable Tablet
Dosing Monthly application 1 tablet per month
Age Puppies 7 weeks and older and weighing more than 4 lbs. Dogs 4 weeks and older
Manufacturer Bayer Animal Health Virbac
Safety Don't apply to cats Breeding, pregnant, and lactating dogs may use.

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