Simparica vs Sentinel

Informed decisions are important for most things in life. Choosing a flea and tick treatment for your dog is no exception. Two of the best options are Simparica Tablets and Sentinel Flavor Tabs. Each product offers its own advantages, making them both excellent options for keeping your dog healthy and protected. Keep reading to get the information you need to choose between these two incredible medications!

Simparica

Buy Simparica Today

Save $5 off $50
with coupon code COMPARE5
Sentinel

Buy Sentinel Today

Save $5 off $50
with coupon code COMPARE5

What are the differences between Simparica and Sentinel?

At a glance, it may appear that Simparica and Sentinel are pretty similar. They are both chewable tablets, they are both administered monthly, they each require a prescription from your veterinarian, and they are both great ways to keep your dog protected against dangerous parasites. There are many differences between these treatments, too. These differences might help you make the best decision to meet your dog’s specific needs.

The first notable difference is the coverage for each medication. Simparica uses Saroloner to kill fleas and ticks. Sentinel contains Milbemycin Oxime and Lufenuron, which work together to stop developing flea larvae and eggs, prevent heartworms, and control and remove adult whipworm and hookworm infestations. Based on your dog’s age, choosing between these medications might be easy - Sentinel is safe for use in puppies from an age of 4 weeks, while Simparica is approved for use in dogs over the age of 6 months.

Simparica is not proven safe for use in lactating, pregnant, or breeding dogs, while Sentinel may be administered to these dogs. Simparica kills existing fleas within 3 hours and kills existing ticks within 8 hours. Sentinel is intended as a preventative treatment, so it does not kill existing parasites. Sentinel works by breaking the flea life cycle.

How can I choose between Simparica and Sentinel?

The primary consideration that might help you decide between these two effective treatments is whether or not your dog has an existing infestation. If they do, Simparica might be the best choice. If your dog is frequently exposed to conditions that make infestation likely, Sentinel might be a better option.

If your dog is young (between the ages of 4 weeks and 6 months), lactating, pregnant, or breeding, Sentinel may be the way to go. If your dog is over the age of 6 months and is not breeding, lactating, or pregnant, Simparica is an excellent choice.

Be sure to ask your veterinarian which of these top-quality treatments is best for your dog. Your vet can answer any questions and address any concerns you might have about starting your dog on a new medication and keeping them protected. If you have any questions, the pharmacists at Allivet are available to consult with pet parents about these and any other medications your pet might be taking.

Feature Simparica NexGard
Kills Fleas Yes No
Repels Fleas No No
Kills Flea Eggs and Larvae No Stops development
Kills Ticks Yes No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm No Yes
Other Parasites No Roundworms, Whipworms, and Hookworms
Waterproof Yes since taken orally Yes since taken orally
How Long to work Kills fleas within 3 hours and ticks within 8 hours. Breaks cycle of fleas and eggs. Does not kill existing flea infestation.
Taste Liver Savory Beef
Active Ingredient Sarolaner Milbemycin Oxime and Lufenuron
RX Required Yes Yes
Application Type Chewable Tablet Chewable Tablet
Dosing 1 tablet per month 1 tablet per month
Age Dogs 6 months and older weighing at least 2.8 pounds Dogs 4 weeks and older
Manufacturer Zoetis Virbac
Safety Not approved for breeding, pregnant, and lactating dogs. Breeding, pregnant, and lactating dogs may use.

Other Simparica Comparisons

Other Sentinel Comparisons