Simparica vs Advantage II

Choosing a flea and tick treatment is essential in protecting your pet against irritating and potentially harmful pests. Two well-known options are Simparica Chewable Tablets and Advantage II for Dogs. Each medication features unique advantages, which are detailed below to help you choose the right treatment for your pet.

Simparica

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Advantage II for Dogs

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What makes Simparica different from Advantage II?

One distinct difference between these two treatments is the delivery method - Simparica is a tablet, while Advantage II is a topical product. Simparica contains Saroloner, while Advantage II combines Imidacloprid and Pyriproxyfen to protect your pet. Simparica can be administered to puppies beginning at an age of 6 months, and Advantage II is safe for puppies as young as 7 weeks.

Simparica is administered orally, and it provides your dog with a full month of protection. It begins working within 8 hours to kill ticks and fleas within 3. Advantage II starts working within 12 hours of application. Simparica is available only with a prescription from a veterinarian. However, Advantage II is available without a prescription, which may make it a more attractive option for some pet parents. Advantage II also offers added protection against lice.

Both Simparica and Advantage II are administered monthly, and the costs are comparable.

Final Thoughts on Simparica vs Nexgard

To choose between these two effective treatments, a few factors should be considered:

  • Do you prefer an oral flea and tick treatment (Simparica) or a topical one (Advantage II)?
  • What is the age of your dog? If you have a puppy under the age of 6 months (and over 7 weeks), you’ll want to opt for Advantage II. If your dog is over 6 months old, Simparica is a great option.
  • Are you searching for an over-the-counter option like Advantage II, or is a prescription like Simparica just as convenient for you?
For advice about which flea and tick treatment is best for your pet, consult your veterinarian and/or the pharmacists at Allivet!

Feature Simparica Advantage II
Kills Fleas Yes Yes
Repels Fleas No No
Kills Flea Eggs and Larvae No Yes
Kills Ticks Yes No
Repels Ticks No No
Repels Mosquitoes No No
Prevents Heartworm No Yes
Other Parasites No Treats lice
Waterproof Yes since taken orally Yes
How Long to work Kills fleas within 3 hours and ticks within 8 hours. Begins to kill fleas within 12 hours
Taste Liver N/A
Active Ingredient Sarolaner Imidacloprid and Pyriproxyfen
RX Required Yes No
Application Type Chewable Tablet Topical
Dosing 1 tablet per month 1 application per month
Age Dogs 6 months and older weighing at least 2.8 pounds Dogs 7 weeks and older
Manufacturer Zoetis Bayer Animal Health
Safety Not approved for breeding, pregnant, and lactating dogs. Speak to your vet about risks associated with breeding, pregnant, or lactating dogs

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